Canadian Company Announces Virtual Medical Consultations Anytime Anywhere
Sick? Click! (CNW Group/MyCare)
A Canadian telehealth company launches virtual medical consultations for episodic care that can be accessed from the privacy of home, office or hotel room.
MyCare MedTech Medical Clinic is utilizing advanced communication technology to connect a patient to a licensed medical provider through its innovative service, GOeVisit.
GOeVisit can diagnose, treat and prescribe for more than 30 non-emergency conditions, from common illnesses like cough, colds and flu, to general medical concerns, minor injuries and pediatric care. GOeVisit uses the same technology most people are already using daily, turning a computer, smartphone or tablet into a private, face-to-face medical consultation platform.
"GOeVisit is unique as it is the only service of its kind in Canada offering 24/7 and 365 access to medical practitioners from wherever a client lives, works or travels," said Dr. Raj Attariwala, Medical Director of AIM Medical Imaging in Vancouver and Medical Director of GOeVisit. "Virtual care is exploding, and GOeVisit is at the forefront, using proprietary Virtual Practice Guidelines to ensure clients receive an accurate consultation and treatment plan. The Virtual Practice Guidelines are well established and proven by multi-national corporations to help patients and parents quickly make appropriate health related decisions."
GOeVisit can provide prescriptions for non-controlled medications through its national prescription drug service. Using the Virtual Practice Guidelines (VPGs), GOeVisit providers may recommend over the counter medications or home therapies as alternatives to prescriptions. Use of VPGs has proven to reduce prescriptions by as much as 67%, an important alternative to the over prescription of medication, particularly antibiotics.
"Canadians are ready to take control of their healthcare," says Liz Bryant, Chief Operating Officer of MyCare MedTech Inc., "and want alternatives to waiting for non-emergency care. Two thirds of Canadians surveyed want to access care the way they access so many other services: through technology. GOeVisit makes that possible."
About MyCare MedTech Inc. MyCare MedTech Inc. is a Canadian telemedicine company with offices in Calgary, Alberta and Vancouver, BC. For more information, visit www.goevisit.com
National Survey reveals 91 per cent of Canadians believe health is the key to happiness
CHFA presents four simple ways to stay happy and healthy this winter
In response to new national survey results and with cold and flu season fast approaching, the Canadian Health Food Association (CHFA) have put together simple and effective tips to help Canadians stay happy and healthy during the winter months.
The survey of more than 1,500 Canadians conducted by CHFA revealed that the vast majority (91 per cent) of Canadians believe that their overall health impacts their level of happiness. The same survey also shows that more than half of our population (54 per cent) get sick most often in the winter.
When asked what factors are negatively impacting their health, Canadians from coast to coast reported that lack of sleep tops the list at 73 per cent. Sleep was followed closely by stress and lack of mindfulness (57 per cent), lack of exercise (52 per cent) and poor nutrition (46 per cent).
Additional interesting findings from the survey include:
Canadians’ favourite foods to ward off cold and fluand stay happy and healthy include chicken soup/broth (49 per cent), oranges (49 per cent) and tea (48 per cent).
Canadians’ top picks for natural health products to keep them happy and healthy during cold and flu seasoninclude vitamins C (46 per cent) and D (37 per cent).
Things Canadians do to stay happy and healthy:Over three-quarters say they improve their sleep (76 per cent), improve eating habits (43 per cent) and engage in exercise (40 per cent).
As Canadians prepare to celebrate the fifth annual National Health Products (NHP) Week, which runs from November 7 to 13, 2016, the focus is on practical and innovative ways to stay healthy through the holidays and into the New Year.
“Our goal this NHP Week is to arm Canadians with the tools they need to maintain health and happiness during cold and flu season,” said Michelle W. Book, CHFA’s in-house holistic nutritionist. “We identified four pillars of immunity, each including simple steps Canadians can take to help boost their immune system naturally this season and beyond.”
CHFA’s four pillars of immunity include:
Nutrition: Lack of proper nutrition has been linked to decreased immunity and increased risk of illness. Nuts, fermented foods and garlic are all shown to help boost the immune system.
Exercise: Engaging in 30-60 minutes every day can improve your body’s immune response. To improve exercise and immune health consider including krill oil, protein and vitamin D as part of your daily routine.
Sleep: Our bodies respond to lack of sleep in a similar way as it does to acute stress. Try adding magnesium, L-theanine and melatonin for better sleep.
Mindfulness: Mindfulness can reduce markers for inflammation and stress hormones. Probiotics and omega-3s can be beneficial in managing stress.
