In the Heart of Cannabis “Wine Country” This Cultivator Leads the Pack

Santa Barbara-based Autumn Brands receives first Provisional Annual Cultivation License in the region, solidifies reputation as top producer

LOS ANGELES, California – (April 2nd, 2019): Autumn Brands receives the first California Provisional Annual Cultivation license in Santa Barbara County. Known for its holistic focus and artisanal approach, the 50% woman-owned company has earned a reputation for producing powerfully potent strains of pesticide-free cannabis. The recent licensure, which helps the California Department of Food and Agriculture weed out mediocre producers, signifies Autumn Brands’ commitment to maintaining the highest quality standards while further solidifying the company’s name among the who’s who of top notch cultivators.

In order to achieve licensure, Autumn Brands worked diligently to verify compliance with the state of California’s rigorous regulations for the commercial growth and sale of cannabis. In addition to obtaining approval from local regulatory agencies, the company reached an agreement with the California and Central Coast Water Board, California Fish and Wildlife, and confirmed a proactive waste management plan. Additionally, Autumn Brands’ owners evidenced clean background records and agreed, under penalty of perjury, to adhere to all state regulations moving forward.

Experience the exceptional flavor and aroma of hand-selected, sun-grown buds, each hang-dried and hand-trimmed and cured to preserve maximum potency and full healing benefits. Visit www.AutumnBrands.com to explore their full selection of premium flower and pre-rolls. New this month, browse cartridges pre-filled with estate-grown cannabis oils. Learn more about the company and follow on Instagram @AutumnBrands for new product releases and updates.

About Autumn Brands:

Autumn Brands is a licensed California cannabis cultivator dedicated to the synergy of health and wellness. The Autumn Brands’ family farm started in Holland more than a century ago, and today, sixth-generation farmers apply the same expertise garnered in growing the world’s finest tulips to producing pure and potent strains of cannabis in sunny, coastal Santa Barbara County. Autumn Brands is proud to be 50 percent woman-owned, free of pesticides and other harmful chemicals. For more information, visit www.autumnbrands.com or email leighanne@anderson-pr.com.

Chef Paula Shoyer Offers Five Passover Desserts So Good You Will Want to Make Year-round!

Florentine Bars Recipe excerpted from The New Passover Menu20 square bars or 32 triangles
Ingredients
1 cup confectioners' sugar3 large egg whiteszest of one large orange (or 2 teaspoons juice)1/4 cup dried cranberries, chopped into ¼ inch pieces1 1/3 cups sliced almonds (blanched or with skin)1 cup dark or white chocolate chipsvegetable oil for greasing pan
Preheat oven to 325°F
Grease a 9 X 13-inch pan with vegetable oil. Press in a piece of parchment paper large enough to cover the bottom and go an inch up the sides of the pan, making sure you press it into the corners. Grease the top of the parchment.
In a medium bowl, whisk together the confectioners' sugar, egg whites and orange zest. Use a silicone spatula to gently mix in nuts and chopped cranberries, being careful not to crush the nuts. Scoop into the pan and use the spatula or your hands to spread evenly in the bottom of the pan. The easiest way to do this is to push the batter into the edges and corners first and then fill in the middle. You will have a thin nut layer.
Bake 25 minutes, or until nuts are golden. Let cool one hour. Pull up the parchment to lift the bar out of the pan. Place another piece of parchment on top and then turn the bar over onto the new parchment. Peel off the bottom parchment.
Melt the chocolate chips either over a double boiler or in the microwave oven in for 45 seconds, stir, melt another 30 seconds, stir and then for 15 seconds more, if needed, until melted. Use a spatula to spread the chocolate on the bottom of the bar. If desired, you can use a serrated knife to make lines in the chocolate to decorate it. Slide the parchment and bars onto a cookie sheet and place in the freezer for 30 minutes to firm up.
Cut into squares, triangles or rectangular bars. Store in an airtight container in the fridge for up to five days or freeze for up to three months
Lemon Quinoa Cakewww.kosherbaker.comServes 12Prep Time: 20 minutes Bake Time: 15 minutes to cook quinoa, 65 minutes to bake cake Advance Prep: May be made 3 days in advance or frozen
Cake¾ cup quinoa1½ cups waterCooking spray or 2 tablespoons oil2 tablespoons lemon zest, from 2-3 large lemons½ cup fresh lemon juice, from 2-3 large lemons4 large eggs1 teaspoon pure vanilla extract (or other vanilla if for Passover)¾ cup coconut oil1 ¼ cups sugar1 cup almond flour¼ cup coconut flour, plus 2-3 tablespoon to dust bundt pan2 teaspoons baking powder1 teaspoon baking soda½ teaspoon salt
Glaze (optional)1 cup confectioners' sugar
2 tablespoons fresh lemon juice (from 1-2 lemons)
Place the quinoa and water into a small saucepan and bring it to a boil over medium heat. Reduce the heat to low, cover the saucepan, and cook the quinoa for 15 to 18 minutes, or until all the liquid has been absorbed. Let sit for 5 minutes off the stove-top. The quinoa may be made 2 days in advance and stored in the fridge.
Preheat the oven to 350°F. Use cooking spray or oil to grease a 12-cup Bundt pan. Sprinkle 1 to 2 tablespoons coconut flour, or more if needed, over the entire greased pan and then shake the pan all around to cover and then tap out the excess.
Place the quinoa in the bowl of a food processor. Add the lemon zest and juice, eggs, vanilla, oil, sugar, almond flour, coconut flour, baking powder, baking soda and salt and process until the mixture is very smooth, about 2 minutes.
Pour the batter into the prepared Bundt pan and bake it for 1 hour, or longer, until a skewer inserted into the cake comes out clean.
Let the cake cool for 30 minutes and then remove it gently from the pan onto a wire cooling rack.
To make the glaze, place the confectioners' sugar into a bowl and add 1 tablespoon of lemon juice and whisk well. Add more juice, a teaspoon at a time, until you have a thick glaze. Drizzle or pour over the cake.

