New Book Empowers, Challenges Gay Men to Own their Truths
Seattle, WA, February 16, 2021 — Acceptance of homosexuality and same-sex marriage has increased dramatically over the past two decades, but this expanding approval from society at large does nothing to negate the internal struggles that most gay men face — particularly young gay men — in response to familial and societal expectations. Their road toward self-discovery is long and arduous, pockmarked by generational biases and homophobic messaging. An introspective tug-of-war wages each time a new milestone approaches, and with no clear path in sight, many gay men simply find themselves in a proverbial roundabout, trapped in an endless loop of no-win situations.
“If we don’t live honestly and openly, we won’t have the skills, wisdom, or relationships necessary to manifest our dreams,” says Britt East, author of A Gay Man's Guide to Life: Get Real, Stand Tall, and Take Your Place. “But when we do come out, we must confront the full force of societal homophobia, and consider a variety of questions.”
Among those uncertainties are how to create a family without mimicking the norms of a straight society; how to overcome internalized homophobia and cultivate sustainable gay friendships; and, in a world of hook-up apps and disposable relationships, how to find lasting love.
AGay Man’s Guide to Life, which ispart memoir and part inspirational guidebook, addresses these crucial topics and many others, through the lens of a gay man, for gay men everywhere.
Britt candidly and vividly shares his own traumatic, personal journey, and uses his experiences and insights to inform an approachable, no-nonsense path to help gay men set down excuses and get to the business of improving the most important facets of their lives, including body, mind, spirit, career, family and more. He offers hope and support, giving readers the sense of family that perhaps they never had. AGay Man’s Guide to Life is not comprised ofnew-age mumbo jumbo or wishy-washy self-help jargon. It is about real work focused on real results to help members of the gay community.
At its core, AGay Man’s Guide to Life is a manual for personal growth and development, with plenty of pragmatic advice to challenge and inspire gay men to uncover their true selves and live their best lives.
Britt East is an author and speaker who uses his experience, strength and hope to challenge and inspire change-oriented gay men to get down to the business of improving their lives. With over two decades of personal growth and development experience in a variety of modalities, such as the 12 Steps, Nonviolent Communication, yoga, meditation, talk therapy and the Hoffman Process, Britt is committed to building a personal practice of self-discovery that he can then share with gay men everywhere. He lives in Seattle with his husband and their crazy dog.
For more insights from the author, please visit www.britteast.com, or follow him on Instagram (@britteast); Twitter (@britteast); or Facebook (@brittdawsoneast).
A Gay Man's Guide to Life: Get Real, Stand Tall, and Take Your Place
Publisher: Houndstooth Press
ISBN-10: 1544509227
ISBN-13: 978-1544509228
Available from Amazon.com, BN.com, Apple Books and many online outlets
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Feeling Forwards: Learn How to Harness the Infinite Energy of Your Emotions
"Feeling Forwards helps you find the power within to overcome unbelievable challenges and take a quantum leap forwards." — TONY ROBBINS
New York, NY, March 16, 2021 — Everything you need to transform your life is already within you, asserts bestselling author and personal reinvention coach Elizabeth Gould. Her empowering new book, Feeling Forwards: How to Become the Person Who Has the Life You Want, can help you say farewell to negative habits, release painful beliefs and tap into your full potential by harnessing the infinite energy generated by your emotions.
“Feeling Forwards is a thinking and feeling revolution. It’s not about writing to-do lists or visualizing every step toward a goal,” Elizabeth says. “Feeling Forwards is about living life as the complete person you’ve forgotten you already are and not as the person who’s just waiting to shine.”
The first half of Feeling Forwards is a fascinating deep-dive into the science proving the true power of our emotions, enabling them to travel forward and backward in time, influence pre-programmed computer outcomes, reverse aging, impact crime rates, fast-track personal reinvention and much more. After understanding the effects that our emotions can truly have on our lives, Elizabeth offers practical applications of the strategies in Feeling Forwardsusing real-life examples of those who’ve successfully integrated the principles into their lives.