“While we always encourage Canadians to speak to their health care practitioners when they are under the weather, we also want to encourage everyone to consider adding natural health products to improve overall wellbeing and boost immunity,” says CHFA President Helen Long. “When you visit a local CHFA Member health food store, you can find all kinds of safe, effective and high-quality supplements, vitamins, minerals, herbal products and traditional medicines. Canadians should feel confident that Health Canada-approved natural health products can play an important role in maintaining and optimizing our health and happiness.”
Canadians should also be aware that Health Canada is proposing changes that impact natural health products in two fundamental ways:
Some products will no longer require Health Canada review and will provide less information.
Other products will be required to submit drug-level scientific evidence to support their claims.
About CHFA
The Canadian Health Food Association (CHFA) is Canada's largest national trade association dedicated to the natural health and organic products industry. The association represents manufacturers, retailers, wholesalers, distributors and importers of natural health and organic products. With a membership of more than 1,000 businesses across the country, CHFA represents an industry that contributes more than $6 billion to the Canadian economy. Michelle W. Book is CHFA’s in-house holistic nutritionist, trained in natural and complementary therapies.
About the survey:
A survey of 1591 Canadians was completed online between September 12th to 15th 2016 using Leger’s online panel, LegerWeb. A probability sample of the same size would yield a margin of error of +/-2.5per cent, 19 times out of 20.
VERY, VERY SURPRISING USES FOR BOTOX THAT HAVE NOTHING TO DO WITH FOREHEAD WRINKLES
When most people think of Botox the first thing that usually comes to mind is wrinkle reduction. Indeed, Botox is the world’s most popular treatment for eradicating wrinkles and fine lines. The toxin is specifically FDA approved for treating frown lines between the eyebrows (glabellar lines) and lines around the eyes (crow’s feet). In addition to being the gold standard for wrinkle reduction, Botox can also be used to treat a variety of issues, both cosmetic and non-cosmetic. Dr. John Zannis is a New Bern, North Carolina board certified plastic surgeon. He provides a list of conditions that Botox has been used to treat.
Acne
Botox can curb oil production, reducing breakouts. "To totally treat acne, you'd need to use doses of Botox so large they'd prevent you from constricting your facial muscles," says Dr. Zannis. "But tiny amounts of Botox injected very superficially help reduce oil production, and you can still have facial expressions." Though he'd recommend it for almost any patient struggling with acne, Zannis would likely advise trying another dermatologist-prescribed treatment, like spironolactone or birth control pills, first. And though it can technically be used to quell oil production anywhere on the face, he cautions against using it all over because of potential effects on muscular activity (a.k.a. frozen face). The most effective and common area for using Botox to curb oil production, he says, is the forehead.
Gummy smile (not FDA approved)
A "gummy" smile, one that's characterized by a smile that shows too much of the gums, usually results from "excessive lip elevation" when the upper lip rises too far above the upper teeth when smiling. Injecting Botox into the upper lip weakens the upper lip's retractor muscles so that it won't raise as high and your smile will seem better-balanced. It can be done in about five minutes. Usually lasts for four to six months. Costs range from $200-$300. Dr. Zannis says, "This technique is not for the novice Botox injector. Too much, and your lip won’t raise enough, too little and you will need more, or if injected asymmetrically, you might have a funny asymmetrical smile."
Urinary incontinence.
Overactive bladder problems affect up to 20% of women over 40. For severe cases where medications do not provide complete relief, Botox injections into the bladder wall may provide relief lasting about 6 months.
Psoriasis
Psoriasis is uncomfortable, itchy, and not exactly easy on the eyes. Luckily, this flaky skin condition could be a thing of the past thanks to Botox. Though psoriasis is technically incurable, Botox minimizes the activity of inflammatory cells that bring on outbreaks.
Excessive Sweating
For those who suffer from excessive sweating, however, summer isn’t always the sunniest time of the year. Thankfully, Botox could be a saving grace for those attempting to manage this condition, which is officially known as axillary hyperhidrosis. Studies show that just a handful of injections can reduce underarm sweat for up to TWO years. Um, where do we sign up?
Breast Lift
Are your breasts in need of a pick-me-up? Instead of going under the knife and getting permanent augmentation, some experts have suggested a quick and easy Botox lift. Dr. Zannis says that, “Those looking for a modest improvement are said to be able to temporarily plump their assets thanks to injections into the pectoralis minor chest muscle.”
