Leading distiller of organic spirits offers freeze-and-eat adult treats free from chemicals and artificial colors
Minneapolis, MN ( May 21,2020 ) – Drake’s Organic Spirits announced today that its popular Spiked Iceä freeze-and-eat adult pops are now available at all 205 Save Mart Companies locations throughout Northern/Central California.
“We’re beyond thrilled to offer Drake’s Organic Spiked Iceä to Save Mart customers,” said Drake’s Founder and CEO Mark Anderson. “Our products are a perfect fit for The Save Mart Companies ‘fresh comes first’ philosophy. Consumers want cleaner options for their bodies and they want products that are friendlier to the planet. Drake’s accomplishes both.”
Based in the heart of the Central Valley, The Save Mart Companies operates 205 traditional and price impact stores under the banners of Save Mart, Lucky, Lucky California, FoodMaxx, S-Mart Foods, and Maxx Value Foods.
Drake’s Organic Spiked Iceä are handheld ice pops that feature 15% ABV and only 80 calories each. Spiked Iceä comes in four flavors - Mango Rum Punch, Vodka Lemonade, Watermelon Martini and Classic Mojito - and are made with Drake’s award-winning all-organic ultra-premium vodka and white rum. They contain no artificial colors or flavors and freeze with twice the ABV as other brands.
Drake’s Organic Spirits is the first and only spirit line in the world to be certified USDA organic, non-GMO Project Verified, gluten-free, vegan and kosher. The five certifications ensure a cleaner drinking option that comes only from the highest quality organic ingredients. Drake’s continues to be among the most environmentally conscious brands in the spirits industry and deeply committed to using ingredients and processes that lead to a more sustainable planet.
In 2019, Drake’s Organic Premium Vodka was awarded Double Gold and Drake’s Organic White Rum received Gold at the Wine & Spirits Wholesalers of America (WSWA) Convention & Exposition in Orlando, FL. The highly-respected awards are widely considered among the most prestigious in the industry because judges are industry experts who blind taste-test each spirit.
Proceeds from the sale of all Drake’s Organic Spirits products help fund Long Lake Animal Rescue, an animal rescue foundation that takes in animals in urgent need of a second chance at life.
About Drake’s Organic Spirits Minneapolis-based Drake’s Organic Spirits was launched in 2017. Drake’s uses the highest quality USDA organic and non-GMO Project Verified ingredients to create a line of ultra- premium spirits and mixes. Drake’s Organic Vodka, Drake’s Organic White Rum and Drakes Organic Spiced Rum offer a no-grain, no-gluten, no-gmo, ultra-premium and 12-times distilled handcrafted spirits at a better price than the leading premium brands. The company recently began producing bulk sanitizer to meet the need for cleaner, safer environments.
About The Save Mart Companies The Save Mart Companies operates 205 stores throughout California and Northern Nevada under the banners of FoodMaxx, Lucky and Save Mart. The Save Mart Companies is committed to sourcing a wide variety of local products to communities throughout California and Northern Nevada. In addition to its retail operation, the company also operates Smart Refrigerated Transport and is a partner in Super Store Industries (SSI), which owns and operates a distribution center in Lathrop and the Sunnyside Farms dairy processing plant in Turlock. For more information on the company, please visit: www.TheSaveMartCompanies.com.
Beli Announces New Product Line to Fill A Major Void In The $23B Fertility Market
Beli’s proprietary, science-backed Vitality blend is the first of its kind focused on men and includes all-natural Shilajit as a key ingredient; draws seed round investors and early customer traction
Seattle, WA – May 19, 2020 -- Beli, Inc., science-backed prenatal products helping couples conceive healthy pregnancies, today announced the launch of its first line of clean, science-backed modern prenatal vitamins for men that fills a huge void in the $23 billion fertility market. The company announced a campaign called #spermcounts bringing awareness to the importance of optimizing sperm health to increase a couple’s chances for a healthy pregnancy.
Beli VitalitySM, a male prenatal, was specially formulated to help the 100+ million people trying to get pregnant each year increase their chances of conceiving and sustaining a healthy pregnancy. Research and market data trends from the National Institute for Health and others prove that fertility issues are on the rise. 1 in 5 couples will seek fertility care over their lifetime. More than 40% of couples who have fertility issues are due to poor sperm quality and quantity on the male side of the equation. According to the Eunice Kennedy Shriver National Institute of Health and Human Development reports that overall, one-third of infertility cases are caused by male reproductive issues, one-third by female reproductive issues, and one-third by both male and female reproductive issues or by unknown factors. In fact, only 1 in 4 men have optimal semen quality. It’s been well established that nutritional deficiencies in the man contribute to risk factors around sperm health, fertility, conception, miscarriage, birth defects, overall health, and the future health of the baby, so the emphasis on nutritional optimization for the male is critical.
“Some factors related to fertility are beyond your control. But you would be surprised how much power you have over the health and vitality of your sperm,” says Edmund Sabanegh, MD, Department Chair of Urology at Cleveland Clinic.