Chocolate Quinoa CakeRecipe excerpted from The Healthy Jewish KitchenServes 12 Prep Time: 20 minutesBake Time:15 minutes to cook quinoa, 50 minutes to bake cakeAdvance Prep: May be made 3 days in advance or frozenEquipment: Measuring cups and spoons, small saucepan with lid, 12-cup (2.8L) Bundt pan, food processor, medium microwave-safe bowl or double boiler, silicone spatula, wooden kebab skewer, wire cooling rack, large microwave-safe bowl, whisk
Cake¾ cup (130g) quinoa1½ cups (360ml) waterCooking spray2 tablespoons potato starch1/3 cup (80ml) orange juice (from 1 orange)4 large eggs2 teaspoons pure vanilla extract (or other vanilla if for Passover)¾ cup (180ml) coconut oil1½ cups (300g) sugar1 cup (80g) dark unsweetened cocoa2 teaspoons baking powder½ teaspoon salt2 ounces (55g) bittersweet chocolateFresh raspberries, for garnish (optional)
Glaze (Optional)5 ounces (140g) bittersweet chocolate1 tablespoon sunflower or safflower oil1 teaspoon pure vanilla extract (or other vanilla if for Passover)
Place the quinoa and water into a small saucepan and bring it to a boil over medium heat. Reduce the heat to low, cover the saucepan, and cook the quinoa for 15 minutes, or until all the liquid has been absorbed. Set the pan aside. The quinoa may be made 1 day in advance.
Preheat the oven to 350°F (180°C). Use cooking spray to grease a 12-cup (2.8L) Bundt pan. Sprinkle the potato starch over the greased pan and then shake the pan to remove any excess starch.
Place the quinoa in the bowl of a food processor. Add the orange juice, eggs, vanilla, oil, sugar, cocoa, baking powder, and salt and process until the mixture is very smooth.Melt the chocolate over a double boiler, or place in a medium microwave-safe bowl, and put in a microwave for 45 seconds, stirring and then heating the chocolate for another 30 seconds, until it is melted. Add the chocolate to the quinoa batter and process until well mixed. Pour the batter into the prepared Bundt pan and bake it for 50 minutes, or until a skewer inserted into the cake comes out clean.
Let the cake cool for 10 minutes and then remove it gently from the pan. Let it cool on a wire cooling rack.
To make the glaze, melt the chocolate in a large microwave-safe bowl in the microwave (see above) or over a double boiler. Add the oil and vanilla and whisk well. Let the glaze sit for 5 minutes and then whisk it again. Use a silicone spatula to spread the glaze all over the cake.Keto Chocolate Avocado Cakewww.thekosherbaker.comMakes one 8-inch round cake
Cake1 ½ cups almond flour¾ cup dark cocoa, plus 1 tablespoon for greasing pan¼ cup coconut flour*½ cup xylitol1 teaspoon baking powder1 teaspoon baking soda¼ teaspoon salt½ cup coconut cream, from canned coconut milk½ cup almond milk3 large eggs1 tablespoon coconut oil, plus 1 teaspoon for greasing pan1 teaspoon vanilla1 large ripe avocado
Ganache5 tablespoons boiling water½ cup dark cocoa¼ cup xylitol½ cup coconut cream 1 teaspoon vanilla
Preheat oven to 350°F.
Grease an 8-inch round pan with 1 teaspoon coconut oil. Add 2 to 3 teaspoons cocoa and shake all around to dust the bottom and sides. Tap out excess. Set aside.
In a mixing bowl, whisk together the almond flour, cocoa, coconut flour, xylitol, baking powder, baking soda and salt.
Place the coconut cream, almond milk, eggs, coconut oil, vanilla and avocado into a food processor or blender and blend for two full minutes, scraping down the sides a few times, so that the mixture is completely smooth.
Add the wet ingredients to the dry ingredients and whisk together. Use a silicone spatula to scrape the batter into the prepared pan and smooth the top.
Bake for 30 to 35 minutes, or until a toothpick inserted comes out clean. Let cool for 10 minutes and the remove to a wire rack.
To prepare the ganache topping, place the cocoa and xylitol into a small bowl. Add the boiling water and whisk well. Add the coconut cream and vanilla and mix well. Spread all over the top of the cake.
*can be substituted with almond flourTriple Chocolate Biscottiwww.thekosherbaker.comYield: 24-36 cookies
Prep Time: 10 minutesCook Time: 44 minutesStorage: room temperature for 5 daysAdvanced Prep: May be frozen
Ingredients

