STAY ALERT COFFEE LOVERS, SOMETHING BIG IS BREWING WITHIN SINGLE-SERVE COFFEE

WEST COAST STARTUP SOLVES THE SINGLE-SERVE COFFEE CRISIS 

TO DELIVER QUALITY WITHOUT COMPROMISE 

The Award-Winning Steeped Coffee full immersion brew method means no machines, no waste, guilt-free packaging, and amazing taste

[Santa Cruz, CA, JULY 9, 2019] – Step aside, coffee pods. Take a rest, instant coffee. There’s finally a single-serve option available in the world of high-end coffee, and it’s quickly becoming a game changer. 

Santa Cruz-based startup Steeped, Inc., one of the most promising and innovative companies in the industry, has launched its revolutionary Steeped Coffee brewing method to serious coffee drinkers across the nation. Brewed similar to tea, Steeped Coffee’s nitro sealed Steeped Bags, along with their guilt-free packaging made using renewable and compostable materials, achieve the unthinkable: freshly ground specialty coffee in a single-serving. That’s why it earned the “Best New Product” award for their innovative packaging at the recent Specialty Coffee Expo. And, it’s barista-approved!

Steeped Coffee launched when serial entrepreneur and coffee lover Josh Wilbur decided to combine the convenience of a single-serving brew method with the premium quality of ethically sourced coffee. Wilbur wanted to redeem the environmental dilemma created by wasteful coffee pods. Happy to do the math, Wilbur points out over 10 billion unrecyclable pods accumulate in landfills each year – enough to wrap around the earth more than 110 times if placed side-by-side. Moreover, each type of pod depends on expensive and often moldy brewing machines, which are also unrecyclable. 

It took Wilbur seven years to innovate the proprietary Steeped Coffee system that delivers fresh roasted, pre-portioned, precision ground, micro batched coffee in customized Full Immersion Filters. “Premium coffee roasters have shied away from offering their specialty beans in single-serve packaging because it’s been nearly impossible to keep ground coffee fresh, which quickly ruins the taste,” said Wilbur. “With our Nitro Sealed bags, oxygen is replaced with nitrogen, so the coffee stays fresh as if it was ground moments ago.”

“Steeped Packs are the easiest way to make a delicious cup of coffee,” Wilbur Says. “You shouldn't need to perform chemistry before you’ve made your coffee.” Simply steep each Steeped Bag in hot water for about five minutes to allow the coffee to develop its distinctive body and flavor. There is no machine, no noise, no cleanup, no destructive waste.

As for flavor? Even the most discerning coffee connoisseurs in the industry are singing the praises of Steeped Coffee. Barista Magazine is a believer: “Like a tea bag—but for coffee? This new product from Steeped Coffee might just be one of our fave new ways to brew coffee on the road.”

“Finding Steeped has changed my coffee drinking life,” raved one reviewer on Producthunt.com. “It's my favorite new brewing method and I can't believe more people haven't heard of this yet. It is going to be huge.”

Entrepreneur’s Handbook concurs: “You’re likely going to see the Steeped Coffee methodology in hospitals, offices, hotels — places where single-serve coffee reigns — and perhaps on your next flight.

Features of Steeped Coffee include:

  • 100% Specialty Coffee: quality coffee ethically sourced directly from farmers
  • Nitro Sealed: removes oxygen, stopping the clock on freshly ground beans
  • Ultrasonic Edges: no glue, staples, or wasted materials for max steeping
  • Full Immersion Filter: non-GMO filters that regulate ideal water-in and maximum flavor-out
  • Guilt-Free Packaging: made using plant-based renewable and compostable materials
  • Micro Batching: roasted locally in small batches
  • Precision Ground: consistent water-cooled grinding to the micron
  • Pre-Portioned: consistent SCA recommended water-to-coffee ratios
  • Just Add Water: single-serve convenience with no machines required
  • Barista Approved: tested by multiple independent specialty coffee Q-graders for freshness, quality, and taste
     

About Steeped Coffee

Steeped, Inc., based in Santa Cruz, California, is a B-Corp (Benefit Corporation) focused on every detail from farm-to-cup and beyond, to bring people the most convenient, quality, ethically sourced, and sustainably packaged products available. Steeped Coffee provides a single-serve method that combines convenience and quality all within Guilt-Free Packaging. The proprietary Steeped Brewing Method delivers 100% freshly roasted, precision ground, and nitro sealed specialty coffee pre-portioned within Steeped Full Immersion Filters. Steeped Coffee is the simplest way to make a perfect cup of coffee, with no machine needed, just add water. Steeped, Inc. offers its brewing method to Licensed Partners around the globe. For more information, visit http://www.steepedcoffee.com. For business inquiries, contact sales@steepedcoffee.com.

With so many coffee gadgets, machines, and accessories flooding the market these days, this simple unplugged Steeped Coffee brewing method might be just what you're looking for to take your moment, while at home, at work, or on-the-go.
 

https://drive.google.com/drive/folders/17Pd1uZH_JxUCrO-huplKbV-MgdOLOwms

Photo: The Steeped Coffee full immersion brew method means no machines, no waste, guilt-free packaging, and amazing taste.

Steeped_Coffee_Medium_Roast (1).jpg

Many individuals are worried that sexualization in video games may increase female players' body dissatisfaction. 

Contrary to expectations, new research findings in the American Psychological Association's journal Psychology of Popular Media Culture did not find that sexualization increased body dissatisfaction or aggression toward other women. Media influences from video games appear to be minimal.

"Examining the Effects of Exposure to a Sexualized Female Video Game Protagonist on Women's Body Image" is based on research by Danielle Lindner, Ph.D., assistant professor of psychology at Stetson University; Chris Ferguson, Ph.D., professor of psychology at Stetson University; Stetson University alumna Melissa Trible; and Ilana Pilato, Ph.D. candidate, at Fairleigh Dickinson University.

During the study, female players were randomly assigned to play either a more or less sexualized avatar in a "Tomb Raider" video game. Participants also reported on their self-objectification and body dissatisfaction as well as hostility and aggression toward a female character. Research results indicated that exposure to a sexualized avatar in a video game did not influence any outcomes for female participants. These results indicate that, at least for video games, exposure to sexualized females may not have a substantial impact on female players.

The journal article link includes additional information. Dr. Lindner is a body image expert and is available to discuss the research findings that published in the Psychology of Popular Media Culture. Below you will find the journal and faculty profile links.

Psychology of Popular Media Culture journal article link:

https://psycnet.apa.org/doiLanding?doi=10.1037%2Fppm0000251

Dr. Danielle Lindner's faculty profile:

https://www.stetson.edu/other/faculty/danielle-lindner.php

Video game aggression research:

The issue of whether aggressive video games contribute to aggressive behavior in youth remains an issue of significant debate. One issue that has been raised is that some studies may inadvertently inflate effect sizes by use of questionable researcher practices and unstandardized assessments of predictors and outcomes, or lack of proper theory-driven controls. 

New research findings in Springer's Journal of Youth and Adolescence did not find aggressive video games causing future aggression in youth.

"Aggressive Video Games Are Not a Risk Factor for Future Aggression in Youth: A Longitudinal Study" is based on research conducted by Dr. Ferguson and C.K. John Wang, Ph.D., professor of sport and exercise psychology at Nanyang Technological University in Singapore. 

In the recently published journal article, more than 3,000 youth around the age of 11 in Singapore, with nearly 73 percent being male, were assessed for links between aggressive game play and seven aggression or prosocial outcomes two years later. 