Woven throughout are Elizabeth’s candid, personal stories of embracing these principles to thrive through several life-threatening events and dramatic personal upheavals.
The result is a refreshingly relatable, actionable guide to help you create the life you genuinely want to live. Feeling Forwards teaches you how to become the person who has the life you want … today. As Elizabeth reveals, “Today is the past of your future.”
About the Author
A bestselling author and founding member of Randi Zuckerberg’s global leadership school at the Zuckerberg Institute, Elizabeth Gould experiences the joy of working with people around the world to unlock their potential. She has spent decades interviewing thousands of successful professionals to understand how they behave to achieve what they want. Her work is endorsed by world-renowned life and business strategist, Tony Robbins. Feeling Forwards is her third book.
Medicago and GSK start Phase 3 trial of adjuvanted COVID-19 vaccine candidate
Trial to enroll up to 30,000 volunteers worldwide
Fast Track designation granted by US FDA
Feasibility study initiated of a vaccine candidate to address emerging variants
QUEBEC CITY and LONDON, March 16, 2021 /CNW/ - Medicago, a biopharmaceutical company headquartered in Quebec City and GlaxoSmithKline (GSK), are pleased to announce the start of Phase 3 clinical testing of Medicago's plant-derived COVID-19 vaccine candidate in combination with GSK's pandemic adjuvant, as part of the ongoing Phase 2/3 study. Medicago received approval from Canadian and US regulatory authorities to proceed with enrollment of healthy adults in the Phase 3 portion of the trial based on positive interim Phase 2 results. In parallel, Medicago has also initiated a feasibility study of a vaccine candidate to address the emerging COVID-19 variants.
"We are pleased to take the significant step of initiating the Phase 3 clinical trial at sites around the world," said Takashi Nagao, CEO and President of Medicago. "This brings us one step closer to delivering an important new COVID-19 vaccine and contributing to the global fight against the pandemic along with our partner GSK."
Thomas Breuer, Chief Medical Officer, GSK Vaccines said, "This advance to late stage clinical testing further reinforces our confidence in the adjuvanted vaccine candidate's potential to make a difference in the continued fight against COVID-19. We look forward to sharing results later this year."
Medicago's plant-derived vaccine candidate against COVID-19 uses Coronavirus-Like-Particle (CoVLP) technology with the vaccine composed of recombinant spike (S) glycoprotein expressed as virus-like-particles (VLPs) co-administered with GSK's pandemic adjuvant. Two doses of 3.75 micrograms of CoVLP are administered 21 days apart.
The vaccine candidate, in combination with the pandemic adjuvant, was granted Fast Track designation by the U.S. Food and Drug Administration (FDA) on February 17, 2021. Fast Track designation allows the FDA to expedite the development and review of new medicines and vaccines intended to treat or prevent serious conditions and address an unmet medical need.
"The FDA's decision to grant Fast Track designation for Medicago's vaccine candidate will help us expedite our efforts to bring the first plant-derived COVID-19 vaccine to market, subject to regulatory approval," said Carolyn Finkle, Chief Operating Officer of Medicago. "We are grateful to the FDA and look forward to continuing to work with them as we move forward in our clinical trials, planned application for Emergency Use Authorization, and eventual vaccine licensure application process."
The Phase 3 portion of the study is an event-driven, randomized, observer-blinded, placebo-controlled, two-way cross-over design that will evaluate the efficacy and safety of the adjuvanted CoVLP formulation, compared to placebo. The study will enroll up to 30,000 subjects initially composed of healthy adults (18y to 65y), followed by elderly adults (65y+) and adults with comorbidities. The trial will take place in 10 countries pending regulatory approvals, starting with Canada and the United States, and will enroll males and females from ethnically and racially diverse populations.
The Phase 2 portion of the trial is approaching completion and results are expected to be made publicly available in April 2021.