“Fertility and reproductive health is a $23 billion dollar industry and growing at warp speeds but men are often overlooked in the pregnancy equation, despite the fact sperm health is 50% of the equation and plays a dramatic role in not only creating, but also sustaining a successful pregnancy,” said Joni Hanson Davis, CEO and Founder of Beli. “Despite the importance of the male side of the equation, the vast majority of products in the market have been focused on women. It is surprising that in 2020, women still bear the physical and psychological burden of getting and staying pregnant when science is telling us men’s sperm health is just as important as her egg health. One of the easiest ways to increase sperm health is to take a male prenatal that is optimized for his reproductive health. If you are in your reproductive years, we believe men should be taking Beli over a general multi-vitamin.”
Davis continued, “With stories hitting daily about the massive decline in sperm counts, couples having children later in life, pressure to freeze eggs, rise in infertility treatments, and the growth of fertility centers and sperm banks, one of the easiest things we can do and what we must do is get healthy during our reproductive years – and that goes for both him and her. We need to elevate that message because science tells us this is a big part of the equation that is not being addressed.”
That message is resonating with customers who are seeking out Beli to help increase their chances for a successful conception and pregnancy. "Beli was referred to us by my husband’s sister. She had heard from a friend of a friend who had used Beli to get pregnant. She recommended it to us because my husband had some personal concerns about his fertility. We ordered a bottle to see how it would go. He took the pills diligently and within the first month off birth control, we were pregnant.” – Beli customer Hailee. You can read more in her path to pregnancy story.
Beli Vitality for Men
Most men produce millions of new sperm every day and it takes around three months to fully mature. A lot can happen in those three months that can affect the overall health and capabilities of that sperm. The sperm provides 50% of the genetic material for the baby, and if the sperm is not healthy enough to preserve that material or penetrate the egg, that fetus will never occur or probably develop.
Evidence shows that the most common cause of sperm deficiencies are nutrient shortages. Just like women, men’s bodies need different vitamins and minerals to produce healthy sperm. Taking steps to maintain sperm health, even if no fertility issues are present, can dramatically improve how quickly the woman conceives and the viability of that conception.
Beli’s Vitality provides men with the right nutrients optimized for reproductive and sperm health, with some amazing bonus benefits of energy, balance, and overall wellness. Beli’s proprietary Vitality blend is the first to include the all-natural Shilajit as a key ingredient to improve sperm quality and overall fertility potential of men. Clinical investigations have confirmed Shilajit’s effectiveness in improving sperm count and overall sperm quality.
Beli includes high-quality ingredients that have been clinically proven to help:
Improve sperm health
Increase sperm count
Protect sperm while they grow
Improve sperm quality
Increase egg penetration
Balance acid-alkaline balance so sperm survive and work properly
Naturally boost energy
Improve cellular health
“In our opinion, Beli is one of the best male fertility supplements out there. Beli’s supplement contains a proprietary ingredient blend specifically designated to improve sperm count, sperm growth, sperm quality, and sperm motility. Every single ingredient in Beli is thoughtfully included due to research indicating how that particular ingredient will improve a man’s sperm,” said of Arielle Spiegel, CEO and founder, CoFertility. “Beli is basically the gold standard of male fertility supplements, and they’ve really done their diligence to make sure they’ve included everything you need and none of the junk that you don’t.”
Numerous scientific studies published on the National Institute for Health have proven that nutrients like L-carnitine, Vitamins C and E, N-acetylcysteine, Zinc, and Coenzyme Q10 could increase male fertility four-fold. One study from the International Journal of Reproductive BioMedicine found that a combined supplementation of folate and zinc for a period of 26 weeks increased total sperm count in men with optimal and sub optimal sperm counts. In fact, it increased normal total sperm count by 74 percent. Also interesting in this study, before supplementation was started, seminal folate and zinc levels were not significantly different in the fertile and sub-fertile men. This may indicate that even though low folate was not the cause for lower sperm counts, supplementation still helped.
"Trying to conceive is hard enough for a couple. It is even harder when the man does not know how to support his partner. Beli is a solution that allows the man to actively involve himself in the health and vitality of a pregnancy and share the responsibility of reproductive health. I am so excited to see a product that empowers men to help make the trying to conceive journey as successful as possible," said Jess Milanes, Host of Real Talk: Women’s Health and Fertility.
“Your fertility can be an incredibly empowering aspect of your health; the more work you do to nourish it today, the better off you’ll be down the road,” said Davis. “So, think of Beli as your secret weapon in the pregnancy equation. This one habit of taking a daily vitamin will help you get the critical nutrients needed and improve your odds of successfully making your mini me.”
About Beli
Beli is designed to create a positive foundation of health through one small, yet significant act of a daily vitamin. Beli is modernizing the nutritional science market bringing the latest research, science, data, and innovation to consumers to solve some of the most pressing health needs facing us today, including reproductive, prenatal, and fertility, among others to come. Our bodies are constantly changing and rejuvenating, which is amazing, but what those cells are being created from is what we consume. What we put in our mouths is one of the biggest factors how our bodies work and feel, and perhaps the only thing we can control. Our formulas contain high quality, highly activated, bio-available ingredients at optimized levels to ensure nutrients are readily absorbed by the body and can do their job in the way they are intended. Beli takes pride in researching and producing each product with great care and integrity. All products are vegan friendly, gluten free, GMO free, made in an FDA registered facility in the United States, and follow the Good Manufacturing Process Guidelines (CGMP).