Participants were asked to rate three video games they currently played and how often they played them both on weekdays. 

STONEFIELD VILLA RESORT LAUNCHES AN EXCLUSIVE FITNESS RETREAT WITH CANADIAN CELEBRITY AND FITNESS EXPERT JANA WEBB 

TORONTO, ON (July10, 2019) - Stonefield Villa Resort, a premier health and wellness boutique property nestled at the base of Saint Lucia's famous Pitons has partnered with fitness expert and Reebok spokesperson, Jana Webb to launch a weeklong fitness retreat from November 17 – 24th, 2019 offered exclusively through WestJet Vacations.

Webb, an original cast member of the Real Housewives of Toronto, is the founder of JOGA World, a movement system made up of yoga combined with the biomechanics of sports training. Joga was created during a personal journey of rehabilitation following a car crash that left Webb severely injured.  Her unique program enhances athletic performance, improves concentration, decreases recovery time, and ultimately, transforms an athlete's game.

The Jana Webb Fitness Retreat, is an all-inclusive package with roundtrip flights on WestJet, including luxury villa accommodations at Stonefield Villa Resort. The package will feature daily personalized workouts; a 60-minute spa treatment; customized healthy meal options at the resorts award-winning farm to table restaurant - Mango Tree; airport transfers; Sulphur Springs Volcano mud bath excursion, hiking the famous Pitons and a full day catamaran experience along the islands west coast.

Saint Lucia offers travellers an elevated wellness experience; the volcanic island is home to the healing Sulphur Springs, a restorative mineral mud bath, lush rainforests and the iconic Pitons that rise majestically out of the Caribbean Sea. Webb visited Saint Lucia in November 2018 to scout properties for her first fitness retreat aboard. After reviewing the island top wellness attractions and resorts, she selected Stonefield Villa Resort to host her high-end clientele on a week-long fitness/wellness retreat.

“To find a getaway that combines the zen of the ocean and the adventures of the rainforest is rare,” remarked Jana Webb, founder of JOGA. “Stonefield Villa Resort’s exquisite farm to table service and magical views from your own private villa will be a time in your life you will never forget. Saint Lucia will inspire you! My motto in life is work hard and play harder. Join me for the first ever, all-inclusive - Jana Webb Fitness Retreat partnered with WestJet Vacations and Stonefield Villa Resort. I guarantee a week of fun, fitness, amazing food, relaxation, adventure, laughs and friendship.”

The Jana Webb Fitness Retreat is sold exclusively through WestJet Vacations, visit http://westjet.com/stonefield to book you package today or call Toll Free: 1-888-937 - 8538. 

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About Stonefield Resort

Stonefield Villa Resort is one of the most desirable destinations for the discerning Caribbean traveller. This 17-villa boutique property is nestled at the base of St. Lucia's Pitons overlooking the Caribbean Sea. Guests relax, luxuriate and rejuvenate in spacious secluded villas each with large private pools, outdoor garden showers, large verandas and extraordinary views of the Petit Piton and the Caribbean Sea. The resorts' full-service spa, gym, and yoga studio have attracted fitness and wellness groups globally offering annual retreats for exceptional rejuvenation. Consistently rated over four stars on Trip Advisor, Stonefield Resort and Spa has become a yearly award-winning vacation escape for visitors all over the world.

INTRODUCING WONDER MELON™, THE NEWEST IN 

TREND-FORWARD HEALTHY BEVERAGES

KAYCO RIDES THE WATERMELON WAVE WITH HEAVY PROMOTIONAL SUPPORT IN NYC SUMMER 2019

Delicious, Organic Drink Delivers Powerful Hydration in Two Refreshing Varieties:

  • Spicy Watermelon Lemon Cayenne
  • Cool Watermelon Cucumber Basil

Bayonne, NJ, July 9, 2019 – The consumers have spoken. Watermelon, one of today’s fastest-trending fruits, has enjoyed triple-digit growth in casual and fine dining. Demand for the refreshing summer staple is on the rise even in the fall and winter months. It’s a must for any mixologist and you’ll find it on one in 10 restaurant menus.

Most of all, people just love watermelon – and they know it’s good for them.  

KAYCO (www.kayco.com) is taking the beverage industry by storm with Wonder Melon™the latest thirst-quencher for those seeking clean, uniquely flavorful new refreshment options. Wonder Melon™ is made from 100% organic cold-pressed juice with no added sugar, artificial ingredients, or artificial colorings.

This healthy game-changer comes in two exciting varieties. Watermelon Cucumber Basil is a delightfully cool concoction of real watermelon juice, lemon juice, apple juice, cucumber juice, and basil, with only 80 calories per 8.45 oz. bottle. Watermelon Lemon Cayenne wakes up the taste buds with real watermelon juice, lemon juice, apple juice, and a dash of cayenne at just 100 calories per 8.45 oz. bottle.

“Wonder Melon™ perfectly captures what consumers are looking for right now,” says Kim Cassar, Kayco’s EVP Sales & Marketing – Beyond Division.  “It’s not only healthful and out of the ordinary, but also undeniably trendy and irresistibly delicious. We’re confident that Wonder Melon™ will make a huge splash this summer.”

Both varieties are non-GMO verified, certified Fair Trade, USDA organic, and certified OU kosher (parve). Packaged 6 bottles per case ($3.99/bottle MSRP), Wonder Melon™ is available in the refrigerator section at Shop-Rite, Fairway, Best Market, independent grocers and Amazon. 

Promotional Blitz

Kayco is supporting the Wonder Melon™ brand in New York City with an aggressive outreach campaign at the height of cold beverage season. Look for the following promotions:

  • Segments on Time Warner Cable’s A Taste of New York, targeting affluent, influential, and educated New Yorkers. This spot will also be featured on A Taste of New York’s web site, YouTube channel, Facebook page, Twitter feed, Pinterest site and Instagram. Sneak Peak -  https://vimeo.com/tasteofny/download/340913533/0963707776
  • Eye-catching Wonder Melon™ Vans will cruise the steamy summer streets with refreshing samples for thirsty Manhattanites starting July 12 and running all summer. Check Wonder Melon’s™ social media for dates and locations.
  • Giant Wonder Melon™ trucks will roll out the product – literally – to provide additional exposure.
  • In-store support including tastings and point-of-purchase materials.

Watermelon Stats

According to Menu Trends research by the Watermelon Board: 

  • All regions across the U.S. are experiencing increased use of watermelon.
  • Watermelon is featured in one of 10 menus – up by 27% in the last four years.
  • Watermelon is one of the fastest fruit flavors in non-alcoholic beverages, with 29% four-year growth.
  • 82% of consumers surveys said they liked the taste of watermelon.