About Medicago
Medicago is on a mission to improve global public health using the power of plants. Founded in 1999 with the belief that innovative approaches and rigorous research would bring new solutions in healthcare, Medicago is a pioneer in plant-derived therapeutics. We are proudly rooted in Quebec, with manufacturing capacity in both Canada and the US. Our passionate and curious team of over 450 scientific experts and employees are dedicated to using our technology to provide rapid responses to emerging global health challenges, and to advancing therapeutics against life-threatening diseases worldwide.
GSK is a science-led global healthcare company with a special purpose: to help people do more, feel better, live longer. For further information please visit www.gsk.com/about-us.
GSK is collaborating with companies and research groups across the world working on promising COVID-19 vaccine candidates through the use of our innovative vaccine adjuvant technology. The use of an adjuvant is of particular importance in a pandemic situation since it may reduce the amount of vaccine protein required per dose, allowing more vaccine doses to be produced and therefore contributing to protecting more people. GSK does not expect to profit from COVID-19 vaccines during the pandemic phase and will invest any short-term profit in coronavirus related research and long-term pandemic preparedness, either through GSK internal investments or with external partners.
SOURCE Medicago
Amgen announces Artificial Intelligence (AI) Partnership with Mila
MONTREAL, March 16, 2021 /CNW/ - Amgen announced today that it has entered into a multi-year partnership with Mila – Quebec Artificial Intelligence Institute. One of the world's leading biotechnology companies, Amgen uses cutting-edge science and technology to discover and develop innovative therapeutics, and AI is currently deployed in several of its R&D and manufacturing activities. This new partnership will permit Amgen to expand its knowledge of AI and deep learning by interacting and engaging with experts in Mila's unique ecosystem, both virtually and (eventually) on the Mila campus in Montreal. This announcement was made during Effervescence 2021, an international virtual gathering of scientists, entrepreneurs and industry professionals from the life sciences and health technology sectors in the presence of the Quebec Minister of Economy and Innovation, Pierre Fitzgibbon.
"We are very happy to have signed this partnership with Mila," said Philip Tagari, Amgen's Vice President of Research, Therapeutic Discovery. "AI is a powerful and innovative tool, and is affecting every step of drug discovery, from better understanding the biological mechanisms of disease and designing molecules to predicting clinical responses and safety profiles. Mila is recognized as being at the global forefront in deep learning and we are excited by the opportunity of combining Mila's world-renowned expertise with Amgen's use of AI in drug development, as well as the possibility of engaging with a uniquely talented group of young AI professionals," he added.
"In Mila we see a strong example of Quebec's leadership in AI and in healthcare innovation," stated Brian Heath, Vice President and General Manager of Amgen Canada. "We are eager to explore the synergies between Mila's expertise and Amgen's mission to serve patients as we continue to develop the next generation of innovative medicines."
"More and more of Mila's world-class AI experts have research interests at the intersection of AI and life sciences, recognizing the incredible potential of AI-driven solutions for healthcare and pharmaceutical R&D activities," explained Stéphane Létourneau, Executive Vice President at Mila. "Meaningful collaborations, such as this newly established partnership between Amgen and Mila, are essential in order to maximize the full potential of AI for health innovation. We are excited to welcome Amgen within our scientific community and to consolidate our efforts towards advancing and accelerating drug discovery and development."
About Amgen Canada As a leader in innovation, Amgen Canada understands the value of science. With main operations located in Mississauga, Ontario's vibrant biomedical cluster, and its research facility in Burnaby, B.C., Amgen Canada has been an important contributor to advancements in science and innovation in Canada since 1991. The company contributes to the development of new therapies and new uses for existing medicines in partnership with many of Canada's leading healthcare, academic, research, government and patient organizations. To learn more about Amgen Canada, visit www.amgen.ca.
About Mila
Founded by Professor Yoshua Bengio of the Université de Montréal, Mila is a research institute in artificial intelligence which rallies over 700 researchers specializing in the field of deep learning. Based in Montreal, Mila's mission is to be a global pole for scientific advances that inspires innovation and the development of AI for the benefit of all. Mila is a non-profit organization recognized globally for its significant contributions to the field of deep learning, particularly in the areas of language modelling, machine translation, object recognition and generative models. For more information, visit Mila.quebec.