Depression
The benefits of Botox® may be more than skin deep; two recent studies suggest that it may help alleviate the symptoms of depression. In a study published in the May 2014 issue of the Journal of Psychiatric Research, more than half of participants who had moderate-to-severe depression showed a substantial improvement in depressive symptoms following one injection of Botox® between the brows. This improvement lasts longer than the cosmetic effects, suggesting that the effect may be more than just feeling better about your appearance. Botox® is not approved to treat depression.
Teeth Grinding
Injections of Botox® were used to control involuntary muscle tension and spasms long before it became the go-to wrinkle buster. Dr. Zannis says that, “these neurotoxin injections may weaken the chewing muscles enough to reduce bruxism (teeth grinding) without affecting your ability to chew, talk and smile. Results last about four months. Botox® is not yet approved to treat bruxism.”
Migraine Headache
Botox® is approved by the FDA to treat chronic migraine headaches in adults who have 15 or more headache-days a month, each lasting four hours or more. Studies that led to this indication show that BOTOX®® prevents up to nine headache-days a month (vs seven for dummy injections). Other research hints that the neurotoxin may also help with low cerebrospinal fluid headaches and cluster or "suicide" headaches.
Brow Boost
Much like lines form over time, your brow may also drop or droop. Botox cosmetic treatments can also be used to improve the appearance of the brow. Dr. Zannis explains that, “the treatment essentially freezes the sagging muscles in place and gives the brow more stability. Lifting the brows in this way leaves you with a less tired and younger, fresher appearance.”
Jaw Reduction (off label use)
Botox can be used to perform jaw reduction (commonly called jaw line softening). Injecting Botox into the masseter muscle (the primary muscle used in chewing actions) reduces its overall size; transforming an overly square and masculine appearing jawline into a more feminine oval or heart shape.
Dr. John Zannis is a New Bern, North Carolina board-certified plastic surgeon and best selling author. A graduate of Stanford University and The University of Cincinnati Medical College, he received his formal training in General Surgery and Plastic and Reconstructive Surgery at Wake Forest University in Winston-Salem, North Carolina under the guidance of world-renowned plastic surgeon Dr. Louis Argenta. During this time, he performed over 5,000 surgical procedures and covered all aspects of plastic surgery including cosmetic surgery of the face and body, complex reconstructive procedures of face and body, cleft lip and palate surgery, hand surgery, facial and jaw fracture repair, and reconstruction following massive weight loss. He blends his interests and studies of classical art and symmetry to his surgery practices. Connect with him via twitter@JohnZannisMDor his website www.zannisplasticsurgery.com
Road trips, gas stops, no time for lunch; we’ve all found ourselves at the convenience store for a fast bite on the go. While a bag of chips or chocolate bar may be an option we later regret; there are fast bites that can actually offer some health benefits. Dr. Christopher Calapai a board certified expert in osteopathic medicine specializing in longevity offers some junk food options to consider the next time there’s no time for an actual meal.
Blue M&M’s and Blue Gatorade
Don’t get the blues about all food dyes.From candy to sports drinks, the unnatural colors of foods today can make you cringe at the thought of what’s making them colored. But, not all colored dyes are as bad as you may think. Research done by scientists at the University of Rochester found that Brilliant Blue G (BBG), found in blueM & M’s and blue Gatorade, could help reduce damage from spine injuries. When BBG was injected into lab rats with spinal cord injuries, it sped up their recovery time and ability to walk.
Cheeze Whiz?? No way!!
Fat isn’t always a bad word.The FDA has stated that not only are all trans fats not bad, some are actually good for you. Conjugated Linoleic Acids (CLAs), although high in calories can help fight cancer, weight gain, diabetes and arthritis. It’s hard to believe, but CLAs are found in Cheese Whiz.
Pork Rinds
Just the words pork rinds sound like instant heart attack. However did you know they are a fantastic source of protein? A one-ounce serving of this fried snack has seventeen grams of protein, seven times the amount of found in a serving of potato chips. Plus, 43% of the fat found in pork rinds come from oleic acid, the same healthy fat found in olive oil.
Beer
Some studies have found that beer can actually help increase bone mineral density because it contains silicon, making bones stronger and less likely to fracture. A Harvard University study found that beer could prevent blood clots and reduce the risk of stroke. Italian researchers found that beer can raise HDL, the good cholesterol in your body. Opt for a light beer with fewer calories to avoid that full feeling.
Graham Crackers
They are the next best things to cookies if you’re trying to keep your health in mind. Graham crackers contain much less sugar than regular cookies and are still sweet enough to satisfy a craving. Plus, they are made with flour that undergoes a special milling process, preserving more of the whole wheat than in usual milling.