Wonderful Watermelon Facts

Watermelon’s 92% water content is excellent for hydration. It contains a bounty of nutrients, antioxidants, vitamins, and minerals associated with the following:

  • Digestive health
  • Eye, skin, and hair health
  • Sun protection
  • Diabetes protection
  • Heart and blood vessel health
  • Weight loss
  • Combating asthma
  • Weight loss
  • Nerve function
  • Reduction of inflammation

Wonder Melon™ Recipes:

Cucumber Cooler 

2 oz cucumber mint vodka

1/2 oz lemon juice

.25 oz simple syrup

2 oz Wonder Melon™ with Juice, Watermelon, Cucumber and Basil

Splash cucumber juice

Pineapple Punch

2 oz pineapple infused vodka

1.5 oz Wonder Melon™ with Juice, Watermelon, lemon, and cayenne

Splash simple syrup

.5 oz pineapple juice

.5 oz peach schnapps

Summer Refresher 

2 oz. vodka

1/2 oz. Watermelon juice

1/4 oz. Simple syrup

1 oz. Lemon juice

1 oz. Wonder Melon™ with Juice, Watermelon, Cucumber and Basil

Sugar rim

Wonder Melon Rita

2 oz. Tequila

1 1/2 Wonder Melon™ with Juice, Watermelon, lemon, and cayenne

1 oz. Lime juice

1 Packet of sugar

Top with water, blueberries and mint leaves

 About Kayco Beyond

Kayco is one of the largest manufacturers and suppliers of kosher foods. Its expanded Kayco Beyond Division sources and distributes new products to the general market beyond kosher, to meet the demands of consumers looking for optional products that are healthful, convenient and/or for restricted diets and lifestyles. These brands include Dorot, Absolutely Gluten Free, Beetology, Mighty Sesame, Tuscanini Foods, Wissotzky Tea Co. and new Wonder Melon™. They are headquartered in Bayonne, NJ. (www.KAYCO.com).

Photo:  Wonder Melon™ is the latest thirst-quencher for those seeking clean, uniquely flavorful new refreshment options.  It’s made from 100% organic cold-pressed juice with no added sugar, artificial ingredients, or artificial colorings. Look for the official Wonder Melon™ Mobile Trucks hitting the streets of New York summer 2019.

Wonder Melon-5.jpg

Health Canada Approves Pomalyst®-Based Triplet Combination for Patients With Multiple Myeloma

POMALYST®, in combination with bortezomib and dexamethasone, provides a new medication option for patients living with multiple myeloma

TORONTO, July 10, 2019 /CNW/ - Celgene Inc. announced today that Health Canada has approved a POMALYST® (pomalidomide)-based triplet combination with bortezomib and dexamethasone. This is a new treatment option for patients with multiple myeloma (MM) who have received at least one prior treatment regimen that included REVLIMID® (lenalidomide).

POMALYST® is an oral medication taken daily and is indicated, in combination with bortezomib and dexamethasone, for the treatment of adult patients with MM who have received at least one prior treatment regimen that included lenalidomide.1,2

"The treatment landscape for multiple myeloma has significantly changed over the years. New treatment options like this POMALYST®-based triplet combination allow patients and their physicians to work together to find the best early-line treatment regimen," says Dr. Reece, Princess Margaret Cancer Centre. "In the pivotal clinical trial, OPTIMISMM, we saw the POMALYST®-based triplet combination improve and provide a sustained progression-free survival for multiple myeloma patients who were exposed to, and for the most part refractory to lenalidomide. This is important, as over the last few years lenalidomide has become a standard of care in front-line treatment of multiple myeloma in Canada and until OPTIMISMM, the patient population exposed or refractory to lenalidomide in front line was not well studied. The POMALYST®-based triplet combination is a positive step forward in the treatment journey for multiple myeloma patients and their loved ones."

MM is an increasingly prevalent blood cancer originating from bone marrow plasma cells.3 In Canada, the number of patients living with the disease is on the rise, with eight Canadians diagnosed each day.4

"Multiple myeloma is a complex disease which can impact each patient differently," says Martine Elias, Executive Director, Myeloma Canada. "It is encouraging to see how new treatment options, like the POMALYST®-based triplet combination, successfully treat Canadian myeloma patients."

Health Canada's approval of the POMALYST®-based triplet combination with bortezomib and dexamethasone is based on OPTIMISMM, the first prospective phase 3 trial, including 559 MM patients, to evaluate a POMALYST®-containing triplet regimen in patients.5 Patients participating in this trial were all previously treated with REVLIMID® and the majority, 70 per cent, were REVLIMID® refractory.6,7 All patients had received 1-3 prior antimyeloma regimens and demonstrated disease progression on or after the last therapy.8

Patients who received the POMALYST®-based triplet combination with bortezomib and dexamethasone in the clinical trial had a significantly longer progression-free survival (PFS) of 4.1 months more than those who received only bortezomib and dexamethasone (median PFS 11.2 months versus 7.1 months, respectively).9,10

About Multiple Myeloma

MM is a life-threatening blood cancer characterized by tumor proliferation and suppression of the immune system.11,12 It is a rare but deadly disease – around 2,900 people are diagnosed with MM in Canada and 1,450 Canadians die from the disease each year.13 The typical MM disease course includes periods of symptomatic myeloma followed by periods of remission, and eventually, the disease becomes refractory (non-responsive).14 While all MM patients may experience different symptoms during and after treatment, patients may also experience physical issues.15 These may include bone complications, anemia, infections, kidney damage, high blood calcium and other blood complications, osteonecrosis of the jaw, side effects of medication, as well as bone pain, nerve pain and neuropathy.16MM patients may also experience emotional health issues, with 40 per cent of cancer patients experiencing depression or anxiety.17

About OPTIMISMM

OPTIMISMM is the first phase 3 trial designed to compare the safety and efficacy of a POMALYST®-based triplet combination with bortezomib and dexamethasone versus only bortezomib and dexamethasone as an early line of therapy in patients with relapsed or refractory multiple myeloma (with 1-3 prior regimens of therapy) and prior REVLIMID® exposure, including REVLIMID®-refractory patients.

This multi-center, international, open-label, randomized phase 3 clinical trial included 559 patients (281 patients in the POMALYST®-based triplet combination with bortezomib and dexamethasone arm and 278 in the bortezomib and dexamethasone arm). Demographic, baseline, and prior disease characteristics were generally well balanced between the two treatment arms. All patients had prior treatment with REVLIMID®, with the majority being REVLIMID® refractory (71 per cent in the POMALYST®-based triplet combination arm versus 69 per cent in the bortezomib and dexamethasone arm) and 70 per cent versus 66 per cent, respectively, were refractory to their last treatment. Median follow-up was 16 months.

Results from OPTIMISMM showed that patients receiving the POMALYST®-based triplet combination with bortezomib and dexamethasone treatment achieved a significantly longer PFS than those in the bortezomib and dexamethasone treatment arm (11.20 months versus 7.10 months, respectively [HR 0.61, p= < 0.0001; 95 per cent CI: (0.49-0.77)]), reducing the risk of disease progression by 39 per cent in the POMALYST®-based triplet combination arm. In an exploratory sub-group analysis of patients with one prior line of therapy, median progression-free survival with the POMALYST®-based triplet combination with bortezomib and dexamethasone was 20.73 months versus 11.63 months with bortezomib and dexamethasone (HR 0.54; 95 per cent CI: 0.36, 0.82).

Patients were stratified based on age (< 75 years old versus 75 years old), number of prior anti-myeloma regiments (1 vs. > 1) and β2-microglobulin levels (<3.5 mg/L versus > 3.5 to < 5.5 mg/L versus > 5.5 mg/L). Patients were randomized 1:1 to receive the POMALYST®-based triplet combination with bortezomib and dexamethasone or bortezomib and dexamethasone. In 21-day cycles, patients received POMALYST® 4 mg on days 1-14 (POMALYST®-based triplet combination arm only); bortezomib 1.3 mg/m2 on days 1, 4, 8 and 11 for cycles 1-8 and on days 1 and 8 for cycles 9 and onwards; and dexamethasone 20 mg/day (10 mg if aged > 75 years) on the days of and after receiving bortezomib treatment.