Visit us at www.belibaby.com to learn more about the science behind Beli and follow us on Instagram, Facebook, and Medium.
Sheridan Athletics aims to boost student wellness during the pandemic
For immediate release: May 19, 2020
Social distancing. Learning and working remotely. Limiting trips to the grocery store by ordering in. Whatever you’re doing to flatten the curve of COVID-19, you don’t have to do it all sitting down.
That’s the message that Sheridan’s Athletics and Recreation department is sharing with students, through a new initiative - 20-4-20 - that promotes fitness, healthy eating, and general wellness during the pandemic. The 10-week program includes 20 acts of outreach and supports both Sheridan’s student body and the greater community, including five area food banks.
“There’s a million studies on how being active promotes well-being and positivity in general, and it’s obviously much more challenging to stay active during these times,” says Scott Van Hende, Athletics Facility Coordinator at the Davis Campus. “We believe this campaign can help students, who tend to be very social beings and may be finding this pandemic more challenging than others.”
The program launched at the end of April with a donation drive to support five food banks in Halton and Peel. Over the 10-week campaign period, Sheridan’s Athletics department is streaming live or recorded exercise sessions on Tuesdays, and hosting informative or social events on Thursdays. Activities include boot camps, yoga classes, and stretching/mobility classes (via Facebook and Instagram), ESport tournaments, the launch of a Sheridan Run Club with an eight-week challenge, and information sessions about the Ontario College Athletics Association, which oversees college varsity sports in the province.
“It’s a full team effort,” says Van Hende. “Our department was already doing some of these things, and we just switched to a different delivery method – but we’ve also added some new initiatives to promote healthy living during the pandemic.”
As Sheridan campuses remain closed for the foreseeable future, Athletics and Recreation hopes to build on this 10-week initiative to continue outreach and support for students over the summer term.
Lumen Releases First Of-Its-Kind at Home Metabolism Tracking Device, Available Globally Today
Unprecedented Insight into How Efficiently Their Bodies Burn Calories Allows Users to Take Greater Control Over Their Health and Wellness, in the Comfort of Their Home
NEW YORK, May 19, 2020 /PRNewswire/ -- Lumen, a health technology company at the forefront of personal health, today announced the global launch of its ground-breaking wellness device: Lumen. Developed through years of scientific testing and validation, Lumen is the first handheld, portable device and app that measures your metabolism in real-time with just your breath. Lumen is making personal, at home metabolic tracking available outside of research labs for the first time - revolutionizing the way we approach weight loss, fitness and healthy nutrition decision making.
LumenLumen
Lumen works by measuring your body's carbon dioxide concentration by breathing into a handheld Lumen device. These levels, calculated through Lumen's vast scientific research and development, indicate the type of fuel your body is using to produce energy - a mix of fat or carbs. Like having a nutritionist in your pocket, Lumen provides you with personalized suggestions on when and what to eat to fuel your workout, based on your metabolism. Lumen supports fat burn and improves your metabolic flexibility, which is your body's ability to efficiently switch between using carbs and fats as a fuel source.
Research (Calcada et al, Gormsen et al) finds that metabolic flexibility has a profound role in assessing a person's health. People with good metabolic flexibility:
Are in a better position to gain muscle and perform better during workouts;
Find it easier to lose weight and maintain it; and
Are at lower risk of developing obesity, diabetes and metabolic disorders.
Michal and Merav Mor, twin sisters with PhDs in Physiology, co-founded Lumen and act as Head of Science for Product and Head of Research and Science respectively. The sisters conceived of the idea for a personal metabolic tracker as they trained for an Ironman race. Determined to improve their fitness and race times, the scientists sought out a way to track and test their metabolism to achieve peak fitness. Eight years in the making, and on the heels of a successful Indiegogo campaign, they are releasing their groundbreaking device, Lumen, around the world today.
"While metabolism is key to weight loss, the only way to test metabolism was through a restrictive, hours-long laboratory process, leaving regular people with zero visibility into their metabolic rate and only haphazard ways of improving it," said Michal Mor, co-founder and Head of Science for Product, Lumen. "With Lumen, we are bringing scientifically rigorous insight into personal metabolism for the very first time, allowing anyone at home to measure how efficient their body is at burning calories, but also sharing research-driven recommendations on how they can reach their health and fitness goals faster."
The Lumen device and app enable users to maximize their wellness:
Like having a nutritionist in your pocket - Know what and when to eat to fuel your workout, improve your metabolic flexibility and support fat burn.
Track your metabolism daily - See how your metabolism is affected by your sleep, physical activity, and nutrition.
Customize your nutrition - Get daily personalized meal plans. Know exactly what to eat and when.
Workout optimization - See if you have enough energy before a workout or if you need to fuel up. Breathe afterwards to see the impact on your body.
Monitor and improve your metabolic health - Over time, Lumen tracks your metabolism, sleep, nutrition, and fitness data to provide a Lumen Flex Score, which reflects your success and helps sustain results.