SOURCE Amgen Canada
Canadian seniors re-evaluating aging priorities in light of pandemic
New research from Home Instead shows seniors more committed to aging at home, more apprehensive about long-term care
TORONTO, March 16, 2021 /CNW/ - As we reach the one year mark of COVID-19 lockdowns, and as vaccine rollout ramps up, many are considering how life will be different post-pandemic. New research from Home Instead, Inc.1 confirms that Canadian seniors – the demographic hardest-hit by the pandemic – are re-evaluating what's important as they age.
Approximately two-thirds (69 per cent) of Canadian seniors surveyed say the pandemic has made them more committed to staying in their homes as they get older, and 68 per cent say the pandemic has made them apprehensive about living in a long-term care home. The Coronavirus' impact on the desire to age at home is even more prevalent in Canada than among U.S. seniors (69 per cent in Canada vs. 57 per cent in the U.S.), as are pandemic-induced concerns about long-term care homes (68 per cent in Canada vs. 56 per cent in the U.S.).
"The pandemic has been absolutely devastating for our senior populations, but if there's a silver lining, it's that we've been given an opportunity to reimagine how we care for seniors in the future," said Dr. Lakelyn Hogan, PhD, gerentologist and caregiver advocate for Home Instead. "As we rebuild, it's clear we need to work harder to provide safe, viable opportunities for seniors to age how they wish to age – where ever they call home."
____________________________
1 Home Instead, Inc., franchisor of the Home Instead Senior Care network, fielded an online survey of 1,000 Canadian seniors aged 65 and older, including 495 ages 75 and older. The survey was fielded between February 9 and 16, 2021.
According to Home Instead's research, the pandemic hasn't just changed how seniors plan to age, it's changed how they connect to the world around them. More than half (52 per cent) of Canadian seniors are more comfortable using technology since the start of the pandemic, and 35 per cent are more comfortable using technology to help with their care at home moving forward. This comfort with technology is critical for ensuring families and care providers can design care plans that enable a senior to age safely in the place they call home.
Technology is also critical to help ensure seniors stay connected to their loved ones. Just under half (46 per cent) of Canadian seniors are using video calling more or for the first time since the start of the pandemic, and of those using communications technology more frequently, 40 per cent are reporting deeper connections with their loved ones and 72 per cent of seniors say they'll continue to use technology to communicate after the pandemic is over.
"Isolation and loneliness are serious threats to seniors' mental and physical wellbeing, and will be long after the pandemic has ended." said Hogan. "Connecting with your senior loved ones regularly – whether virtually or in person – and spotting signs of loneliness early can increase the likelihood that a senior can continue to age safely at home longer."
Despite the challenges of the last year, the majority of Canadian seniors remain hopeful for the next 12 months (62 per cent).
For more information about how to keep your senior loved one safe at home during the pandemic and beyond, and to download a home safety checklist, visit homeinstead.ca.
ABOUT HOME INSTEAD The Home Instead® franchise network provides personalized care, support and education to enhance the lives of aging adults and their families. Today, the network is the world's leading provider of in-home care services for seniors, with more than 1,200 independently owned and operated franchises that provide more than 80 million hours of care annually throughout Canada, United States and 13 other countries. Local Home Instead offices employ approximately 90,000 CAREGiversSM worldwide who provide basic support services that enable seniors to live safely and comfortably in their own homes for as long as possible. Home Instead franchise owners partner with clients and their family members to help meet varied individual needs. Services span the care continuum – from providing personal care to specialized Alzheimer's care and hospice support. Also available are family caregiver education and support resources. Visit HomeInstead.ca. Connect with us on Facebook and Twitter.