About Celgene's Immunomodulatory Drugs

IMiD® agents are Celgene's proprietary small molecule, orally available compounds for the treatment of some blood cancers. IMiD® agents are hypothesized to have multiple mechanisms of action. They have been found to enhance T cells and (NK) cell-mediated immunity. In addition to immunomodulatory properties, IMiD® agents are hypothesized to have tumoricidal and antiangiogenic activity. Celgene's portfolio of IMiD® agents have become a foundation of multiple myeloma research, with a growing number of studies exploring these compounds as combination partners across a range of settings of the disease.

About POMALYST® (pomalidomide)

POMALYST® in combination with bortezomib and dexamethasone is indicated in the treatment of adult patients with MM who have received at least one prior treatment regimen that included lenalidomide. It belongs to a group of drugs called immunomodulatory drugs (IMiDs®).

About Celgene

Celgene is an integrated global biopharmaceutical company engaged primarily in the discovery, development and commercialization of novel therapies for the treatment of cancer and inflammatory diseases through gene and protein regulation. For more information, please visit the company's website at www.celgene.ca.  

Indications and Clinical Use:

POMALYST® in combination with dexamethasone and bortezomib is indicated in the treatment of adult patients with MM who have received at least one prior treatment regimen that included lenalidomide. 

POMALYST® in combination with dexamethasone is indicated for patients with multiple myeloma for whom both bortezomib and lenalidomide have failed and who have received at least two prior treatment regimens and have demonstrated disease progression on the last regimen. 

Geriatrics (> 65 years of age):

Concomitant administration of dexamethasone may increase the risk of infection, particularly pneumonia; dexamethasone dosing may need to be reduced or interrupted in case of infection. Reduce dexamethasone dose by half in patients >75 years of age.

Contraindications:

  • Pregnant women and women at risk of becoming pregnant 
  • Breastfeeding women 
  • Male patients unable to follow or comply with the required contraceptive measures 
  • Hypersensitivity to POMALYST®, thalidomide, lenalidomide or to any ingredient in the formulation or component of the container 

Controlled Distribution Program:

Available only through a controlled distribution program called RevAid®

Serious warnings and precautions:

  • POMALYST® should be administered under the supervision of a qualified physician experienced in the use of cancer chemotherapeutic agents. 
  • Pregnancy: Potential for human birth defects, stillbirths, and spontaneous abortions 
  • Hematologic: Neutropenia and thrombocytopenia 
  • Infections, including fatal cases 
  • Venous thromboembolism: Deep vein thrombosis (DVT) and pulmonary embolism (PE) 
  • Hepatic: Hepatotoxicity, including fatal cases 
  • Hepatitis B virus reactivation, including fatal cases 
  • Severe dermatologic reactions: Stevens-Johnson syndrome, toxic epidermal necrolysis (TEN) and drug reaction with eosinophilia and systemic symptoms (DRESS), including fatal cases 
  • Tumour lysis syndrome, including fatal cases 

Other Relevant Warnings and Precautions:

  • Cardiovascular disorders 
  • Second primary malignancies 
  • Immune reactions: Use in patients with active hepatitis A, B, or C infection; hypersensitivity reactions (angioedema, urticaria) 
  • Interstitial lung disease 
  • Neurologic: Possible impairment of mental and/or physical abilities; peripheral neuropathy 
  • Use in hepatic impairment or renal impairment 
  • Monitoring and Laboratory testing required 
  • Combination treatment with bortezomib; consult bortezomib Product Monograph prior to initiating treatment 

For More Information:

Please consult the Product Monograph at pomalystpm.ca for important information relating to adverse reactions, drug interactions and dosing information. The Product Monograph is also available by calling 1-877-923-5436.

References:
1 POMALYST® Product Monograph. Celgene Inc. Accessed July 2, 2019.
2 POMALYST® Product Monograph. Celgene Inc. Accessed July 2, 2019.
3 Myeloma Canada. What is multiple myeloma? https://www.myelomacanada.ca/en/about-multiple-myeloma/what-is-myeloma. Accessed June 3, 2019.
Myeloma Canada. What is multiple myeloma? https://www.myelomacanada.ca/en/about-multiple-myeloma/what-is-myeloma. Accessed June 3, 2019.
5 POMALYST® Product Monograph. Celgene Inc. Accessed July 2, 2019.
6 POMALYST® Product Monograph. Celgene Inc. Accessed July 2, 2019.
7 POMALYST® Product Monograph. Celgene Inc. Accessed July 2, 2019.
8 POMALYST® Product Monograph. Celgene Inc. Accessed July 2, 2019.
9 POMALYST® Product Monograph. Celgene Inc. Accessed July 2, 2019.
10 POMALYST® Product Monograph. Celgene Inc. Accessed July 2, 2019.
11 Palumbo A, et al. N Engl J Med. 2011;364:1046-1060.
12 Pratt G, et al. Br J Haematol. 2007; 38(5):563-79.
13 Canadian Cancer Society. Statistics. https://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/statistics/?region=qc Accessed June 3, 2019.
14 Hulin C et al. Leuk Res. 2017; 59: 75–84. 2
15 Canadian Cancer Society. Multiple myeloma – Supportive care for multiple myeloma. https://www.cancer.ca/en/cancer-information/cancer-type/multiple-myeloma/supportive-care/?region=on. Accessed June 27, 2019.
16 Myeloma Canada. Multiple Myeloma Patient Handbook. https://www.myelomacanada.ca/pixms/uploads/serve/ckeditor/myeloma_canada_patient_handbook_10_2017-2.pdf. Accessed June 27, 2019.
17 Myeloma Canada. Multiple Myeloma Patient Handbook. https://www.myelomacanada.ca/pixms/uploads/serve/ckeditor/myeloma_canada_patient_handbook_10_2017-2.pdf. Accessed June 27, 2019. 

SOURCE Celgene Inc.

ProMIS Neurosciences to Present Data at 2019 Alzheimer's Association International Conference

Abstracts selected for oral and poster presentation 

TORONTO and CAMBRIDGE, MA, July 10, 2019 /CNW/ - ProMIS Neurosciences, Inc. (TSX: PMN) (OTCQB: ARFXF), a biotechnology company focused on the discovery and development of antibody therapeutics targeting toxic oligomers implicated in the development of neurodegenerative diseases, will give an oral presentation on its lead clinical candidate, PMN310 for Alzheimer's disease, at the annual Alzheimer's Association International Conference® (AAIC), which occurs July 14-18.  A second poster presentation focuses on the behavior of misfolded TDP43 involved in the development of neurological disorders such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.

AAIC® is the largest, most influential international meeting focused on advancing dementia science. The annual conference convenes the world's leading basic science and clinical researchers, next-generation investigators, clinicians and the care research community to share research discoveries supporting new methods of prevention, treatment and diagnosis of Alzheimer's disease.

ProMIS' Chief Development Officer Dr. Johanne Kaplan will deliver the oral presentation, "Selective Targeting of Amyloid-Beta Oligomer Species By PMN310, a Monoclonal Antibody Rationally Designed for Greater Therapeutic Potency in Alzheimer's Disease," on Thursday, July 18, 2019 from 11:45 AM – 12:00 PM in Concourse Hall 151. Dr. Kaplan's slide presentation will be available on the company's website immediately following the presentation. 

ProMIS' Chief Science Officer Dr. Neil Cashman will deliver the poster (#33496), "The Pathological Interactome of Tdp-43 Includes Human Wildtype SOD1" on Wednesday, July 17, 2019 in South Hall GH. 