4 ounces (115g) bittersweet chocolate, broken

into pieces

1 cup (200g) sugar

1/2 cup (120ml) vegetable oil

2 large eggs

3 tablespoons (40g) vanilla sugar

1/2 cup (40g) unsweetened cocoa

1 tablespoon potato starch

1 1/2 cups (180g) ground almonds

1/4 teaspoon salt

1 cup (170g) semi-sweet chocolate chipsPreparation DirectionsPreheat oven to 350°F (180°C)Line a jelly roll pan or cookie sheet with parchment paper.
Melt the chocolate using one of the methods described in the box below. Remove the chocolate from the heat source, add the sugar and oil, and whisk well. Add the eggs and mix. Add the vanilla sugar, cocoa, potato starch, ground almonds, and salt and mix well. Add the chocolate chips and mix to distribute them.
Divide the dough in half and shape into two loaves, each about 9 x 3 inches (23 x 7.5cm). Place both loaves on the lined jelly roll pan and bake for 30 minutes. Let the loaves cool for 10 minutes (do not turn off the oven). Cut each loaf crosswise into 3/4- to 1-inch-thick (2- to 2.5-cm) slices.
Place the cookies, cut side up, on a parchment-covered cookie sheet (or the jelly roll pan again). Bake for another 14 minutes, or until the cookies are firm to the touch on the outside but still feel soft on the inside. Check them after 10 to 12 minutes so that you don't over-bake the cookies.
Let cool for 5 minutes on the pan and then slide the parchment and cookies onto a cooling rack to cool completely.

Olympian connects and empowers Canadians through the power of storytelling

UNSINKABLE portal spotlights lessons of hope and courage

Toronto, ON, April 2, 2019 – Real-life stories of indomitable people who have faced adversity and triumphed will be profiled on a new web portal that launches April 3. UNSINKABLE is a labour of love from four-time Olympian and child and mental health advocate, Silken Laumann, in the form of a story-sharing platform that seeks to connect and empower Canadians in their own mental, physical and spiritual health (WeAreUnsinkable.com).

Laumann created UNSINKABLE after years of listening to Canadians’ remarkable stories of courage and resilience. Her goal is to share these stories so that they can be a resource for others who may be struggling. In doing so, people have the opportunity to connect with the stories and articles that might help them to feel like they’re not alone while de-stigmatizing the conversation around mental health challenges. UNSINKABLE is also a valuable resource for anyone seeking inspiration and/or helpful tips from trusted health experts.

“Since my accident and writing my book about my own mental health struggles, people have approached me to share their own personal stories about overcoming physical and mental health challenges. It makes absolute sense to me that these things are connected – in order to overcome something physical, you need to be mentally strong,” said Laumann. “This is a forum for people to keep sharing their stories so others can learn and feel connected. We need stories that are helpful and hopeful…a celebration of how strong people are. There is a demand for a platform that shares lived experience and this is it.”

Some of the stories include a Vancouver girl who battled a neuropsychiatric disorder before the age of 8, a young man who grew up gay in a small village in Newfoundland and Labrador, a young woman from Ottawa who survived being lit on fire, a Toronto woman in her 20s who was born HIV positive, along with many others. The platform also features stories from notable Canadians such as competitive swimmer and Olympic medalist, Mark Tewksbury, and mental health advocate, Margaret Trudeau. In addition, there are inspiring stories from everyday Canadians who have fought to advance awareness of mental and physical health issues.

One of the Canadians profiled is Maria Estrada, who immigrated to Canada from Peru with her family as a young girl. She grew up with mental illness that resulted in self-harm, multiple suicide attempts and addiction. As the child of a single working mother who couldn’t acknowledge what was happening to Maria because of cultural barriers, Estrada had to navigate her own way through the medical system and advocate for the supports she needed. She now works as a counsellor and public speaker to help others who face similar challenges.

“When I was younger, no one ever talked about mental illness. I felt alone for so many years and tried to commit suicide several times. When I turned to the internet, all I could find was negative, dark material about eating disorders and self-harm,” Estrada said. “This online platform is a safe place that offers hope. Reading stories about other people like you makes you feel like you’re not alone and that’s a huge help.”

UNSINKABLE also offers expert perspectives on issues facing the health of Canadians from healthcare and wellness professionals including Dr. Jillian Roberts, registered nutritionist Lauren Follett, registered psychotherapist Dr. Suzanne Wiseman, as well as health coaches focused on personal training, yoga, meal planning and more.

“I am honoured to be a part of this powerful project to help others heal and become their best selves. A large part of my work as a psychologist is focused on teaching children, teens and adults how to develop resilience. Silken is the embodiment of resilience and grit and I look forward to all that will be achieved in this project,” said Dr. Jillian Roberts, a clinical psychologist who will provide regular content to the platform.

About Silken Laumann

Silken Laumann is a four-time Olympian and one of Canada’s most inspirational leaders, a bestselling author, and a child and mental health advocate. Silken’s Olympic story is legendary and inspirational. As reigning world champion, Silken fought back from a devastating rowing injury, to win a bronze medal in the 1992 Summer Olympics. Silken speaks candidly about her athletic success and triumph over physical adversity, but also the intense personal challenges of her past and the fierce determination she applies to living a bold, loving and successful life today.

About UNSINKABLE

UNSINKABLE is a not-for-profit project with the goal of collaborating with national and regional health promotion and mental health organizations. UNSINKABLE partners with GoodLife Fitness for expertise in physical activity and mental wellness. To check out UNSINKABLE, please visit WeAreUnsinkable.com or follow @WeAreUnsinkable (Facebook), @unsinkablestories (Instagram) or @BeingUnsinkable (Twitter).