At home not a lab - What takes nearly an hour in a lab using expensive and heavy machinery can now be done at home or on the go
Scientific Validation Lumen can provide numerous insights about the metabolism of an individual, as well as valuable scientific data to increase knowledge of metabolic flexibility and nutrition. In a study conducted by San Francisco State University, Lumen has been validated to meet the gold standard for metabolic measurement.
Availability The Lumen device is available at Lumen.me, currently priced at $299 with an MSRP of $349. The device comes equipped with a travel case, charging dock, USB-C Cable, and Premium Customer Support. Users can download the app for free on the Apple App Store and on Google Play.
About Lumen Lumen helps people improve their health and fitness through technology on the forefront of personalized nutrition and metabolism. Conceived and designed by twin sisters, physiology PhDs and Ironman winners, Lumen harnesses the power of our breath to measure metabolism, which is closely linked to weight, fitness and personal health. The Lumen device measures metabolism in a single breath, in less than a minute, which previously was only possible through an hour-long lab test. Available at Lumen.me, Lumen devices ship globally, with the app available on the Apple App Store and Google Play. Lumen is headquartered in Israel, with offices in the United States.
[2] Source: Estradiol acutely inhibits whole body lipid oxidation and attenuates lipolysis in subcutaneous adipose tissue: a randomized, placebo-controlled study in postmenopausal women. Available via:https://eje.bioscientifica.com/view/journals/eje/167/4/543.xml. Last accessed 5 May 2020.
Poor People’s Campaign, National Pan-Hellenic Council hold town hall on COVID-19 impact on African American & poor, low-income communities
The Council of Presidents of the National Pan-Hellenic Council is announcing its full endorsement and support of the Poor People’s Campaign: A National Call for Moral Revival and the call for a digital Mass Poor People’s Assembly and Moral March on Washington on June 20, 2020.
The groups will join forces at 7 p.m. Eastern on Tuesday, May 26, for a town hall titled “Call to Action and Conscience: Racism, Poverty and the Pandemic” to build momentum for the digital assembly and march and to highlight the disproportionate impact of COVID-19 on African Americans and poor and low-income communities.
"The Council of Presidents of the National Pan Hellenic Council recognizes the importance of collectively addressing poverty in America,” Dr. Everett Ward, chair of the NPHC Council of Presidents and president of Alpha Phi Alpha Fraternity Inc., said Tuesday. “As supporters of the Poor People's Campaign, the Council of Presidents will utilize its united voices during the webinar and the June 20th campaign to fight against poverty."
The NPHC, representing nine African American Greek-letter fraternities and sororities and sometimes collectively referred to as the "Divine Nine," is joining forces with the Poor People’s Campaign to build a movement to force the nation to address the interlocking crises of systemic racism, poverty, ecological devastation, the war economy and the distorted moral narrative of religious nationalism.
The partnership was formed after a meeting earlier this month with Bishop William J. Barber II, DMin, co-chair of the campaign, along with Ward, the nine council presidents and their staff. At that meeting, the NPHC agreed to challenge its organizations to sign up at least 20% of their memberships for the digital assembly and march.
“The time is now! NPHC will use their collective power to ensure that underserved and underrepresented communities have a voice that will not be ignored,” said Vanetta Cheeks Reeder, National Pan-Hellenic Council president. “We all joined our various organizations understanding that we are ‘our brother and our sister's keeper.”
The U.S. Census Bureau reports that African Americans make up 13.4% of this country’s population. But a recent study released by Amfar shows that counties with higher black populations account for more than half of all COVID-19 cases and almost 60% of deaths.
And even before the crisis of the pandemic, this nation suffered from the crisis of poverty -- 140 million Americans, or 43%, were poor or low-income. That included 60.4% of black people (26 million),; 64.1% of Latinx people (38 million), 40.8% of Asian people (8 million), 58.9% of Native and indigenous people (2.14 million), and 33.5% of white people (66 million).
“It is crucial that our collegiate body support the efforts of movements such as the Poor People’s Campaign,” said Kasey A. Coleman, chairman of the NPHC National Undergraduate Leadership Council and international second vice president of Alpha Kappa Alpha Sorority Inc. “As a younger generation today, we must leave our world in a better state than we found it, whether that be socially, culturally, economically and more. This begins with uplifting the voices of poverty to encourage moral change in America.”
The council joins over 100 national partners in the Poor People’s Campaign that are building toward the digital assembly and march.
The Poor People’s Campaign “is bringing together a mighty fusion movement to end poverty, end racism and save the planet from climate change and war,” Rev. Dr. Alvin Jackson, national executive director of the assembly march, and Rev. Erica Williams, co-lead and director of student organizing, said in a statement. “We are so proud to stand with our brothers and sisters from the NPHC to uphold its long tradition of social activism and justice work. Now more than ever we need the NPHC to join hands with faith, labor and civil and human rights organizations to stand up to the forces that threaten our democracy and the soul of our nation.”
The presidents and public health professionals will discuss the dire risk that COVID-19 poses to the African American community and demand a more coordinated federal response.
Other speakers will include Nakiya Wakes of Flint, Michigan, who twice miscarried twins because of the poisoned water in Flint, and Rev. Carolyn Foster, a tri-chair of the Alabama state chapter of the Poor People’s Campaign.