The conference takes place at the Los Angeles Convention Center. For more information, visit www.alz.org/aaic

About the ProMIS Pipeline
ProMIS Neurosciences' lead candidate, PMN310, is a monoclonal antibody for Alzheimer's disease created with the ProMIS drug discovery and development platform, a novel, proprietary method for discovering and developing antibodies that can uniquely and precisely target toxic forms of otherwise normal proteins. PMN310 selectively targets the toxic oligomeric species of amyloid beta (Aß), a root cause of Alzheimer's disease. Preclinical studies show PMN310 demonstrates a high degree of binding to toxic oligomers without binding to non-toxic forms of amyloid beta protein and greater selectivity versus other Aß-directed antibodies. ProMIS has developed antibody candidates that demonstrate high selectivity for the toxic species of naturally occurring proteins in the brain, including other antibody candidates for Alzheimer's disease that selectively target toxic Tau, antibody candidates for Parkinson's disease that show best-in-class selectivity for toxic forms of alpha-synuclein, and antibody candidates for ALS that target the toxic form of TDP43.

About ProMIS Neurosciences
ProMIS Neurosciences, Inc. is a development stage biotechnology company focused on discovering and developing antibody therapeutics selectively targeting toxic oligomers implicated in the development and progression of neurodegenerative diseases, in particular Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD). The Company's proprietary target discovery platform is based on the use of two complementary thermodynamic, computational discovery engines - ProMIS and Collective Coordinates - to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this unique precision approach, the Company is developing novel antibody therapeutics for AD, ALS and PD. ProMIS is headquartered in Toronto, Ontario, with offices in Cambridge, Massachusetts. ProMIS is listed on the Toronto Stock Exchange under the symbol PMN, and on the OTCQB Venture Market under the symbol ARFXF.

To learn more, visit us at www.promisneurosciences.com, follow us on Twitter and LinkedIn and listen to the podcast, Saving Minds, at iTunes or Spotify.

The TSX has not reviewed and does not accept responsibility for the adequacy or accuracy of this release. This information release contains certain forward-looking information. Such information involves known and unknown risks, uncertainties and other factors that may cause actual results, performance or achievements to be materially different from those implied by statements herein, and therefore these statements should not be read as guarantees of future performance or results. All forward-looking statements are based on the Company's current beliefs as well as assumptions made by and information currently available to it as well as other factors. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this press release. Due to risks and uncertainties, including the risks and uncertainties identified by the Company in its public securities filings, actual events may differ materially from current expectations. The Company disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

SOURCE ProMIS Neurosciences Inc.

Spectrum Therapeutics partners with Canadian Mental Health Association's Not Myself Today® initiative

SMITHS FALLS, ON and TORONTO, July 10, 2019 /CNW/ - Spectrum Therapeutics ("Spectrum"), the medical division of Canopy Growth Corporation (TSX: WEED) (NYSE: CGC) (the "Company" or "Canopy Growth") is pleased to announce a partnership with the Canadian Mental Health Association ("CMHA"). The initiative, a first of its kind for a leading cannabis company and a national mental health organization, will see the CMHA in collaboration with Spectrum Therapeutics develop an educational content module related to cannabis in the workplace as part of CMHA's Not Myself Today workplace mental health program. The module, slated to launch early next year, will feature a host of physical and digital engagement tools aimed to reduce stigma in the workplace on the use of cannabinoid based medicines. In addition, it will encourage greater healthcare practitioner oversight when patients use cannabis to treat a medical condition. The content will also include video resources featuring medical cannabis subject matter experts and fact sheets that provide detailed information and direct readers to further resources.

"The stigma surrounding medical cannabis and mental illness prevents meaningful action and dialogue among those affected. One of the goals of this partnership is to break that stigma by empowering conversations about mental health informed by evidence-based educational resources," said Dr. Mark Ware, Chief Medical Officer, Canopy Growth. "For Spectrum Therapeutics, this partnership presents a powerful opportunity to improve lives by enhancing physical and mental health through access to education that sparks learning along with conversations about medical cannabis in the workplace."

Estimates suggest one in two Canadians have or will have a mental illness by age 40.[1] Fifty-three percent of Canadians consider anxiety and depression to be epidemic in the country[2] and mental illness is a leading cause of disability claims in the workplace in Canada.

Not Myself Today is an evidence-based initiative designed to help employers and employees transform mental health at work. The program is embraced by more than 500 organizations across Canada and the U.S., reaching more than 350,000 employees. By breaking down barriers and making the topic of mental health engaging and accessible to all employees, Not Myself Today improves mental health literacy, reduces stigma, and shifts workplace culture to be more supportive of every employee's mental health and well-being. For the past six years, the initiative has evolved into a highly-regarded program and counts many of Canada's largest and most respected employers across corporate, government and social sectors as its champions. 

"The mental health-care system of the future is not just in clinics or hospitals—it's in settings like the workplace, where we can promote the skills, knowledge and practices that can improve mental health for the broad population instead of limiting our focus to individual patients," said Fardous Hosseiny, interim National CEO, CMHA. "With the support of partners like Spectrum Therapeutics, our Not Myself Today program will educate, reduce stigma, and foster safe and supportive cultures for the one in five Canadians who experience mental illness in a given year—and for the five in five Canadians who have mental health."

The research on cannabis use and mental illness is still in its infancy and CMHA highlights that more studies are needed to understand the relationship between mental health and cannabis use, both in terms of possible benefits and risks. CMHA and Spectrum Therapeutics strongly advise that individuals speak with a health-care practitioner for advice on any mental health treatment including medical cannabis.

Spectrum Therapeutics has identified mental health as an area with high unmet medical needs and is currently engaged in clinical research in partnership with leading academic institutions and research centres to determine the role cannabis can play in addressing mood and anxiety disorders. Today's announcement builds on Spectrum Therapeutics and Canopy Growth's legacy of furthering the public's understanding of cannabis which includes partnerships with the likes of:

  • Parent Action on Drugs and Canadian Students for Sensible Drug Policy to educate parents, adult caregivers and youth on how to make responsible decisions about cannabis. 
  • The Arthritis Society to create evidence-based resources to help people with arthritis learn more about the potential of medical cannabis as a treatment. 
  • The University of British Columbia by way of a $2.5 million donation to conduct controlled trials examining the potential utility of cannabis in addressing the opioid overdose crisis and to establish the Canopy Growth Professorship of Cannabis Science. 
  • Mothers Against Drunk Driving (MADD) and the Canadian Drug Policy Coalition to conduct an extensive research review that formed the basis for MADD Canada's recommendations on responsible cannabis use and sober driving.

Through these partnerships and support for campaigns such as Not Myself Today, Canopy Growth and its medical division, Spectrum Therapeutics is proud to provide education for patients, their families and healthcare providers on medical cannabis and its role in mitigating some of our most common healthcare issues. 

Here's to Future Growth (and promoting mental wellness).

[1] Smetanin et al. (2011). The life and economic impact of major mental illnesses in Canada: 2011-2041. Prepared for the Mental Health Commission of Canada. Toronto: RiskAnalytica.
[2] Survey commissioned by CMHA and conducted by Maru/Matchbox in Sept. 2018: https://markets.businessinsider.com/news/stocks/over-half-of-canadians-consider-anxiety-and-depression-epidemic-1027539125
Not Myself Today® is a registered trademark of the Canadian Mental Health Association.