Popcorn
This is a snack that gets two thumbs up. Popcorn is packed with fiber and polyphenols, which are antioxidants that help to protect us from heart disease and certain cancers. Surprisingly, popcorn has more iron than eggs and spinach! It is also gluten-free, which makes it an option for those with Celiac Disease and other gluten allergies. Lastly, popcorn is mostly air. This means it fills you up, helping to stave off hunger cravings.
Beef Jerky
Forget about the leather-tasting jerky of years past, today’s gourmet jerky is delicious and can be healthy. Beef Jerky, just like its non-dried version of meat, is high in protein, iron and zinc. It, also, contains heart-healthy monounsaturated fats. Be sure to look for natural beef jerky as the newer gourmet styles that are packed with flavor and free of nitrates.
About the Doctor:
Dr. Christopher Calapai, D.O. is an Osteopathic Physician board certified in family medicine, and anti-aging medicine. Proclaimed the "The Stem Cell Guru" by the New York Daily News, Dr. Calapai is a leader in the field of stem cell therapy in the U.S. His stem cell treatments have achieved remarkable results in clinical trials on patients with conditions as varied as Alzheimer's, arthritis, erectile dysfunction, frailty syndrome, heart, kidney and liver failure, lupus, MS and Parkinson's. He has worked with Mike Tyson, Mickey Rourke, Steven Seagal, and Gotham's, Donal Logue; and as a medical consultant for the New York Rangers. Connect with him via twitter @drcalapai or at www.drcal.net
Train It Right Youtube Launch
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Health Smart Financial Services ("Health Smart"), a technology-enabled specialty lender, announced today that it has closed a new senior revolving credit facility with CWB Maxium Financial ("CWB Maxium").
Health Smart's technology platform allows healthcare providers to offer their customers affordable monthly payments for services and products that require private out-of-pocket expense. Health Smart has a rapidly growing base of over 1500 merchant partners who benefit from the company's instant credit approval and paperless transaction capability.
"CWB Maxium is a great partner for our business," said Wayne Pommen, President & CEO of Health Smart. "This new revolving facility replaces our existing facilities and provides us with substantially increased funding capacity to grow our consumer loan portfolio. Combined with the growth equity investment we received from iA Financial Group last month, we are very well capitalized to continue our pace of growth in 2017 and beyond."
"We are pleased to be a funding partner for Health Smart as they capture the point-of-sale financing opportunity in Canada," said Neil Cruickshank, Vice President at CWB Maxium. "Health Smart has tremendous potential to attract quality financial assets. The transaction aligns with our strategy for creative and innovative financing, and supports our growing portfolio in the Canadian financing sector. We look forward to ongoing growth opportunities and collaboration."
About Health Smart: Health Smart Financial Services is a leading Canadian point-of-sale consumer lender focused primarily on the healthcare sector. Using Health Smart's platform, healthcare providers can have their customers approved for affordable monthly payments on-location or remotely using desktop, tablet, or smartphone interfaces. By partnering with Health Smart, merchants provide their customers with greater access to services while growing their sales. Health Smart's major segments include dentistry, fertility, audiology, mobility devices, veterinary services, and cosmetic procedures, in addition to selected segments outside the healthcare sector. Health Smart has approved over $170 million in consumer credit since inception.
About CWB Maxium: CWB Maxium Financial is a CWB Group company and offers creative structured financing that responds directly to the specific needs of each customer. Maxium Financial Services Inc. was founded in 1993, and on March 1, 2016, it became a CWB Group company. Today, the portfolio exceeds $1 billion. With over 35,000 customers, CWB Maxium is earning a reputation for innovative lending solutions coupled with an unparalleled ability to build long-term relationships. Learn more at www.cwbmaxium.com
Morning, Afternoon, and Night... Which Foods Will Do You Right?
If you are not in competition prep or following a weight loss plan from me www.trainitright.com/programs use the tips in this guest post for healthy eating:
Before you grab that morning cup of coffee on an empty stomach, that lunchtime slice of pizza, or indulge in a steak dinner or ice cream while watching TV, understand that what you eat and when you eat it can lead to stomach upset. It can also trigger more severe issues in your gut. On the flip side, there are some foods that when eaten at certain times of day may soothe already existing stomach issues or may even prevent stomach ailments from occurring down the line. We spoke with Dr. Gina Sam Assistant Professor in the Division of Gastroenterology, Department of Medicine at Mount Sinai School of Medicine, New York who offers insights on what and when to eat certain foods for a healthy gut.