Almost two thirds of Canadian men aged 18-34 don't know their testicular cancer risk

Almost two thirds (57%) of 18-34 year-old men in Canada don't know they are in the age group most at risk of being diagnosed with testicular cancer
54% of 18-34 year-old men in Canada say they that they have no idea or are unsure how to perform a testicular self-examination.
Not all bad news – of all Canadian men, 27% say that they have checked themselves for signs of testicular cancer in the last month

TORONTO, April 2, 2019 /CNW/ - Almost two thirds (57%) of men in Canada aged between 18-34 don't know that they are in the age group most at risk of getting testicular cancer, according to new researchⁱ from leading global men's health charity, the Movember Foundation.

Testicular cancer is the most common cancer in young men, and the charity is now urging men in the at-risk age group to carry out regular self-checks as early diagnosis is key to successful treatment.

The Movember Foundation's Global Director of Testicular Cancer, Sam Gledhill, said; "The fact that so many men are unaware that they are in the highest-risk age group is very worrying. There's a widespread assumption that it's a disease that predominantly affects older men but that's just not the case. Testicular cancer strikes early so checking regularly and knowing what to look for is crucial."

However, the poll of 474 Canadian men conducted by YouGov, also found that 57% of men in the at-risk age group (aged 18-34) didn't know or are unsure how to perform a testicular self-examination.

"If you're a guy in your 20s or 30s, you should definitely be getting to know your testicles a little better. What they look like, what they feel like and what's normal for you down there.

The shower is a great place to start because the warmth relaxes the scrotum, making the exam easier. Around once a month, when you're in the shower, gently roll one testicle at a time between your thumb and fingers. If you notice any changes, don't panic, it doesn't necessarily mean you have cancer but you should definitely get it checked out." – Sam Gledhill

The survey results weren't all bad news for Canadian men, with 27% claiming they had checked their testicles for signs of the disease in the last month¹. After being prompted by the survey, almost two thirds revealed they were either 'very likely' or 'fairly likely' to perform a self-check during the next six weeks.

Testicular cancer will often present as a lump or pain in the testicle, an increase in size or a change in the way a testicle feels – although these symptoms can be vague or may not be the same for everyone.

Those most at risk are men who had undescended testes at birth, or those with a relative who has diagnosed with testicular cancer.

Although survival rates are high (95 per cent), one in 20 cases are fatal. More than 8,600 men die from testicular cancer globally each year. The Movember Foundation has pledged to halve the numbers of men dying from testicular cancer by 2030.

This April, #KnowThyNuts for Testicular Cancer Awareness Month. For more information visit: www.movember.com/knowthynuts or https://truenth-tc.org/

Notes to editors:

Images are available to download from https://ca.movember.com/media-room/photos-graphics

About the Movember Foundation

The Movember Foundation is the leading global men's health charity.

The Foundation raises funds to deliver innovative, breakthrough research and support programmes that enable men to live happier, healthier and longer lives. Committed to disrupting the status quo, millions have joined the movement, helping fund over 1,200 projects focusing on prostate cancer, testicular cancer and suicide prevention.

In addition to tackling key health issues faced by men, the Foundation is working to encourage men to stay healthy in all areas of their life, with a focus on men staying socially connected and becoming more open to discussing their health and significant moments in their lives.

The Foundation's vision is to have an everlasting impact on the face of men's health. Join the movement at Movember.com.

________________________

ⁱ All figures, unless otherwise stated, are from YouGov Plc. Total sample size was 474 men in Canada. Fieldwork was undertaken between 7th – 12th February 2019. The survey was carried out online. The figures have been weighted and are representative of all men (aged 18+) in each market.

SOURCE Movember Canada

Anxiety, It's Time to Go: New Book Ditches the Psychobabble to Remove Anxiety…for Good!

Kevin Mullin’s ‘Anxiety, It’s Time to Go’ calls on the author’s vast experience as an NLP practitioner to help readers identify the root of their anxiety and not only remove it…but rid it for good. Using a series of proven techniques, this breakthrough guide could just be the most comprehensive and actionable self-help book on the market. One critic recently wrote, “It was all so simple, it made sense and it worked!!!”

Contact:

Kevin Mullin

Email: kevin@serenitynlp.com

Telephone: 07788119374

*Press Review Copies are Available from the Media Contact

*Kevin Mullin is Available for Interviews

FOR IMMEDIATE RELEASE

Ayr, Scotland – Those who suffer from anxiety and its related disorders understand it isn’t just disheartening, but an often-debilitating, life-destroying condition. And even worse, there’s a flood of books on the market conveying half-baked techniques that rarely actually work.

But that all now stops thanks to NLP practitioner Kevin Mullin and his new book, ‘Anxiety, It’s Time to Go’.

Just like the title, Mullins’ breakthrough text marks anxiety’s “grand finale” for its sufferers around the world, as they prepare to step into a new life free of the condition.

Synopsis:

Anxiety, It's Time to Go is not just another self-help book. It is 'the' self-help book. It uses cutting-edge tried and tested methods that have been used time and time again to remove anxiety from people each and every day. Anxiety, It's Time to Go will explain everything in simple terms and then show you exactly how to combat the things that hurt and control us when it comes to anxiety. The easy-to-follow exercise and instructions have been made straightforward without all the psychobabble that most people use. We say it as it is and then show you exactly how to remove it. This might just be the best thing you have done when it comes to beating crippling anxiety once and for all.

“The over-riding goal with this book was to make it as straightforward and actionable as possible, with no fluff and no BS,” explains the author. “The fact of the matter is that anxiety is an epidemic in society these days and, unless someone steps in to do something about it, it’s going to continue destroying lives around the world.”