About Canadian Mental Health Association
Founded in 1918, the Canadian Mental Health Association (CMHA) is the most established, most extensive community mental health organization in Canada. Through a presence in more than 330 communities across every province and one territory, CMHA provides advocacy, programs and resources that help to prevent mental health problems and illnesses, support recovery and resilience, and enable all Canadians to flourish and thrive. For more information, visit cmha.ca

About Canopy Growth Corporation
Canopy Growth (TSX:WEED, NYSE:CGC) is a world-leading diversified cannabis, hemp and cannabis device company, offering distinct brands and curated cannabis varieties in dried, oil and Softgel capsule forms, as well as medical devices through Canopy Growth's subsidiary, Storz & Bickel GMbH & Co. KG. From product and process innovation to market execution, Canopy Growth is driven by a passion for leadership and a commitment to building a world-class cannabis company one product, site and country at a time. Canopy Growth has operations in over a dozen countries across five continents.

Canopy Growth's medical division, Spectrum Therapeutics is proudly dedicated to educating healthcare practitioners, conducting robust clinical research, and furthering the public's understanding of cannabis, and has devoted millions of dollars toward cutting edge, commercializable research and IP development. Spectrum Therapeutics sells a range of full-spectrum products using its colour-coded classification Spectrum system as well as single cannabinoid Dronabinol under the brand Bionorica Ethics.

Canopy Growth operates retail stores across Canada under its award-winning Tweed and Tokyo Smoke banners. Tweed is a globally recognized cannabis brand which has built a large and loyal following by focusing on quality products and meaningful customer relationships.

From our historic public listing on the Toronto Stock Exchange and New York Stock Exchange to our continued international expansion, pride in advancing shareholder value through leadership is engrained in all we do at Canopy Growth. Canopy Growth has established partnerships with leading sector names including cannabis icons Snoop Dogg and Seth Rogen, breeding legends DNA Genetics and Green House Seeds, and Fortune 500 alcohol leader Constellation Brands, to name but a few. Canopy Growth owns 12 licensed cannabis production sites with millions of square feet of production capacity, including more than one million square feet of GMP certified production space. For more information visit www.canopygrowth.com

About Spectrum Therapeutics
Spectrum Therapeutics, the medical division of Canopy Growth Corporation (TSX: WEED, NYSE: CGC), is dedicated to educating healthcare practitioners, furthering the public's understanding of medical cannabis and its various applications, and cutting edge, commercializable research and IP development. Founded in Canada, Spectrum Therapeutics operates in Australia, South America, Africa and across Europe. Its products are available in a wide range of potencies and formats designed to simplify the dialogue around strength and dosage by applying a colour-coded spectrum to categorize medical cannabis according to THC and CBD levels. 

Spectrum Therapeutics' offerings include whole flower cannabis, oils and new innovations such as Softgels in addition to single cannabinoid medicine Dronabinol under the brand Bionorica Ethics. Through product simplification, robust clinical research and ongoing education of healthcare professionals, Spectrum Therapeutics is committed to addressing the unmet medical needs of patients around the globe.

Notice Regarding Forward Looking Statements
This news release contains "forward-looking statements" within the meaning of the United States Private Securities Litigation Reform Act of 1995 and "forward-looking information" within the meaning of applicable Canadian securities legislation. Often, but not always, forward-looking statements and information can be identified by the use of words such as "plans", "expects" or "does not expect", "is expected", "estimates", "intends", "anticipates" or "does not anticipate", or "believes", or variations of such words and phrases or state that certain actions, events or results "may", "could", "would", "might" or "will" be taken, occur or be achieved. Forward-looking statements or information involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Canopy Growth or its subsidiaries to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements or information contained in this news release. Examples of such statements include "aimed to reduce stigma in the workplace on the use of cannabis as a medicine", and "content will also include video resources featuring medical cannabis subject matter experts and fact sheets". Risks, uncertainties and other factors involved with forward-looking information could cause actual events, results, performance, prospects and opportunities to differ materially from those expressed or implied by such forward-looking information, including content development and such risks contained in the Company's annual information form dated June 24, 2019 and filed with Canadian securities regulators available on the Company's issuer profile on SEDAR at www.sedar.com. Although the Company believes that the assumptions and factors used in preparing the forward-looking information or forward-looking statements in this news release are reasonable, undue reliance should not be placed on such information and no assurance can be given that such events will occur in the disclosed time frames or at all. The forward-looking information and forward-looking statements included in this news release are made as of the date of this news release and the Company does not undertake an obligation to publicly update such forward-looking information or forward-looking information to reflect new information, subsequent events or otherwise unless required by applicable securities laws.

SOURCE Spectrum Therapeutics

Numbering You Won’t Stop the Opioid Crisis

by: Jane M. Orient, M.D.

People are dying all over the country from opioid overdoses. There’s a movement to have the antidote naloxoneavailable in all ambulances and even over the counter. This temporarily reverses the fatal effect of opioids, which stop the patient’s breathing. First responders themselves may need a dose because of contact with a tiny amount of fentanyl, an extremely potent narcotic, while attending a patient.

No, the fentanyl does not come from the patient’s bottle of legal prescription drugs.

Rep. Bill Foster (D-Ill.) introduced a proposal that he claims would “go a long way to fight the practice of doctor shopping for more prescription pain pills amid a deadly opioid crisis.” Doctor shopping “involves visiting multiple doctors.” Hardly new, this proposal, now passed by the House of Representatives as an amendment to a $99.4 billion Health and Human Services appropriations bill, lifts the ban on funding a Unique Patient Identifier (UPI).

The UPI is part of the Health Insurance Portability and Accountability Act (HIPAA) of 1996. You don’t have one yet because former congressman Ron Paul, M.D., (R-Tex,) sponsored a prohibition on funding it as part of a 1999 appropriations bill. Rep. Foster’s amendment repeals Dr. Paul’s prohibition.

So how is this 1996 idea supposed to work? And why would it be better than the Prescription Drug Monitoring Programs (PDMPs) now in effect in nearly every state? Every prescription for a controlled substance must be reported to the PDMP, and the doctor must check it before writing a prescription, to be sure the patient is not lying about having prescriptions from other doctors. This costly program that creates time-consuming hassles for doctors has not prevented opioid deaths.

PDMPs are ineffective because doctor shopping is not the cause of the problem. Only 2.5 percent of misused prescription pain medicine was obtained by doctor shopping. And this small percentage apparently increased after PDMPs. More than 97% of misused medications are obtained from a single physician—or from an illicit source. The spike in opioid deaths after 2013 was caused by illicit fentanyl, as Dr. John Lilly concludes from painstaking analysis of official data.

If Rep. Foster’s amendment is not removed, you might have to have a UPI to get legitimate medical care—“no card, no care”—but the drug cartel won’t mind. You can shop drug dealers as much as you like. There is a flood of fentanyl, mostly from Mexico or China, coming across our borders. Rep. Foster is apparently unaware of the armed lookouts protecting the smuggling routes in the Tucson sector. And once here, the drugs go to distributors—such as illegal aliens protected in sanctuary cities.

So, what about the other touted benefits of the UPI? “Specifically, assigning a unique number to a patient would give doctors a way to immediately identify a patient’s medical history,” said Rep. Mike Kelly (R-Pa.). He says it “would lower the cost of medical mix-ups due to misidentification.” His elderly father was nearly given the wrong medication.

To prevent medical errors, you need alert nurses and doctors—and the UPI is not going to fix the hazards of the electronic health record. The EHR, touted as the solution that will bring efficient, quality care, has created its own type of errors.