Best Bets for Morning
Yogurt
It’s important to start the day with a healthy breakfast that factors in stomach health. Probiotics found in Greek yogurt is ideal as it regulates the growth of harmful bacteria that grown in the digestive tract. Probiotics also keep colon lining healthy as it breaks through gastric acid and gets to the colon. In 2015 a study published in the The Korean Journal of Gastroenterology showed that yogurt might improve intestinal function for those with inflammatory bowel disease. Those who are lactose intolerant can enjoy lactose free yogurt.
Oatmeal
Oatmeal is a great bet for breakfast and can be topped with blueberries another gut friendly food. Oatmeal doesn’t cause acid reflux. It soothes any morning stomach upset and regulates bowel movements.
Fresh Fruit
Honeydew, cantaloupe, and watermelon are great options for those sensitive to reflux. Bananas help restore potassium, electrolytes and normal bowel function, especially if you have diarrhea. Bananas are also high in fiber, which is great for digestion.
The Lunchtime Lowdown
Salads
Eating leafy greens daily is a great for digestion. Lunchtime salads that include grilled salmon; chicken or turkey won’t cause reflux and will be easily digestible throughout the afternoon. If you are sensitive to acid then you will want to avoid onions or tomatoes and for some even the seeds in cucumbers can trigger a bout of stomach cramping. Be careful with lemon juice and vinegar in salad dressings, which can promote reflux. Try adding fennel with arugula and baby spinach along with parsley. Parsley is known to help digestion and settles the stomach.
Kimchi
This delicious Korean coleslaw is made primarily with cabbage, which promotes the growth of healthy bacteria in the colon. Also cabbage helps to eliminate waste regulating bowl movements. Home made sauerkraut is also a delicious option but be mindful if you are sensitive to spicy foods. This is why it is best to make your own so you can regulate the amount of spice.
Mediterranean Plates
Lunchtime is optimal for grilled veggies, legumes such as lentils with olive oil along with grilled fish or chicken. Preparing a plate of various whole grains, cauliflower, carrots, figs and pears are all great sources of fiber for the mid day.
A Digestible Dinner
You really want to focus on ease of digestion at dinnertime. Foods that are high fat
can overwhelm the stomach, resulting in acid reflux and heartburn. Steatorrhea or pale colored stool is excess fat in the feces. People with IBS fare better when they avoid high fat foods. That said here are some options for a healthy gut.
Grilled Fish
Cold-water fish such as salmon, halibut, or tuna when grilled in olive oil are full of omega-3 fatty acids, which can address any inflammation in the digestive tract. According to a 2014 study featured in the World Journal of Clinical Cases, omega-3’s were sites as being beneficial to those with ulcerative colitis.
Grilled Chicken with Couscous or Brown Rice
Chicken another lean meat that offers protein and is easy to digest goes great with couscous or brown rice especially if you tend to get acid reflux after late meals. Another option for a side dish is guacamole or avocado slices with lime. Artichokes also feed the good bacteria in your gut as does asparagus and lentils.
Stomach Friendly Snacking
When it comes to snacking there are several options you can reach for. Granny smith apples with almond butter, baby carrots and hummus, hallowed out cucumber and cottage cheese, kale and zucchini chips and assorted nuts (not peanuts) are all healthy and good for the gut.
You know your body best. Pay close attention to what agrees with you at varying times of the day and if you notice changes in how you take to certain foods see your doctor.
About Dr. Gina Sam:
Dr. Gina Sam, MD/MPH is an Assistant Professor in the Division of Gastroenterology, Department of Medicine at Mount Sinai School of Medicine, New York. She is the Director of the Mount Sinai Gastrointestinal Motility Center specializing in achalasia, gastroesophageal reflux, functional disorders, irritable bowel syndrome, gastroparesis, and anorectal disorders including pelvic floor dyssnergia and fecal incontinence.
In addition, she does practice General Gastroenterology including colon cancer screening with colonoscopy. She also has a special interest in Women's Health Issues.
Dr. Sam graduated from Tufts University School of Medicine with her medical degree and her Master's in Public Health with a concentration in Community Health in 2003. She has established the Mount Sinai Gastrointestinal Motility Center at Mount Sinai Medical Center providing a multidisciplinary approach to motility and Functional gastrointestinal disorders.
World's Smallest Pacemaker Licenced for Canadian Patients
The Medtronic Micra Transcatheter Pacing System is the first leadless pacemaker licenced in Canada and the worlds smallest pacemaker. (CNW Group/Medtronic Canada)
The Medtronic Micra™ Transcatheter Pacing System (TPS) is the First Leadless Pacemaker Licenced in Canada
Medtronic Canada, a subsidiary of Medtronic plc (NYSE:MDT), today announced it has received a Health Canada licence for the world's smallest pacemaker, the Medtronic Micra™ Transcatheter Pacing System (TPS). The Micra TPS is the first Health Canada licenced product with miniaturized pacing technology. It is cosmetically invisible and small enough to be delivered through a catheter and implanted directly into the heart - providing a safe alternative to conventional pacemakers without the need for cardiac wires (leads).