On June 20, the Poor People’s Campaign will hold the largest digital and social media gathering of poor and low-income people, moral and religious leaders, advocates, and people of conscience in this nation’s history.
The National Pan-Hellenic Council, Inc. is composed of nine international Greek-letter sororities and fraternities: Alpha Kappa Alpha Sorority Inc., Alpha Phi Alpha Fraternity Inc., Delta Sigma Theta Sorority Inc., Zeta Phi Beta Sorority Inc., Iota Phi Theta Fraternity Inc., Kappa Alpha Psi Fraternity Inc., Sigma Gamma Rho Sorority Inc., Phi Beta Sigma Fraternity Inc. and Omega Psi Phi Fraternity Inc.
The Poor People’s Campaign: A National Call for Moral Revival, is building a generationally transformative digital gathering called the Mass Poor People’s Assembly and Moral March on Washington, on June 20, 2020. At that assembly, we will demand that both major political parties address the interlocking injustices of systemic racism, poverty, ecological devastation, militarism and the distorted moral narrative of religious nationalism by implementing our Moral Agenda
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The National Pan-Hellenic Council was founded on May 10, 1930, at Howard University in Washington, D.C., with five chartering organizations and now has nine organizations. Its purpose is to foster cooperative actions of its members in dealing with matters of mutual concern. The NPHC promotes the well-being of its affiliate fraternities and sororities, facilitates the establishment and development of local councils, and provides leadership training for its constituents.
Expert reaction to high proportion of blood clotting in COVID-19 patients
By Pratima Chowdary, member of The Physiological Society’s COVID-19 Advisory Panel
Earlier this week, the BBC reported that one third of COVID-19 patients developed dangerous blood clots. While current treatments are mainly focusing on anti-viral and potentially anti-inflammatory, these only address the direct effects of the virus. If the virus is a flood, these treatments controlling the flood but not considering damage caused. In addition to the drugs that treat the immune system overdrive or neutralising the virus, there is an urgent need to focus on medications that address this clot formation including the use of blood thinners, and clot busting agents, especially the right dose and the right patient.
For a more in-depth exploration of the story please see below:
Helpful definitions:
Thrombosis: blood clotting
De novo thrombus formation: a clot that forms at the source rather than moving from another location in the body
Embolism: a clot that results from a blockage migrating through the blood vessels
Hypercoagulability: increased tendency of blood to clot
Anticoagulant: blood thinner
D-dimers: protein that is present when blood clot is degraded
CT Pulmonary angiogram: diagnostic test that gives a picture of arteries in the lungs
Is the figure of ‘one third’ of COVID-19 patients developing blood clots a realistic one? Why is it such a high proportion?
Case series have now been reported from multiple countries quoting a figure as high as 40 % in patients in intensive care. Patients on the ward also have higher prevalence even if not of the same magnitude as the patients on intensive care.
This excess thrombosis has been confirmed in autopsy reports where more extensive thrombosis has been noted in the lungs and thrombosis was noted in blood vessels of other organs.
Are the blood clots different from the ones we routinely see in clinical practice?
A view is developing that the pulmonary artery thrombi in these patients probably represent de novo thrombus formation, unlike the typical clots which represent an embolic phenomenon. In other words, the clots of formed by new deposits in blood vessels rather than clots formed in other parts of the body that migrated. This might explain the slow onset of breathlessness. In some patients, a more typical rapid onset breathlessness secondary to rapid occlusion of the pulmonary vascular tree has been seen.
I suspect a combination of both is common across the patient group, with the smaller peripheral thrombi representing de novo thrombus formation. The thrombi in the larger arteries probably are embolic in origin.
What about treatment strategies for the thrombosis?
An assumption has been made that managing the excess cytokines, and immune activation can address thrombosis. This is a misconception as our experience with other thrombotic conditions, including arterial and venous thrombosis shows that addressing the cause does not clear the clot. The clot is cleared through turnover process called fibrinolysis that is intrinsic to the coagulation process. This can also be facilitated by external medications called clot busters (tissue plasminogen activator or streptokinase)
In the context of thrombosis secondary to modest inflammation or secondary hypercoagulability that is inherited or acquired , anticoagulation is the mainstay of treatment. Primarily they can address the consequences in the coagulation system, i.e. prevent progression and recurrence of thrombosis.
There is also considerable debate if all patients should receive therapeutic anticoagulation. On the other hand, there are concerns about the potential risk of bleeding. A randomised trial is underway, although the trial does not require screening despite the high reported prevalence.
A great emphasis has been put on anti-viral and anti-inflammatory strategies, but sadly studies addressing coagulation have struggled to be badged as ‘important’. While anti-viral and potentially anti-inflammatory strategies may the control the ‘flood,’ i.e. viral infection and related cytokine storm, the ‘flood damage’ i.e. fibrin in the alveoli and bloodstream needs to be addressed by alternate mechanisms.
What do scientists think is the mechanism causing the increase in blood clotting in COVID-19 patients?
A consistent finding is elevated d-dimers, typically between 4 to 10-fold increase are seen. Also, increases as high as 100 to 150 fold have been seen in the very sick patients. Elevated d-dimers have been associated with higher mortality and morbidity. The relationship with the severity of lung disease is not clear.