Continuing, “You need no prior understanding of NLP to use my book to change your life, and you also don’t need to fully understand your own anxiety. If you suffer, or even think you do, what I have to teach will radically improve your mental health and the overall quality of your life. Get a copy today!”

Reviews have been extremely positive. One reader writes, “I was given the book to read and I loved it. It was one of those books that I did not want to put down but equally did not want to finish, as I was enjoying it too much (like saving a new dress 'for best'). It was all so simple, it made sense and it worked!!! Now, I am not going to elaborate more, because I am now too busy living anxiety-free! Too busy enjoying life. Planning life. Too happy to even think about the old me who wasted so much time feeling anxious, stressed, miserable, not wanting to be here. So, read it for yourself.”

‘Anxiety, Its Time to Go’ is available now: https://amzn.to/2DvLkDQ.

About the Author:

Kevin Mullin enlisted in the British Army aged fifteen years and eight months. He served in several conflict areas and operations around the globe, then at the age of thirty-four, he left the service and became a private military operator. Kevin was contracted to the United States Department of Defense, securing and protecting US Military bases and assets in Afghanistan. Kevin worked there for four years before moving to one of the most valuable targets in Afghanistan in the heart of Kabul – The Serena Hotel. Kevin studied NLP within the British Army and gained a wealth of knowledge and experience, training the trainers in the methods of approaches to NLP. Having suffered the loss of both his brother and mother, he was crippled with anxiety for many years. Kevin searched relentlessly for new, dynamic ways to beat it.

Having taken an apprenticeship with Ali Campbell, Kevin finally found what he was looking for. He understudied and role modelled Ali to great effect. In June 2017, Kevin opened his very own NLP practice based in Central Scotland. The practice has received rave reviews about Kevin’s new, dynamic and direct approach. He has helped thousands of clients become anxiety-free. Kevin has gained plaudits from Italy, Dubai and America for his dynamic and enthusiastic approach to motivational speaking and helping businesses and organisations flourish and grow. He is also a full-time parent. He raises his children with the approach he takes in life and in his crusade to help everyone in the battle with anxiety. Drive, determination and a vigour unparalleled in this modern age.

2019 Canada Gairdner Awards Recognize World-renowned Scientists for Transformative Contributions to Research that Impact Human Health

TORONTO, April 2, 2019 /CNW/ - On the 60^th anniversary of the Canada Gairdner Awards, the Gairdner Foundation is pleased to announce the 2019 Canada Gairdner Award laureates, recognizing some of the world's most significant biomedical research and discoveries. Laureates receive a $100,000 cash honorarium and are formally presented with their awards on October 24, 2019 at the annual Canada Gairdner Awards Gala in Toronto.

2019 Canada Gairdner International Award
The five 2019 Canada Gairdner International Award laureates are recognized for seminal discoveries or contributions to biomedical science:

Dr. Susan Band Horwitz, Ph.D.
Distinguished Professor, Rose C. Falkenstein Chair in Cancer Research, Department of Molecular Pharmacology, Albert Einstein College of Medicine, New York

Awarded "For defining novel mechanisms of action and resistance of drugs of natural product origin, most significantly Taxol^®, and promoting their use for treatment of cancer"

The Work: Dr. Susan Band Horwitz is best known for elucidating the mechanism of action of Taxol®, a natural product obtained from the yew tree, Taxus brevifolia. Horwitz discovered that Taxol® binds to microtubules in cells, stabilizing them, thereby leading to cell cycle arrest and subsequent tumor cell death. This body of work enabled the successful translation of Taxol® into the clinic. It is one of the most frequently prescribed drugs in the world for the treatment of ovarian, breast and lung cancer.

The Impact: Dr. Horwitz' research played a crucial role in encouraging the development of Taxol^® for use in the clinic. Although no one was interested in Taxol^®when she began her studies, today it is an important antitumor drug approved by the FDA for the treatment of ovarian, breast and lung carcinomas, as well as Kaposi's Sarcoma. The drug has been given to millions of cancer patients worldwide. Taxol^® also is used in the preparation of stents for cardiac disease. In addition, Taxol^® has proven to be an indispensable tool for scientists interested in microtubule structure, dynamics, and function.

Dr. Ronald Vale, Ph.D.
Professor, Cellular Molecular Pharmacology University of California, San Francisco;
Investigator, Howard Hughes Medical Institute

Awarded "For the landmark discovery of the motor protein kinesin and pioneering the understanding of its mechanism of action in driving cellular movement processes including cell division and intracellular transport"

The Work: Vale's research has focused on molecular motor proteins, nature's nano-scale machines that convert chemical energy into directed movement. Vale began by asking how materials are transported in neurons, which are highly elongated cells that extend up to a meter in humans. Using squid as a model system, he developed a test-tube system to study this cellular transport process. This work led to the discovery of a new motility-producing molecule, which was named "kinesin". Vale's laboratory then uncovered the molecular choreography that enables this 1/millionth of an inch machine to drive movement. Collectively, Vale's work has informed, at a broad level, how living organisms generate motion.

The Impact: Dr. Vale's discovery of kinesin and molecular motors transformed the field of cell biology, placing a spotlight on the study of motor proteins. His research has illuminated the fundamental principles that underlie biological motility, an essential attribute of living organisms. The discovery of kinesin led to new tools for studying protein machines more broadly, sparked studies that connected motor proteins to innumerable cellular processes, and contributed to the realization that motility defects underlie various diseases of the nervous system, heart, and other organ systems.