SOURCE Home Instead
Surgery should remain as mainstay of treatment for acute uncomplicated appendicitis
Monday, 15 March 2021: An RCSI study conducted in Beaumont Hospital in Dublin has found that surgery, rather than antibiotics-only, should remain as the mainstay of treatment for acute uncomplicated appendicitis.
Published in the Annals of Surgery and led by researchers from the RCSI University of Medicine and Health Sciences, the study entitled the COMMA trial (Conservative versus Open Management of Acute uncomplicated Appendicitis) examined the efficacy and quality of life associated with antibiotic-only treatment of acute uncomplicated appendicitis versus surgical intervention. The results revealed that antibiotic-only treatment resulted in high recurrence rates and an inferior quality of life for patients.
Acute uncomplicated appendicitis is a commonly encountered acute surgical condition. Traditional management of the condition has involved surgery to remove the appendix (appendectomy). Antibiotic-only treatment has emerged as a potential alternative option that could offer benefits to patients and hospitals, such as a faster recovery, less scaring, less pain, a better quality of life for patients and reduced demand on operating theatres. There has been a reluctance to adopt antibiotic-only treatment due to previous research that has shown wide variability in failure rates and a lack of evidence regarding the impact on quality of life for patients.
In this research, 186 patients with radiological evidence of acute, uncomplicated appendicitis were randomised to two groups. One group received antibiotic-only treatment and patients in the other group were treated with surgery. Patients in the surgery group underwent a laparoscopic appendectomy. In those treated with antibiotics-only, intravenous (IV) antibiotics were administered until there was an improvement in a patient’s signs and symptoms and this was followed by five days of oral antibiotics.
In the weeks and months following treatment, patients were followed up with questionnaires including a quality of life questionnaire at 1 week, 1 month, 3 months and 12 months. At these points, the patient’s pain score, need for additional sick leave, surgical site infections and the development of recurrent appendicitis were recorded.
The results from the antibiotic-only group demonstrated that 23 patients (25%) experienced a recurrence of acute appendicitis within one year. In the quality of life questionnaires, it was found that patients in the surgery group experienced a significantly better quality of life score compared with the antibiotic-only group.
Professor Arnold Hill, Head of School of Medicine and Professor of Surgery, RCSI, said: ‘Antibiotic-only treatment of acute uncomplicated appendicitis has been proposed as an alternative less-invasive treatment option for patients. The COMMA Trial set out to establish if antibiotic-only treatment could replace surgery in some cases, which could offer many benefits for patients and hospitals alike. The results indicate that the treatment protocols should not change. Surgery will deliver the best outcomes for patients in terms of quality of life and recurrence and therefore should remain as the mainstay of treatment for acute uncomplicated appendicitis.’
The study was carried out by researchers from RCSI and Beaumont Hospital Dublin. The research was supported by RCSI.
ENDS
About RCSI University of Medicine and Health Sciences
Ranked number one globally for Good Health and Well-being in the Times Higher Education (THE) University Impact Rankings 2020, RCSI University of Medicine and Health Sciences is an international not-for-profit university, with its headquarters in Dublin.
RCSI is exclusively focused on education and research to drive improvements in human health worldwide. It is among the top 250 universities worldwide in the World University Rankings (2020) and its research is ranked first in Ireland for citations. RCSI has been awarded Athena Swan Bronze accreditation for positive gender practice in higher education.
Visit the RCSI MyHealth Expert Directory to find the details of our experts across a range of healthcare issues and concerns. Recognising their responsibility to share their knowledge and discoveries to empower people with information that leads them to better health, these clinicians and researchers are willing to engage with the media in their area of expertise.