Comparable in size to a large vitamin capsule, the Micra TPS is attached to the heart with small tines and delivers electrical impulses that pace the heart through an electrode at the end of the device. Unlike traditional pacemakers, the Micra TPS does not require leads or a surgical "pocket" under the skin, and there are no visible signs of the device. The Micra TPS responds to patients' activity levels by automatically adjusting therapy.
Micra TPS is the first and only leadless pacing system to be licenced for both 1.5 and 3 Tesla (T) full-body magnetic resonance imaging (MRI) scans, providing patients with continued access to these advanced imaging diagnostic procedures.
The Micra design incorporates a retrieval feature to enable repositioning if needed; however, the device is designed to be left in the body. For patients who need more than one device, the miniaturized Micra TPS was designed with a feature that enables it to be permanently turned off so it can remain in the body and a new device can be implanted without risk of electrical interaction.
In November 2015, data from the Medtronic Micra TPS Global Clinical Trial, which included two Canadian centres, were published in the New England Journal of Medicine and presented during a late-breaking Special Report at the American Heart Association Scientific Sessions. These data showed the Micra TPS was successfully implanted in 99.2 percent of patients, there were no (0) dislodgements, and the system met its safety and effectiveness endpoints with wide margins at six month follow-up.
Data presented in August 2016 at the European Society of Cardiology (ESC) Congress showed that the risk for major complications with the Micra TPS remained consistently low, with 96 percent of patients experiencing no major complications through 12 months follow-up (95 percent confidence interval, 94.2 percent-97.2 percent, P<0.0001). The Micra TPS reduced the risk of major complications by nearly half (48 percent; hazard ratio = 0.52, P=0.001) compared to conventional systems and the risk was lower across all patient sub-groups, whether measured by age, sex or comorbidity (all hazard ratios < 1.0).
The overall reduction in major complications with the Micra TPS was associated with a 47 percent decrease (p=0.017) in the risk of hospitalization and 82 percent (p<0.001) reduction in risk of system revisions (meaning extraction, repositioning or replacement) compared to conventional pacing systems.
"Dating back to the development of the first external battery operated pacemaker more than 60 years ago, Medtronic has a long history of collaborating with clinicians to better understand the needs of patients, and then innovating new products to meet those needs," said Michael Blackwell, director of the CardioVascular Group at Medtronic Canada. "We are thrilled to be the first to introduce a transcatheter pacemaker to patients in Canada, and we're looking forward to working with physicians and educating implanters to extend the positive results of our global clinical trial experience to even more patients."
The Micra TPS was awarded CE Mark in April 2015 and FDA approval in April 2016. It is intended for use in patients who need a single-chamber pacemaker. The device was designed to allow patients to be followed by their physicians and send data remotely via the Medtronic CareLink™ Network; remote monitoring of Micra devices is expected to be available in the near future.
In collaboration with leading clinicians, researchers and scientists worldwide, Medtronic offers one of the broadest ranges of innovative medical technology for the interventional and surgical treatment of cardiovascular disease and cardiac arrhythmias. The company strives to offer products and services that deliver clinical and economic value to healthcare consumers and providers around the world.
New compound shows promise in treating multiple human cancers
A new compound, discovered jointly by international pharmaceutical company Servier, headquartered in France, and Vernalis (R&D), a company based in the UK, has been shown by researchers at the Walter and Eliza Hall Institute and Servier to block a protein that is essential for the sustained growth of up to a quarter of all cancers.
The research presents a new way to efficiently kill these cancerous cells and holds promise for the treatment of blood cancers such as acute myeloid leukaemia, lymphoma and multiple myeloma, as well as solid cancers such as melanoma and cancers of the lung and breast. It is published online today in the journal Nature.
The Servier compound - S63845 - targets a protein of the BCL2 family, called MCL1, which is essential for the sustained survival of these cancer cells.
Institute scientist Associate Professor Guillaume Lessene, who led the Walter and Eliza Hall Institute's research team in Melbourne, Australia, said the work provided the first clear preclinical evidence that inhibiting MCL1 was effective in targeting several cancer types.