Dr. Timothy A. Springer, Ph.D.
Latham Family Professor of Biological Chemistry and Molecular Pharmacology, Professor of Medicine, Harvard Medical School and Boston Children's Hospital; Chairman, Institute for Protein Innovation

Awarded "For discovery of the first immune system adhesion molecules, elucidation of their roles in antigen recognition and leukocyte homing, and translation of these discoveries into therapeutics for autoimmune diseases"

The Work: Dr. Timothy Springer's work has changed understanding of cell-to-cell interactions that control immune responses and the movement of leukocyte subsets out of the vasculature into tissues. He discovered the first examples of cell recognition receptors and counter-receptors and the first family of integrins. He subsequently showed molecularly how integrins transmit signals between the exterior and interior of cells and enable cell movement. He opened the way for the first therapeutic use of antibodies to cell-cell recognition receptors to treat autoimmune diseases.

The Impact: Dr. Springer's discoveries and world-renowned work have transformed the fields of cell biology and immunology. His discoveries and entrepreneurship have led to an important new class of therapeutics for multiple autoimmune diseases including Psoriasis, Multiple Sclerosis, Ulcerative Colitis, Crohn's Disease and cancer.

Dr. Bruce Stillman, Ph.D., FRS
President, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York

Dr. John F.X. Diffley, Ph.D., FRS FMedSci
Associate Research Director, The Francis Crick Institute, London, U.K.

Awarded "For their pioneering research on the eukaryotic DNA replication cycles including initiation, regulation and responses to DNA damage"

Dr. Stillman:

The Work: Dr. Stillman's research focuses on how chromosomes, including both DNA and chromosome-associated proteins, are duplicated in human cells and in yeast, thereby ensuring accurate inheritance of genetic material from one generation to the next. Missteps in the process can lead to cancer. Dr. Stillman is most widely known for his groundbreaking discovery of the Origin Recognition Complex (ORC), the initiator protein complex that is universal among eukaryotes. His subsequent research determined how the initiation of chromosome replication occurs and how it is regulated. He also highlighted other functions of ORC proteins in cells, including controlling gene transcription and the duplication of centrosomes, structures that orchestrate chromosome separation during mitosis. Mutations in ORC have been linked to Meier–Gorlin syndrome, a condition that results in people with extreme dwarfism.

Dr. Diffley:

The Work: Our very large genomes must be accurately replicated in each cell cycle, no part of the genome should be replicated more than once and replication must be completed before cell division. Using budding yeast as a model organism, Diffley has shown in molecular detail how DNA replication origins are regulated to ensure once per cell cycle replication. His laboratory has reconstituted the entire chromatin replication pathway using purified proteins. This has led to an understanding of how the replicative DNA helicase is loaded at origins, how it is activated, how it nucleates assembly of the replication machinery and how the replication machinery displaces and re-deposits nucleosomes during replication. He has also shown that DNA damage checkpoints regulate DNA replication on damaged DNA templates by inhibiting replication origin firing and promoting replication fork stability.

The Impact: Each time a cell divides, it must copy its DNA equally into two new cells. If the cell's DNA is not copied precisely before it divides, new cells end up without necessary genetic information which can prevent their division, lead to cell death, or cause many cells to divide out of control, forming a tumour.

By describing the exact sequence of events involved in DNA replication, Stillman and Diffley have provided key insights into how our genome is duplicated and how this process is coordinated with many other essential cellular events, which have implications for understanding genome instability and tumour heterogeneity in cancer.

2019 John Dirks Canada Gairdner Global Health Award
The 2019 John Dirks Canada Gairdner Global Health Award laureate is recognized for outstanding achievements in global health research:

Dr. Vikram Patel, Ph.D., FMedSci
The Pershing Square Professor of Global Health and Wellcome Trust Principal Research Fellow, Department of Global Health and Social Medicine, Harvard Medical School; Professor, Harvard TH Chan School of Public Health; Honorary Professor of Global Mental Health, Centre for Global Mental Health, London School of Hygiene & Tropical Medicine; Adjunct Professor, Centre for Chronic Conditions and Injuries, Public Health Foundation of India, New Delhi; Co-founder, Sangath, India

Awarded "For his world-leading research in global mental health, generating knowledge on the burden and determinants of mental health problems in low- and middle-income countries and pioneering approaches for the prevention and treatment of mental health in low-resource settings"

The Work: Dr. Patel has dedicated his research career to raising the global profile of mental health problems through: epidemiological research demonstrating the burden of mental disorders in low- and middle-income countries, their strong association with poverty and with other public health priorities, such as HIV and child growth and development; and intervention research in which he has applied a systematic approach to the design, delivery and evaluation of contextually appropriate psychosocial interventions provided by lay and community health providers. This has included the primary care treatment of depression, anxiety and alcohol use disorders, the community-based care of people with schizophrenia and autism, and the prevention and treatment of adolescent mental health problems through school-based interventions.

Much of his work has been done in partnership with Sangath, an Indian NGO he co-founded in 1996. Sangath is one of India's leading community-based research organizations which won the MacArthur Foundation International Prize for Creative & Effective Institutions in 2008 and the WHO Public Health Champion of India prize in 2016. Dr. Patel also co-founded the Centre for Global Mental Health and the Mental Health Innovations Network (at the London School of Hygiene & Tropical Medicine) and the Movement for Global Mental Health, the largest global network of individuals and organizations advocating for promoting services and human rights for people living with mental health problems. In 2018, he co-founded the GlobalMentalHealth@Harvard initiative which is developing a suite of innovative, inter-disciplinary, initiatives aimed at implementing and generating knowledge to transform mental health globally.