Several explanations have been put forward, and the mechanisms responsible for the excess thrombosis or coagulation abnormalities in COVID-19 are not entirely elucidated.
Three possible mechanisms can be considered.
Coagulation abnormalities may be secondary to the cytokine storm. This appears to be the most prevalent belief, but it is interesting to note that patients do not have a concurrent decrease in fibrinogen or platelets. Typically, the coagulopathy of a cytokine storm tends to be consumptive with low fibrinogen, low platelets, and elevated d-dimers.
The second possibility is that the endothelium is damaged because of adjacency to the alveolar epithelium, and there is a spill-over of the severe inflammation, a bystander effect. This mechanism can explain the excess of pulmonary arterial thrombosis seen in this group of patients. Typically in this situation, there is an increase in fibrinolysis inhibitors in the alveoli with a spill into the circulation.
The third possibility is that there is direct infection of the endothelial cells. There has been a case report demonstrating this possibility. .
What about investigations for pulmonary artery thrombosis?
CT Pulmonary angiogram can demonstrate thrombi in pulmonary vasculature until the sub segmental level. It has been challenging in these patients as they are breathless with resulting motion artefacts, and the presence of lung pathology makes the smaller thrombi more challenging to visualise
If one accepts that the pulmonary thrombi are developing de novo, screening for them will become important as patients are unlikely to present with the more traditional clinical symptoms.
In our institution, a review of data shows that elevated d-dimers can predict the presence of pulmonary artery thrombosis.
At a minimum patient with high d-dimers, about 4 to 6 times the upper limit of normal should have a CTPA and anticoagulation will address the contribution from PAT.
What other treatments are possible for blood clotting?
Typically, we tend to manage blood clots with anticoagulants, but the clots can be lysed with thrombolytic agents. Thrombolysis for pulmonary embolism can be done as systemic therapy by administering the drug through a peripheral vein or catheter-directed..
There have been a few case series of intravenous tissue plasminogen activator with transient improvement in oxygenation. Most of the studies have been conducted in patients hospitalised in intensive care for long periods, and the lack of effect in clinical outcomes may potentially be related to fibrosis. There is also a study of nebulised tissue plasminogen activator to see if this helps improve oxygenation through lysis of fibrin membranes in the alveoli and small vessel thrombosis.
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1. Pratima Chowdary is consultant haematologist at the Royal Free London, UK and co-centre director for the haemophilia centre at Health Services Laboratories. The Physiological Society’s COVID-19 Advisory Panel was set up to respond to questions, comments and data from front line clinicians dealing with patients. To submit questions and read responses, visit: https://www.physoc.org/covid19/questions/
2. The Physiological Society brings together over 4,000 scientists from over 60 countries. The Society promotes physiology with the public and parliament alike. It supports physiologists by organising world-class conferences and offering grants for research and also publishes the latest developments in the field in its three leading scientific journals, The Journal of Physiology, Experimental Physiology and Physiological Reports. www.physoc.org
AusculSciences Introduces Auscul-X to Help Keep Healthcare Providers Safe During Pandemic
Company's remote, disposable stethoscope will allow physicians and nurses to listen to heart and lung sounds at a safe distance.
OTTAWA, May 19, 2020 /CNW/ - AusculSciences™, a pioneer in developing advanced bioacoustic technologies to detect cardiovascular and pulmonary conditions, today announced that it is developing the Auscul-X™ Touchless Stethoscope System which will allow physicians and nurses to listen to heart and lung sounds at a safe distance from patients with diagnosed or suspected infectious diseases such as COVID-19.
Over 10% of those infected with COVID-19 are healthcare professionals. In response, AusculSciences has re-purposed technology from the CAD-det™ System (approved by Health Canada for investigational use) to help protect physicians and nurses during this pandemic. Using a conventional stethoscope to listen to the heart and lungs of patients with known or suspected COVID-19 forces nurses and physicians to be within arm's reach of these patients multiple times each day. This proximity puts them at higher risk of contracting disease and requires them to don a separate set of personal protective equipment (PPE) for each patient, a time-consuming process.
Auscul-X will provide nurses and physicians the ability to listen to and visualize the sounds of a patient's heart, lungs, and other internal organs from a safe distance, thereby reducing their exposure to infectious diseases such as COVID-19. It also reduces patient to patient transmission from possible bacterial contamination known to occur with traditional stethoscopes in patients with suspected infectious diseases.
Auscul-X includes six sensors worn on the patient's torso. Physicians and nurses can listen to heart and lung sounds either through earbuds connected to the in-room control module, or wirelessly from outside the room on their smartphone, tablet, or workstation computer. Auscul-X is expected to optimize the workflow of healthcare providers by reducing the number of times they change in and out of PPE.
"This is an important advancement with the COVID-19 crisis and represents a major advance in improving the safety and cost efficiency of direct patient assessment," said Cardiologist Dr. George Vetrovec, Chairman Emeritus, Pauley Heart Center, Virginia Commonwealth University. "Auscul-X is a needed and important addition to infective patient management but is far from a single event item - there are extensive opportunities for this technology to balance cost with reduced protective gear use, leading to potentially better outcomes."