There is no guarantee that a UPI will improve access to the record, and critical information will still be buried in voluminous, repetitious data of dubious reliability, some of which may have been cut-and-pasted from another patient’s record. There may be critical gaps as patients withhold information they don’t want in a federal database. The new problem that brings the patient to the hospital won’t be in the old record—but may be the result of an old misdiagnosis that should be corrected instead of copied.

Patients need to be able to shop for doctors, especially if the one they have has not solved their problems. Some of them desperately need opioids, which are increasingly difficult to obtain. They do not need a UPI, and neither does their doctor.

The UPI is ideally suited for government tracking and control of all citizens. People like J. Edgar Hoover or Lois Lerner might find it very useful. But it would be the end of privacy, and the foundation for a national health data system.

###

Jane M. Orient, M.D. obtained her undergraduate degrees in chemistry and mathematics from the University of Arizona in Tucson, and her M.D. from Columbia University College of Physicians and Surgeons in 1974. She completed an internal medicine residency at Parkland Memorial Hospital and University of Arizona Affiliated Hospitals and then became an Instructor at the University of Arizona College of Medicine and a staff physician at the Tucson Veterans Administration Hospital. She has been in solo private practice since 1981 and has served as Executive Director of the Association of American Physicians and Surgeons (AAPS) since 1989. She is currently president of Doctors for Disaster Preparedness. She is the author of YOUR Doctor Is Not In: Healthy Skepticism about National Healthcare, and the second through fifth editions of Sapira's Art and Science of Bedside Diagnosis published by Wolters Kluwer. She authored books for schoolchildren, Professor Klugimkopf’s Old-Fashioned English Grammar and Professor Klugimkopf’s Spelling Method, published by Robinson Books, and coauthored two novels published as Kindle books, Neomorts and Moonshine. More than 100 of her papers have been published in the scientific and popular literature on a variety of subjects including risk assessment, natural and technological hazards and nonhazards, and medical economics and ethics. She is the editor of AAPS News, the Doctors for Disaster Preparedness Newsletter, and Civil Defense Perspectives, and is the managing editor of the Journal of American Physicians and Surgeons.

Newron’s commercialization partner Zambon and Valeo Pharma announce the launch of Onstryv® (safinamide) for Parkinson’s disease in Canada 

Milan, Italy and Montreal, Quebec – July 10, 2019 - Newron Pharmaceuticals S.p.A. (“Newron”) (SIX: NWRN, XETRA: NP5.XE), a biopharmaceutical company focused on the development of novel therapies for patients with diseases of the central and peripheral nervous system, is pleased to report that its partner Zambon S.p.A. and Valeo Pharma Inc. announced today the launch of Onstryv® (safinamide) for the treatment of Parkinson’s disease in Canada. 

“This marks another key milestone for Newron and its commercial partners in providing availability of safinamide in Canada for the treatment of patients suffering from Parkinson’s disease,” commented Newron CEO Stefan Weber. “Now, with the Canadian launch, safinamide is available across the North American region.”

The full text of the announcement from Zambon S.p.A and Valeo Pharma Inc. is as follows: 

Valeo Pharma Announces the Canadian Launch of Onstryvâ (Safinamide Tablets) for the Treatment of Parkinson’s Disease 

·      First new oral treatment for Parkinson’s Disease approved in over a decade

·      Parkinson’s Disease affects a growing number of Canadians with over 100,000 currently afflicted

·      Total Canadian market for Parkinson’s Disease drugs exceeds $100 million per year

MONTREAL, QUEBEC, July 10, 2019 – Valeo Pharma Inc. (CSE:VPH) (“Valeo”), a Canadian specialty pharmaceutical company with a primary focus on Neurodegenerative Diseases and Oncology, today announced the launch of Onstryv® (safinamide tablets) for the treatment of patients suffering from Parkinson’s Disease in Canada. Valeo has the exclusive rights to commercialize Onstryv® in Canada under a license agreement signed with Zambon S.p.A.

Valeo announced the approval of Onstryv® by Health Canada, on January 15, 2019, as an add-on therapy to a regimen that includes levodopa for the treatment of the signs and symptoms of idiopathic Parkinson’s Disease in patients experiencing “off” episodes.

Onstryvâ is a prescription medication now available at pharmacies across Canada and comes in 50mg and 100mg tablets. Valeo’s national sales team has launched a physician awareness and information campaign which is being supported by marketing and social media activities.

“The number of Canadians afflicted with Parkinson’s Disease is expected to grow by more than 50% over the next decade as the Canadian population ages,” said Steve Saviuk, Chief Executive Officer of Valeo. “Onstryv® is the first new oral treatment for Parkinson’s Disease to be approved in Canada in well over a decade. Many patients experience progressive symptom difficulties with currently available treatments, and we are proud to bring a new option to address this growing need for Canadian patients. Valeo is committed to building and supporting relationships with healthcare professionals, patients and other stakeholders to build awareness and ensure access to this new treatment for Parkinson’s Disease.” 

Roberto Tascione, CEO of Zambon said: “Since 1906, Zambon is committed to provide innovative medicines for patients and doctors and this launch is another significant step forward to fulfill our vision: Innovating Cure & Care to make patients’ lives better. Right now, with this important milestone, Safinamide has been launched in 14 European Union countries, Switzerland, U.S.A., Australia and Canada and has recently been approved in Brazil and Colombia.”

Parkinson’s Disease is a progressive neurological disease involving the loss of dopamine-producing neurons in the brain. While tremors are the best-known symptom, Parkinson’s Disease also causes other symptoms including slowed movement, rigid muscles, impaired posture and balance, speech and writing difficulties. On a per capita basis, Canada has amongst the highest incidences of Parkinson’s Disease in the world and the number of patients is expected to grow significantly over the next thirty years as the median population age increases. 

About Onstryv® (safinamide)                                                                                                                                                                                                                                                                                                                           

Safinamide, known as Onstryv® in Canada and Xadago® in the rest of the world, is a new chemical entity with a unique mode of action including selective and reversible MAO-B-inhibition. Clinical trials have established its efficacy in controlling motor symptoms and motor complications in the short term, maintaining this effect over 2 years. Results from 24-month double-blind controlled studies suggest that safinamide shows statistically significant effects on motor 

fluctuations (ON/OFF time) without increasing the risk of developing troublesome dyskinesia. Onstryv® is a once-daily dose and has no diet restrictions due to its high MAO-B/MAO-A selectivity. Zambon acquired rights from Newron Pharmaceuticals (www.newron.com) to develop and commercialize Xadago® globally, excluding Japan and other key Asian territories where Meiji Seika Pharma has the rights to develop and commercialize safinamide. The rights to commercialize Xadago® in the USA have been granted to US WorldMeds, by Zambon. 

About Valeo Pharma                                                                                                                                                                

Valeo Pharma is a specialty pharmaceutical company dedicated to the commercialization of innovative prescription products in Canada. With a focus on Neurodegenerative Diseases, Oncology, Women’s Health and Hospital Specialty Products, Valeo Pharma has a growing portfolio of innovative products and the full infrastructure to properly manage these products through all stages of commercialization. Headquartered in Kirkland, Quebec, Valeo Pharma has all capabilities internally to register and market health care solutions for Canadian patients. For more information, please visit www.valeopharma.com.