"MCL1 is important for many cancers because it is a pro-survival protein that allows the cancerous cells to evade the process of programmed cell death that normally removes cancer cells from the body," Associate Professor Lessene said. "Extensive studies performed in a variety of cancer models have shown that S63845 potently targets cancer cells dependent on MCL1 for their survival."
The institute team of Associate Professor Lessene worked with haematologist Associate Professor Andrew Wei and Dr Donia Moujalled from The Alfred Hospital and Servier scientists, to demonstrate that not only was S63845 effective against several cancer types, but that it could also be delivered at doses that were well tolerated by normal cells.
Dr Olivier Geneste, Director of Oncology Research at Servier, said: "This preclinical research and the identification of drug candidates confirm the potential of MCL1 as a therapeutic target in cancers. S63845 was discovered through collaboration with the fragment and structure based discovery expertise at Vernalis. As part of the ongoing Servier / Novartis collaboration on this target class, clinical development of a MCL1 inhibitor should be launched in the near future."
Associate Professor Lessene said the research provided further evidence of the usefulness of a new class of anti-cancer drugs called BH3 mimetics. "BH3 mimetics inhibit a group of proteins known as the 'pro-survival BCL-2 proteins'," he said. "MCL1 is a member of this protein family, and inhibiting it activates the process of programmed cell death. Walter and Eliza Hall Institute researchers revealed the role of BCL-2 in cancer more than 28 years ago and the essential role of MCL1 for the survival of malignant cells four years ago."
The research was supported through a research collaboration with Servier and through funding from the National Health and Medical Research Council of Australia, the Leukemia and Lymphoma Society (US), Cancer Council Victoria, the Kay Kendall Leukemia Fund, Victorian Cancer Agency, Australian Cancer Research Foundation, the Victorian Government Operational Infrastructure Scheme and the estate of Anthony Redstone.
The Walter and Eliza Hall Institute is the research powerhouse of the Victorian Comprehensive Cancer Centre, an alliance of leading Victorian hospitals and research centres committed to controlling cancer.
About Servier
Servier is an international pharmaceutical company governed by a non-profit Foundation and headquartered in France. With a strong international presence in 148 countries and a turnover of 3.9 billion euro in 2015, Servier employs over 21,200 people worldwide. Corporate growth is driven by Servier's constant search for innovation in five areas of excellence: cardiology, oncology, metabolism, neuropsychiatry and rheumatology, as well as by its activities in high quality generic drugs. Being completely independent, the Group reinvests 25% of Servier's products turnover in Research and Development, and all its profits in its growth.
Becoming a key player in oncology is part of Servier's long-term strategy. Currently, there are nine molecular entities in clinical development in this area, targeting gastric and lung cancers and other solid tumors, as well as various leukemias and lymphomas. This portfolio of innovative cancer treatments is being developed with partners worldwide, and covers different cancer hallmarks and modalities, including cytotoxics, proapoptotics, targeted, immune and cellular therapies.
BELLY BLOATING BUSTERS:
Avoiding Foods That Make You Look & Feel Fat for Every Life Occasion
When planning for a fun get-together with friends everything goes through your mind, from your wardrobe to jewelry and make-up. What many of us don’t plan for, however, is our meals. Eating the wrong foods before an event can sabotage your beauty plan. Certain foods can give your gut an instant bloat that looks and feels awful. However, there is a solution to this dilemma. Instead of skipping dinner to squeeze into your LBD or grabbing bagels for a quick morning bite, there are belly bloat busters. Dr. Christopher Calapai, D.O. is an Osteopathic Physician board certified in family medicine and anti-aging medicine. Here are some of his suggestions:
For a girl’s night out: Don’t be afraid to have a large meal beforehand (large meaning more than just a PB&J). If you are planning for an active night, whether dancing, bowling or party hopping, you will need the fuel. Dr. Calapai has created the perfect meal for this situation:
- 1 grilled chicken breast (approx 4 oz)
- 1/2 cup cooked brown rice and lentils
- 1 cup steamed string beans
This combo will fill you up without weighing you down, and will give you the energy you need to dance the night away!
For a dinner- date: You’re wearing a stunning new BCBG dress that already had to be zipped up by your roommate. When you’re at the restaurant with your guy refrain from ordering a salad to make it look like you’re being healthy. All the veggies in the salad will actually cause your stomach to bloat more. Dr. Calapai advises that a fish dish with one side of grilled veggies is the way to go! “Wild Salmon is jam-packed with heart healthy vitamins and omega 3 fatty acids. If Salmon is not an option, mackerel, sea bass and lemon sole are all good options as well. As for the veggies, try to steer clear of cruciferous veggies (such as cauliflower, broccoli) that can cause bloating. Instead opt for grilled zucchini, asparagus, or carrots - which will keep your tummy tamed!”