AusculSciences plans for Auscul-X to be on-market during the third quarter of this year. Auscul-X will be evaluated on critical care patients in an investigator-led study at the University of Ottawa Heart Institute planned to begin early June.
About AusculSciences
AusculSciences is a medical device, services, and software solutions company dedicated to the development of bioacoustic technologies to detect cardiovascular and pulmonary conditions. AusculSciences' innovative approach provides physicians and nurses with actionable data to support clinical decision making, reduce the cost of diagnoses while improving patient care and provider safety.
SOURCE AusculSciences, Inc.
Moments of Mindfulness for Relieving Stress
“There are many different ways you can do a focused practice of mindfulness through activities like yoga and meditation,” Dr. Brad says. “These types of exercises can take mindfulness to another level, but just focusing on everyday normal activities can boost your energies as well. Pay attention to every aspect of your day, such as:
Eating: Prepare the food yourself. Think about each ingredient, how it will taste, and how it will nourish you. Pay attention to the colors, smells, and textures. When you eat, do only that. Do not read. Do not watch television. Do not use a device. Consider each bite and relish the flavors. Put your fork down between bites and take a few moments to reflect on the bounty before you. Being more mindful when you eat should allow you to get much more enjoyment out of the experience.
Walking: It might seem like a mindless activity, but it doesn’t have to be. In addition to appreciating your surroundings, pay close attention to your movement. Feel the flexing of muscles and stretching of tendons and ligaments. Focus on HOW you are walking. Are you limping? Favoring one side over the other? Make a firm, solid connection with the surface below you, which can help ground you both physically and spiritually.
Listening: Readily available distractions in life have caused many to lose the ability to focus. When that happens, it’s hard to be there in the moment for loved ones who need to talk. You may also be missing out on great stories and creating new memories. Focus on what is being said without replying or interrupting. Pause before saying or doing anything.
“Sometimes there are events in our lives that make us reject mindfulness,” Dr. Brad says. “Trauma can become the building blocks of a Heart-Wall — which we believe is a sort of force field of energy your body may build as a means of protecting yourself from negative energies. It is important to identify and release Trapped Emotions so you can become lighter and more mindful. The Emotion Code® and The Body Code™ are two phenomenal tools that may help you remove Trapped Emotions or other imbalances that could help you be more mindful and help lighten your life.”
About Dr. Bradley Nelson: Veteran holistic physician Dr. Bradley Nelson (D.C., ret) is one of the world’s foremost experts on natural methods of achieving wellness. He has trained thousands of certified practitioners worldwide to help people overcome physical and emotional discomfort by releasing their emotional baggage. His best-selling book "The Emotion Code" provides step-by-step instructions for working with the body's energy healing power. A newly revised and expanded edition of "The Emotion Code" is now available from St. Martin's Press. For more information and a free Emotion Code Starter Kit, visit www.emotioncodegift.com.
Sugar Meets its Match in Good Dee’s All-New Signature Blend Sweetener Made with Monkfruit and Allulose- the Perfect 1:1 Complement to Cookies, Cakes, Coffee, and More
With just two simple ingredients, Good Dee’s new Signature Blend Low-Carb Sweetener may just put the real thing in your rearview - for good!
NEW YORK – (May 19th, 2020): Health-conscious baking just got a whole lot sweeter, thanks to Good Dee’s latest May 15th release: a Signature Blend sweetener featuring two simple ingredients and 0 grams net carbs. Founded and led by native Texan-turned-New Yorker Deana Karim, Good Dee’s delivers a wide selection of full-flavored, low-carb baking mixes and pantry staples made with the highest-quality, innovative ingredients and no added sugar. Offering a variety of delicious sweet and savory options compatible with most diets - including gluten, soy, wheat, nut, and dairy-free - the clean-eating company’s latest Signature Blend sweetener is the perfect sugar-free compliment to cookies, cakes, coffee, tea, and more.
An easy 1:1 sugar replacement, Good Dee’s Signature Blend Low-Carb Sweetener is sugar alcohol-free and vegan, featuring a delectable and extremely low-calorie combination of allulose and monkfruit. Found naturally in dried fruit, low-glycemic allulose offers a similar appearance and texture to sugar without the high calories and no glycemic impact. Monkfruit offers anti-inflammatory benefits with all the sweetness of sugar, free of calories, net carbs, and the unwanted side effects that can arise from artificial sweeteners (such as allergic reactions and bloating). “Allulose is a fantastic and healthier sugar alternative,” explains Karim, “but only 70% as sweet as sugar - so adding the monkfruit really helps!”
Try the all-new Signature Blend Low-Carb Sweetener in any recipe that calls for sugar or in Good Dee’s fiber and antioxidant-rich Chia Strawberry Jam recipe:
1 Cup Frozen Strawberries
4 Tbs Chia Seeds
3 Tsp Good Dee’s Signature Blend Low-Carb Sweetener
In a bowl, mash fruit with a fork (or blend for ease). Add chia seeds and sweetener to fruit liquid and let sit for 10-15 minutes. Mix thoroughly and enjoy in thumbprint cookies or almond butter and jam sandwich.