About Zambon 

Zambon is a multinational pharmaceutical and fine-chemical company that focuses on innovation and development with the aim to improve the quality of people’s health and patients’ lives. Based on a valuable heritage but strongly focused on the future, its goal is to improve people’s health through the development of innovative and quality medicines. Zambon products are commercialized in 86 countries. The company has 20 subsidiaries in three different Continents – Europe, America and Asia – and owns manufacturing units in Italy, Switzerland, France, China and Brazil. The company today has a strong focus on the treatment of rare diseases such as Cystic Fibrosis and specialties, such as Parkinson’s disease, and it’s well-established in 3 therapeutic areas: respiratory, pain and women’s care. Zambon was established in 1906 in Italy and today counts around 2,700 employees all over the world. For details on Zambon please visit www.zambon.com.

Forward Looking Statements

This press release contains forward-looking statements about Valeo’s objectives, strategies and businesses that involve risks and uncertainties. These statements are “forward-looking” because they are based on our current expectations about the markets we operate in and on various estimates and assumptions. Actual events or results may differ materially from those anticipated in these forward-looking statements if known or unknown risks affect our business, or if our estimates or assumptions turn out to be inaccurate.

NEITHER THE CANADIAN SECURITIES EXCHANGE NOR ITS REGULATIONS SERVICES PROVIDER HAVE REVIEWED OR ACCEPT RESPONSIBILITY FOR THE ADEQUACY OR ACCURACY OF THIS RELEASE.

New Committee Brings Diverse Patient, Family, and Caregiver Voices to CADTH

OTTAWA, July 10, 2019 /CNW/ - Following a nationwide call for nominations, CADTH is pleased to announce the membership of its new Patient and Community Advisory Committee. 

Twelve individuals from across the country have been invited to join the committee as inaugural members. Committee members are patients or family caregivers and reflect the diversity of people and communities across Canada. Members will advise CADTH on all areas of the agency's work from the perspective of individuals using the Canadian health care system.

"This important committee ensures that CADTH is even more inclusive, transparent, and accountable to patients, families, and caregivers," said Dr. Brian O'Rourke, President and CEO of CADTH. "Working closely with patients and communities helps us better serve the health care decision-makers who rely on CADTH to make equitable choices about the appropriate use of health technologies."

The committee will meet four times a year and report to the President and CEO of CADTH. 

The members of the CADTH Patient and Community Advisory Committee are:

  • Marilyn Barrett, the Director of the Health & Wellness Centre at the University of Prince Edward Island. She is a retired community nurse and the former Director of Primary Care for Health for Health PEI. Marilyn has been a caregiver to multiple family members, which required out-of-province care for health treatment. 
  • Jonah Dupuis, a community pharmacist in Northwestern Ontario, who has previously served as a councillor on Nipigon's Town Council and the director of pharmacy at the Nipigon District Memorial Hospital. Jonah is a proud member of the Anishinabek Nation and currently works in a travelling health team that delivers primary health care directly to First Nations communities. He also is a caregiver for his son who lives with a rare genetic condition. 
  • Lilian Hulme-Smith, a retired public servant, who spent the bulk of her career in social and supportive housing administration and risk management. She is a member of the Mackenzie Health Mackenzie Richmond Hill Hospital Patient Advisory Committee and Medication Safety Committee, as well as a patient advisor at the Central Local Health Integration Network. Lilian lives with primary-progressive multiple sclerosis. 
  • Beth Kidd, the Executive Director of Health Coalition of Alberta, representing more than 90 health charities, as well as individuals, that advocate for improved access to care and greater patient engagement. Beth lives with chronic migraines and is a Board member of Migraine Canada and Dementia Network Calgary. 
  • Marlee McGuire, a medical anthropologist and a doctoral student at the University of British Columbia, where her research focuses on the politics of rare diseases though multi-stakeholder perspectives, including patient and public payer perspectives. Marlee has navigated systems around addiction and chronic conditions as a family member. 
  • David McMullen, a retired engineer and manager with Ontario Power Generation. David has been a multiple myeloma patient since 2012. He is very active with Myeloma Canada, contributing to its objectives of patient and caregiver education and support, research, access to treatments, and awareness. David was the founding Chair of the Myeloma Canada Patient Advisory Council. He has leadership and advisory roles in several myeloma patient support groups. He is also a patient representative in the Canadian Cancer Trials Group. 
  • Devan Nambiar, MSc., an education and training specialist on LGBT2SQ+ health and HIV care for organizations, clinicians, and allied health professionals through Rainbow Health Ontario, Sherbourne Health, with his own consultancy, GHIS.ca. He co-wrote four HIV national publications at CATIE, has served on the Community Advisory Committee for the Canadian Institutes of Health Research Canadian HIV Trials Network, HIV Research Ethics Board at the University of Toronto, as well as on the boards of the Alliance for South Asian AIDS Prevention and CTAC. Devan is a South Asian gay man who has been living with HIV for 34 years. 
  • Paula Orecklin, a disability advocate who shares her experiences living with a disability with youth as a Rick Hansen Foundation Ambassador. She is also a patient and family advisor with the Winnipeg Regional Health Authority. Paula lives with chronic pain and is involved in the DAWN‒DisAbled Women's Network and the Manitoba League of Persons with Disabilities. 
  • Marney Paradis, the Executive Director of Habitat for Humanity Yukon and a Doctor of Education candidate at the University of British Columbia, where her philosophical inquiry focuses on the intersection of anti-oppressive, community-based, and spiritual support systems within frameworks of health advocacy. Marney has a son who lives with type 1 diabetes and she is the President of Yukon T1D Support Network — a non-profit group she helped found to provide education, advocacy, and support to people in Yukon with type 1 diabetes. 
  • Zal Press, the executive director of Patient Commando, an organization dedicated to lifting the veil of silence that so often accompanies the onset of illness. He was the founding co-Chair of The Beryl Institute Global Patient and Family Advisory Board, which works to ensure that the voices of patients and families are a central consideration in the strategic direction and offerings of the Institute. Zal has lived with Crohn disease for more than 38 years. He is passionate about illustrating the need for improved health care policy and delivery by sharing stories that enrich our appreciation of the lived illness experience. 
  • Mary Reeves, a retired education administrator and mediator, and an active volunteer in her community. She is a founding member of the Grand Bay-Westfield Age Friendly Communities Committee, and a past Board member of the Sophia Recovery Centre — a support centre for women recovering from addictions. Mary lives with osteoarthritis and vision impairment, and is aware of the challenges of staying independent as she and her husband age. 
  • Sarah Sandusky, a fundraising and communications specialist with extensive experience working with non-profit organizations focused on homelessness, addiction, mental illness, health, education, and human rights. She previously held leadership roles with the Dr. Peter AIDS Foundation in Vancouver, BC Civil Liberties Association, Street League in the UK, and Eva's Initiatives for Homeless Youth in Toronto. Sarah is now a freelance facilitator and fundraising strategist based in British Columbia. She is a Board member of Pain BC and has experienced the impact of chronic pain both personally and professionally.

Engaging with Canadian patients and communities is a strategic priority for CADTH. CADTH offers many opportunities for patients and their families, caregivers, advocacy groups, and communities to read, contribute to, and shape its work. Information about these opportunities is available on the CADTH Patient and Community Engagement Web pages.

About CADTH
CADTH is an independent, not-for-profit organization responsible for providing Canada's health care decision-makers with objective evidence to help make informed decisions about the optimal use of drugs and medical devices in our health care system. CADTH receives funding from Canada's federal, provincial, and territorial governments, with the exception of Quebec.

SOURCE Canadian Agency for Drugs and Technologies in Health (CADTH)