The Impact: As recently as 10 years ago, it was difficult to even imagine mental health problems being considered as a global health priority; today, the situation is radically different with considerable attention from a diverse range of global health stakeholders, backed by resources, being focused on mental health, particularly in disadvantaged and low resourced contexts. Patel's work and leadership has played a critical role in making this happen. His research has challenged many of the myths surrounding mental health problems in the global context, demonstrating that these problems are universal forms of human suffering; that there is a vicious cycle of deprivation and poor mental health; that mental health problems profoundly affect the physical health and well-being of affected persons; that psychosocial interventions can be effectively delivered by widely available and affordable community based providers; and that the human rights of people with mental health problems to access quality care and to a life with dignity are global concerns. This work and his leadership has made significant contributions to the establishment of the field of global mental health, with priority research, teaching, policy and practice agendas, for example the Grand Challenges in Global Mental Health research initiative, the World Health Organization's flagship mhGAP program on mental health and India's first national mental health policy.

2019 Canada Gairdner Wightman Award
The 2019 Canada Gairdner Wightman Award laureate is a Canadian scientist recognized for outstanding leadership in medicine and medical science throughout their career:

Dr. Connie Jean Eaves, Ph.D.
Distinguished Scientist, Terry Fox Laboratory, BC Cancer; Professor, Department of Medical Genetics, University of British Columbia, Vancouver, BC

Awarded "For her pioneering work and leadership in the study of hematopoietic, mammary and cancer stem cells and her dedicated advocacy for early- career investigators and women in science"

The Work: Dr. Eaves' research has focused on leukemia and breast cancer and the normal tissues in which these diseases originate. Eaves together with her husband, Allen Eaves, and a dedicated group of talented trainees developed methodologies to isolate putative stem cells from living mouse and human tissues, and detect them based on their ability to grow as single cells in specialized tissue cultures or in transplanted mice. This made it possible to quantify blood and mammary gland stem cells in different situations, and discover a hidden population of suppressed normal blood stem cells in patients with leukemia, which has stimulated a search for new therapies. Eaves also showed that leukemic stem cells are actually not dividing most of the time. Her studies of breast cells revealed that similar principles apply to understanding the normal growth of this tissue. More recently, she has developed new methods for creating human leukemia and breast cancer experimentally.

Throughout her distinguished career, Dr. Eaves has demonstrated outstanding national and international leadership. She co-founded the Terry Fox Laboratory at the British Columbia Cancer Agency, was a leader in the Canadian Stem Cell Network and held multiple senior roles in the National Cancer Institute of Canada, where she spearheaded the establishment of the Canadian Breast Cancer Research Alliance to create the first national source of breast cancer research funding in Canada.

In addition to the national and international accolades received throughout her career, Dr. Eaves is recognized for her exceptional commitment to the training of more than 100 scientists from around the world, including many now in senior leadership positions. Dr. Eaves is also a passionate advocate for the advancement of women in science, a commitment that led to her recognition as a Status of Women Canada Pioneer.

The Impact: Dr. Eaves has shown great initiative and immense talent across her five-decade career. Her dedication to multidisciplinary research and to providing the best training possible for aspiring researchers has strengthened Canadian science and garnered international recognition.

Eaves' scientific findings have been paradigm-shifting, driving the field of stem cell research forward. Her provision of reproducible and rigorously quantitative methods for analysing the rare cells responsible for maintaining normal blood and mammary tissues has enabled many new lines of research. Eaves continues to apply cutting-edge technology and elegant experimental design to the most pertinent problems in stem cell biology and cancer research, constantly contributing to the ongoing pursuit of cures.

QUOTES:

"On the 60^th anniversary of the Canada Gairdner Awards, the Gairdner Foundation continues to uphold the tradition of honouring the best and brightest researchers from around the world. Whether it is the field of global mental health, stem cell biology or fundamental cell biology and DNA replication, the work of each of this year's laureates is both critical and extraordinary," said Dr. Lorne Tyrrell, Chair, Board of Directors, Gairdner Foundation.

"2019 is an exciting year for the Gairdner Foundation. On the 60^th anniversary of the awards, Gairdner is proud to recognize another outstanding group of laureates. This fall, each of the 2019 Canada Gairdner Award laureates will participate in outreach programs across Canada to share their research and passion for science with graduate students, trainees, post-docs, faculty members and high school students," said Dr. Janet Rossant, President & Scientific Director, Gairdner Foundation. "I have no doubt that our 2019 laureates will help us to inspire the generation of scientists and researchers, and continue to raise the calibre of scientific conversation across the country."

About the Canada Gairdner Awards:

Each year seven Canada Gairdner Awards are presented to honour the world's most significant biomedical and global health researchers. The Canada Gairdner International Award is given to five individuals for outstanding international biomedical research, while the Canada Gairdner Wightman Award is given to an individual leader in Canadian medicine. The John Dirks Canada Gairdner Global Health Award recognizes a contribution to health in the developing world. These seven awards both distinguish Canada as a leader in science and elevate the profile of science in Canada. They are Canada's only globally known and respected international science awards. All laureates are chosen by international adjudication committees.