Oldest Outdoor Group in US Challenges You to Spend 2 Hours Outside Each Week—6 Survival Tips
New York City, NY, March 15, 2021 — This winter, the Appalachian Mountain Club (www.outdoors.org), the oldest outdoor group in the United States, challenges you to spend two hours of outdoor exercise every week (social distancing, of course). Even though the entire country is experiencing two fewer weeks of snow cover compared to 100 years ago, wherever you live in America, getting outdoors regularly will provide mental benefits as well as physical ones. Despite the fact winter may be fundamentally shifting, AMC’s Colby Meehan, Leadership Training Manager, reveals six survival tips for thriving, surviving and basking in everything Mother Nature has to offer during winter 2021:
1. Plan your adventure: Avoid a 911 emergency by mapping out your exact route, choosing an alternate route for emergencies and calculating how long your roundtrip excursion will be. Make a trip plan and bring things like high-energy snacks and water for a more enjoyable day out.
2. Find the forecast:Check the forecast before you go by listening/watching/reading your favorite weather predictions in advance. This will help you prepare for the appropriate climate while you are out and about. Observe weather changes as they emerge and change your plan for the day as needed to avoid severe weather.
3. Dress appropriately: Carry the right gear based on the weather predictions to pack appropriately. Understanding how to layer for winter makes a world of difference. Avoiding fabrics like cotton and opting for ones like polyester or wool can turn a miserable, risky outing into a pleasant one. For good measure, take extra pairs of gloves, mittens and socks for especially cold temperatures.
4. Build a safe and protected outdoor living space: To guarantee a fun and safe small gathering under COVID conditions, you can create the perfect outdoor living space on a variety of different budgets. Fire pits are affordable, secure heat sources, and waterproof seating offers comfort while keeping you dry. Prep meals in advance so you can focus on fun and enjoy your time outside. Maintain social distancing guidelines (at least 6 feet apart) from other campsites when making your own.Finally, remember the Leave No Trace principles when you leave, which ask you to carry out anything that does not belong in nature.
5. Outdoor recreation and wellness: Winter brings a multitude of activities and sports. It can be as advanced as snowboarding and skiing; but you can also have a blast without snow by jogging, picnicking or hiking. Studies show that spending at least 120 minutes outdoors every week boosts your well-being.
6. Explore the city outdoors: City dwellers also have ways to revel outside during COVID. Whether you decide to walk around your neighborhood for 20 minutes a day, take up birdwatching in a local park for an afternoon or even study the surrounding architecture, time spent outside is good for you.
The mission of the Appalachian Mountain Club is to foster the protection, enjoyment and understanding of the outdoors. They envision a world where our natural resources are healthy, loved and always protected, and where the outdoors occupies a place of central importance in every person’s life. For more information, please visit www.outdoors.org.
World Water Day Brings Awareness to Global Water Crisis as COVID-19 Emphasizes Need for Urgent Action
Alberta-based organization CAWST is calling on Albertans to help ensure global access to safe water, sanitation and hygiene
CALGARY, AB, March 15, 2021 /CNW/ - With World Water Day approaching on March 22, the Centre for Affordable Water and Sanitation Technology (CAWST) is encouraging Albertans to play an active role in addressing a global challenge – the lack of access to safe water, sanitation and hygiene worldwide. This comes at a time when the COVID-19 pandemic has heightened awareness around access to safe water and sanitation as a basic human right.
Practicing simple hygiene, especially handwashing, plays a critical role in reducing the transmission of COVID-19, and yet three billion people worldwide lack basic handwashing facilities with soap and water at home.1 CAWST is committed to addressing issues around clean water and sanitation by empowering communities to create long-lasting change. For 20 years, CAWST has provided people with the knowledge and skills they need to implement these proven solutions through local partnerships, training workshops, online resources and access to simple, affordable technologies.
"COVID-19 has had devastating impacts around the world and has brought other global challenges to the forefront, including access to water," said Shauna Curry, CEO CAWST. "Much like COVID-19, the need for water, sanitation and hygiene is a global crisis that demands world-wide attention and effort to solve it. We're calling on Albertans to join the cause—whether it's by educating themselves, fundraising or donating—to help ensure people have the opportunity to succeed because their basic water and sanitation needs are met."