For a day at the beach: It’s finally getting warm out and you can take that bathing suit out of hiding. If you’re going to the beach you need a healthy, energizing meal to get you through the morning but you don’t want it to show in your stomach. You’re probably thinking that the easiest thing to eat before you head out is some Special K with skim milk. It’s low in calories after all, right? It doesn’t matter how low-cal it is, the dairy and multi-grains will expand in your intestines, causing your gut to stick out. Instead of cereal, Dr. Calapai has an awesome recipe for oatmeal pancakes. Take 1/2 cup raw oats, 3 egg whites, 1/2 apple, and a dash of cinnamon and throw in a blender to create the pancake mix. This high fiber non-fat breakfast choice offers whole grain fiber plus additional fiber from the apple, and protein from the egg whites. It's a great filling way to start the day, and will not create any abdominal gas or bloating, so you can go bikini-bare with ease!
For an afternoon luncheon: Eating a well-balanced lunch is essential for boosting energy and productivity; giving you power over that mid-day slump and keeping your metabolism active. A lot of times people want to skip lunch in hopes of losing weight and grab an energy drink to keep them going. This is so bad! The carbonation from an energy drink will make you more bloated then a light lunch. Dr. Calapai says, “For a mid-day luncheon, your best bet is a salad chock-full of fresh veggies and greens, and topped with a piece of grilled fish, low-fat tuna salad, or fresh turkey breast slices. Throw a few walnuts or almonds on top and dress with a low fat/low sugar dressing, to finish off your delicious salad creation!”
Before Sex: Luckily, you can eat your dinner or dessert (or both, on good dates) and enjoy sex too. Just lay off the foods that can trigger digestive issues, a real problem if you have a sensitive stomach or suffer from date-related anxieties, which can amplify digestive issues, according to Dr. Calapai. An 8-ounce piece of meat could trigger gas that's particularly foul-smelling. "Gas associated with red meat is more odorous because of chemicals it produces in the colon," Dr. Calapai explains. That's because when you overeat protein, it goes straight to the colon for fermentation where it creates some seriously offensive byproducts. A safer bet is salad greens, cucumbers, tomatoes, bell peppers, mushrooms. Instead of a Margarita drink: Tequila straight up, or wine (a safer bet). This way, you're only up against naturally occurring sugars.
For traveling days: These days airports are getting bigger and so are the food courts. It’s tempting to give in to the convenience of fast travel food, but the combination of a high-sodium smorgasbord and air travel equals a very bloated body from head to toe. You absolutely must resist because there are better options. Eat before you leave for the airport. Dr. Calapai suggests packing your carry-on with fruits, veggies, and granola bars. Believe it or not these are available at kiosks. Also, avoid the beverage service on board. Stick to water, you will have a happier flight and feel revived upon arriving at your destination!
Dr. Christopher Calapai D.O.
Anti-Aging Physician and "The Stem Cell Guru
Dr. Christopher Calapai, D.O. is an Osteopathic Physician board certified in family medicine, anti-aging medicine and chelation therapy. Proclaimed as the "The Stem Cell Guru" by the New York Daily News, Dr. Calapai is a leader in the field of stem cell therapy in the U.S.
His stem cell treatments have achieved remarkable results in clinical trials on patients with conditions as varied as Alzheimer's, arthritis, erectile dysfunction, frailty syndrome, heart, kidney and liver failure, lupus, MS and Parkinson's.
Dr. Calapai started his practice in New York City in 1986 and for over 25 years he has hosted nationally syndicated radio shows, including his two weekly call-in shows on WABC 770-AM, where he offers health and medical advice. He has a show on Saturday morning 8-9am and Sunday evening from 6-7pm. He has consulted with numerous high-profile individuals including Mike Tyson, Mickey Rourke, Steven Seagal, and Fox series Gotham's, Donal Logue and worked as a medical consultant for the New York Rangers hockey team as well as various modeling agencies.
Dr. Calapai received his medical degree from New York College of Osteopathic Medicine and he consults in Manhattan with practices on Long Island, in East Meadow and Plainview. He has appeared on News12 and in the pages of 25A Magazine and Social Life Magazine.
He is the author of E-books Heavy Metals and Chronic Disease, Reverse Diabetes Forever! Seven Steps to Healthy Blood Sugar, Top Ten Supplements You Can't Live Without, and Glorious Glutathione. Learn more about Dr. Calapai on his website, www.drcal.net.
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