Featuring nothing but real, honest ingredients, discover the full collection of delectable, allergen-free Good Dee’s all-in-one baking mixes (just $11.99 each) and pantry staples at select natural food stores, supermarket chains, and independent grocery stores nationwide. Explore new Blueberry Pancake and Chocolate Brownie Low-Carb Baking Mixes, along with mouthwatering extras - like sugar and dairy-free Sprinkles and Food Sparkle, and sugar-free Maple Syrup (sweetened with allulose) - at GoodDees.com. Get inspired by innovative clean eating recipes and baking ideas to satisfy every craving on Instagram @GoodDeesMix.
About Good Dee’s:
Created and founded by native Texan-turned-New Yorker Deana Karim, Good Dee’s proves that health-conscious living and decadent indulgence really do mix. Give in to cravings guilt-free with Good Dee’s complete collection of baking mixes designed for low-carb, restricted, and special diets. The tasty solution to a lifetime of deprivation and struggle with weight gain, Good Dee’s offers innovative, full-flavor mixes free of gluten, soy, dairy, wheat, and added sugar. Also available in nut-free brownie, blondies, chocolate snack cake, and muffin mix. Learn more and shop all flavors and varieties - priced at just $11.99 each - online at GoodDees.com. Find inspirational recipes and baking ideas on Instagram @GoodDeesMix.
SteadyMD Collaborates with CareDash to Match Doctors with People Nationwide for Online Care
Now people in all 50 states can access telemedicine with a personal SteadyMD doctor online via video chat, text or phone.
ST. LOUIS, MO and CAMBRIDGE, MA—May 19, 2020—Delivering telemedicine technology and services by matching doctors and patients across the nation, SteadyMD today announced a new partnership with CareDash. The collaboration will further simplify the way people can engage with doctors online to build a long-term health care relationship, via video chat, text or phone. Now with CareDash and SteadyMD, people can find, compare and review personal online doctors at their fingertips.
"Many people in cities and rural or remote locations are asking about telehealth–what it is and how to find the right online doctor," said Lindsey Johnson, SteadyMD director of partnerships. “SteadyMD and CareDash provide options for online doctors from anywhere across the nation—not just those in local zip codes—who best align with the patient’s medical concerns, lifestyle and healthcare values. People are turning to telemedicine from SteadyMD to build a long-term relationship with a doctor who knows them, understands them and supports them to become the best version of themselves over time.”
Telemedicine Visits on Track to Top One Billion Visits by the End of 2020
According to Arielle Trzcinski, a senior analyst at Forrester Research, the adoption and use of telemedicine has greatly increased since March with telemedicine visits on track to top one billion by the end of 2020. That represents a massive expansion from telemedicine usage before the coronavirus pandemic.
“There were three barriers that impacted the lack of adoption, or the slowness of adoption [of telemedicine], before the pandemic hit. We saw cost ... availability ... and then we also saw relationships playing a factor,” said Arielle Trzcinski, as quoted in CNBC’s article, “Telehealth visits are booming as doctors and patients embrace distancing amid the coronavirus crisis.”
Adoption has soared for SteadyMD amid the pandemic. The company is on a mission to make high-quality, high attention concierge-like healthcare available and affordable to millions of Americans with board-certified doctors. Consumers can now rely on CareDash’s information, ratings and reviews to research providers in order to select physicians, including telehealth care providers from SteadyMD. CareDash allows direct access to patient experience information, including a breakdown of the 10 key areas patients care most about, such as the thoroughness of the provider's exam, their ability to answer questions, the clarity of instructions, and the provider's attitude and bedside manner, to name a few.
"Patients are looking for trust and transparency when it comes to their healthcare, especially as they evaluate the rapidly expanding set of telemedicine options available to them," said Niklas Kubasek, senior vice president of partnerships at CareDash. "SteadyMD offers a unique approach to providing a virtual primary care experience where patients can build an ongoing and lasting relationship with their physician. We're excited to make this another reason why millions of patients are using CareDash each month to find the right healthcare provider."
SteadyMD Media Contact: Heidi Wieland, heidi@steadymd.com, (805) 722-7413
About SteadyMD
On a mission to provide personal online doctors to people everywhere, SteadyMD is a technology company and telehealth provider. Board-certified doctors practice Primary Care, Functional Medicine and Pediatrics in all 50 U.S. States.
SteadyMD partners with leaders in healthcare across industry and with government agencies to connect people to high-quality telehealth from the convenience and safety of their homes or from any location via video chat, text or phone.
For more information about partnerships, contact Lindsey Johnson: lindsey@steadymd.com.
Founded by Guy Friedman, CEO, and Yarone Goren, COO, SteadyMD is headquartered in St. Louis, MO with a satellite campus in Los Angeles. For more information or to become a SteadyMD member, please visit https://www.steadymd.com.
About CareDash
Headquartered in Cambridge, Massachusetts, CareDash is a healthcare search engine used by more than 2 million patients every month in the U.S. CareDash is committed to making it easy to find accessible information that helps patients make the right decision about their provider of care, including doctors, dentists, therapists, and hospitals.
CareDash works with hospitals, specialty groups, telemedicine platforms, and healthcare agencies to drive new patient engagement. For information about partnerships, contact Niklas Kubasek.
For more information on CareDash, visit https://www.caredash.com or follow on Twitter @CareDash.
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