Partnerships with both international and in-country organizations are key to reaching everyone with clean water and sanitation. CAWST is a leading collaborator in global efforts to achieve safe water, sanitation and hygiene, including its role as a founding partner of COVID-19 Hygiene Hub. With the support of organizations like the World Health Organization and UNICEF, Hygiene Hub provides free technical support, resources and advice to help develop and execute hygiene strategies in low- and middle-income countries.
A United Nations-observance held every year, World Water Day celebrates water and strives to raise awareness of the 2.2 billion people living without access to safe water worldwide.2 This World Water Day, CAWST is calling on Albertans to support this important cause. For more information and to learn how you can help, visit CAWST.org/WorldWaterDay.
The Centre for Affordable Water & Sanitation Technology (CAWST) is a Canadian charity and licensed not-for-profit professional engineering consultancy. CAWST teaches people how to access safe drinking water, sanitation and hygiene in their homes, schools and clinics, using simple, affordable technologies. To do so, CAWST transfers knowledge and skills to organizations and individuals in low- and middle-income countries offering workshops, open content training resources and consulting services. To learn more about CAWST and its work towards making water, sanitation and hygiene a reality for all, visit cawst.org.
SOURCE CAWST
Clinical Study Shows Karallief® Easy Climb™ Significantly Improves Joint Comfort in 30 Days
Results confirm herbal formula made with scientifically tested ingredients offers a highly effective and safe joint support option
Participants saw a 71% decrease in discomfort scores
CAMBRIDGE, Mass., March 15, 2021 /PRNewswire/ -- Karallief®, Inc., a nutraceutical company that researches, creates and distributes clinically studied combination herbal extract formulas, today announced the results of a new clinical study that found its latest formula, Karallief® Easy Climb™, could be a fast-acting natural solution for joint discomfort. Published in the International Journal of Basic & Clinical Pharmacology, the study found that Karallief® Easy Climb™ improves joint health and mobility in as little as 30 days.
The clinical study shows that Karallief® Easy Climb™ could be a fast-acting natural solution for joint discomfort
"Many supplement manufacturers, distributors and consumers are often skeptical about the effectiveness of herbal ingredients for joint support given the lack of clinically backed findings," said Krishna Rajendran, CEO of Karallief®, Inc. "After extensive research and testing of different ingredients for joint health, our team of scientists discovered the synergy that exists when certain standardized herbal extract ingredients are combined in specific ratios. They subsequently developed a unique and effective multi-ingredient formula based on this synergy for supporting healthy joints, including cartilage, tendons and bones."
Karallief® Easy Climb™ was tested over the course of 120 days in a randomized, double-blind, placebo-controlled clinical study on participants experiencing age-related knee concerns. One group of 40 participants received 1,000 mg of the Easy Climb™ formula each day, and a second group of 40 subjects served as the control and received a placebo. During the trial, the participants taking Easy ClimbTM experienced a:
71% decrease in discomfort scores compared to a 49% score for the placebo group
25% increase in joint space width, double that of 11% for the placebo group
8% improvement in the range of knee flexion, double that of the placebo group value of 4%
16% increase in the number of sit-stand repetitions versus the placebo group value of 8%
Karallief® Easy Climb™ is a patent-pending herbal formula that is available in powdered form to provide potency and long-term shelf life. This delivery method lends the most flexibility to formulators, making it easy to add to vitamins, supplements, protein powders, beverages and more. Karallief® Easy Climb™ is vegan, Non-GMO Project verified, and made with a potent 1,000 mg per day blend of standardized herbal ingredients known for supporting healthy joints including Cardiospermum Halicacabum (Balloon Vine Extract), Vitex Negundo (Five-Leaved Chaste Tree), Boswellia Serrata (Frankincense), Bambusa Arundinacea, (Bamboo), Citrus Sinensis (Sweet Orange) and Curcuma Longa (Turmeric).
For more information on Karallief® Easy Climb™, please visit www.easyclimb.com.
The statements in this press release not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. These products are not offered for sale to consumers. These products and information here are only intended for manufacturers for professional product development purposes.
ABOUT KARALLIEF®, INC. Based in the U.S., Karallief®, Inc. researches, develops and distributes combination, custom and single herbal extract formulas to companies around the world in the dietary supplement, skincare and food industries. While many ingredient suppliers use inferior, untested materials that lack quality control measures, Karallief, Inc® offers safe, efficacious and scientifically-backed ingredients that are tested through thorough quality control procedures using high-end testing equipment, and their formulas are manufactured in GMP & ISO 22000 certified facilities. For more information, please visit www.karallief.com.
Glaucoma is a Leading Cause of Preventable Blindness: Don’t Skip Eyecare Checkups
New York, NY, March 15, 2021 — Blindness caused by glaucoma is insidious. In most cases, there is no pain, and the loss of vision occurs slowly from peripheral to central. Many people do not even realize it’s happening until they have lost a substantial amount of peripheral vision. But Dr. Daniel Laroche, Director of Glaucoma Services and President of Advanced Eyecare of New York, wants you to know there is a way to prevent the devastating effects of glaucoma: Don’t skip your eyecare visits.
What is Glaucoma? Glaucoma is a disease of the eye characterized by three components:
1. Damage and loss of the retinal ganglions cells and optic nerve described as cupping
2. Loss of visual field
3. Usually increased eye pressure (the mean normal eye pressure is 15mmHG)
People at risk for glaucoma include the elderly, Blacks, people with elevated eye pressure, primary relatives with glaucoma, persons with high myopia, high hyperopia, history of eye trauma and diabetes.
The elevated intraocular pressure from glaucoma damages the optic nerve mechanically and creates decreased blood flow to the eye. The most identifiable cause of glaucoma is the enlarged lens or cataract in the eye. Early cataract surgery and trabecular bypass has become the best option to stop vision loss in patients with glaucoma. The current use of eyedrops and laser help to lower intraocular pressure but do not address the causative mechanism of the glaucoma being the enlarged lens. Incisional cataract surgery and glaucoma surgery is often needed to truly stabilize glaucoma.
All people should be screened regularly for glaucoma as part of a medical eye exam. Screening should consist of an eye examination consisting of gonioscopy (examination of the drainage angle), intraocular pressure measurement with Goldmann applanation tonometry and a dilated optic nerve examination. If there appears to be any damage to the optic nerve or abnormal pressure, then a visual field test should be performed, and optic nerve photos taken. Persons with thin corneas should be more aggressively monitored and treated for glaucoma as the disease tends to be worse in these patients.
If you have eye pressure or glaucoma and feel that you may be losing vision, Dr. Laroche recommends that you seek the care of a glaucoma specialist for a second opinion. DON’T GO BLIND FROM GLAUCOMA! People with conditions such as glaucoma and diabetic retinopathy that could lead to blindness if left unchecked need to stay particularly vigilant with their checkups. The pandemic shouldn’t keep you from visiting your doctor, but for patients over 60, Dr. Laroche advises it's better to stay home and do telehealth visits or video consultations until the pandemic flattens. He also encourages people to wear face masks on visits and maintain social distancing, even if they are in a health clinic, and if you’re high-risk, consider adding eye protection when in public spaces.
“Eyesight or human vision is one of the most important senses. As much as 80 percent of what we feel comes through our sense of sight. By protecting the eyes, people will reduce the chance of blindness and vision loss while also staying on top of any developing eye diseases, such as glaucoma and cataracts.
“A healthy brain function requires a healthy vision. The brain is our most essential organ, and it allows us to control other organs. Normal and healthy vision contributes to improved learning and comprehension for a better quality of life,” says Dr. Laroche.
About Dr. Daniel Laroche
Dr. Laroche is an exceptional glaucoma specialist in New York. He studied and received his bachelor's degree from New York University and a medical doctorate with honors in research from Weil Cornell University Medical College. He underwent a medical internship at Montefiore Hospital and finished his ophthalmology residency at Howard University Hospital in Washington D.C., where he was the chief resident in his third year. He later completed his glaucoma fellowship at New York Eye and Ear.