About the Gairdner Foundation:

The Gairdner Foundation was established in 1957 by Toronto stockbroker, James Gairdner to award annual prizes to scientists whose discoveries have had major impact on scientific progress and on human health. Since 1959 when the first awards were granted, 380 scientists have received a Canada Gairdner Award and 89 to date have gone on to receive the Nobel Prize.The Canada Gairdner Awards promote a stronger culture of research and innovation across the country through our Outreach Programs including lectures and research symposia. The programs bring current and past laureates to a minimum of 15 universities across Canada to speak with faculty, trainees and high school students to inspire the next generation of researchers. Annual research symposia and public lectures are organized across Canada to provide Canadians access to leading science through Gairdner's convening power.

SOURCE Gairdner Foundation

peopleCare Wins Innovation of the Year Award for the First Clinical Pharmacy Model in Canadian Long-Term Care

WATERLOO, ON, April 2, 2019 /CNW/ - With the complexity of care needs on the rise for Ontario's 68,000 long-term care residents, the need for an innovative approach to better manage their medications has never been more crucial. That's why peopleCare Communities and its partners developed a ground-breaking clinical pharmacy model, which has won a Quality Improvement Innovation Award from the Ontario Long Term Care Association (OLTCA).

"We are thrilled to receive this recognition from the long-term care sector for our leading practice Clinical Pharmacy Model," says Megan Allen-Lamb, President of peopleCare Communities. "The Award is an outstanding validation of our commitment to collaboratively drive innovation in the health system that directly improves the safety and quality of the care we provide to our residents."

A first of its kind in the Canadian long-term care environment, peopleCare's Clinical Pharmacy Model connects pharmacists directly with residents and staff, and leverages best-in-class software and automated dispensing cabinets. Research shows having an on-call pharmacist leading the medication reconciliation process supports higher quality decision-making and often results in fewer residents taking unnecessary medications, which is safer and more cost-effective.

The tele-pharmacy component of the model ensures expert medication reconciliation is available at any time, with full remote access to the electronic health record and medication lists. More efficient, this also enhances communication among the care team, particularly during transitions, when residents are more vulnerable to medication errors.

peopleCare and its partners – including Hogan Pharmacy Partners, eHealth Ontario, the LTC eConnect program, and PointClickCare – developed and piloted the Clinical Pharmacy Model in peopleCare's long-term care homes with the help of a $500,000 grant from the Ontario Healthcare Technologies Fund – the largest ever single grant awarded by the program.

Data from the pilot phase demonstrates the model's effectiveness at improving resident safety and supporting better clinical outcomes. Medication reconciliation improved by 43%. Staff documented a dramatic 8-hour decrease in the average time to first dose for residents newly admitted or re-admitted after a hospitalization. The new approach also freed up hundreds of hours of staff time that could be redirected to resident care.

According to Jenn Killing, peopleCare's Vice President of Quality and Innovation, over the past year peopleCare has worked proactively to share this trailblazing model with government, sector partners and experts, and plans to keep engaging with interested organizations in the coming months.

"All long-term care residents in Ontario would benefit significantly from this innovative solution," says Jenn. "We strongly encourage our health sector colleagues to connect with us to learn more about how they can leverage our Clinical Pharmacy Model to provide safer, more effective care for their residents. Our process, tools and lessons learned are an open book."

The OLTCA Quality Improvement Innovation of the Year Award is presented for a change idea, research project or collaboration with health care stakeholders, having achieved a positive impact on residents, staff or the home in early results. peopleCare's Clinical Pharmacy Model "Innovation of the Year" is showcased in the Spring/Summer 2019 issue of OLTCA's LONG-TERM CARE TODAY.

About peopleCare CommunitiespeopleCare Communities is a leading operator of senior living communities in southwestern Ontario, with strong family values and a long history of service. We are committed to creating vibrant communities of care that deliver clinical best practices, engaging programs and integrated services that meet seniors' changing needs. peopleCare's innovation and industry leadership has earned Accreditation Canada – Exemplary Status, Canada's Best Managed Companies designation for the sixth straight year, North America's Most Engaged Workplaces Award, and an Innovation Award research grant from the Health Technology Fund.

The World's First Affordable At-home Live Cell Collection Kit Now Available, Readying Everyone for the Future of Cell Therapy & Genetics

In-person collection experience debuts at MaRS Health Innovation Week; pre-order now open for innovative live cell home collection kit in Canada.

TORONTO, April 1, 2019 /CNW/ - Acorn Biolabs, a healthcare technology company focused on giving every human being the best chance to enjoy greater health as they age, has launched the world's first easy and affordable live cell collection, genetic analysis, and cryopreservation service through its non-invasive method of simply plucking a few hairs from your head.

With an introductory one-time collection fee of $299, Acorn will collect and cryopreserve your cells for future medical use. The one-time fee will include collection, a cell viability report, cell images, a report outlining your genetic age, as well as storage of your cells for your first year with Acorn. Annual cell storage fees as low as $99 for children under the age of 19 years old will be billed to clients who sign up for the service starting in their second year. Acorn is also making available a client referral program.

"Cell therapy is rapidly emerging as the future of healthcare," said Dr. Drew Taylor, Co-founder and CEO at Acorn Biolabs. "Your own cells are the key to leveraging its potential, increasingly unlocking preventative healthcare that can improve your healthspan. Medical advancements have allowed for doctors to use your own cells to predict, treat, and even eradicate disease and degenerative changes. Stem cell therapies, tissue engineering strategies, and regenerative medicine are all powered by using cells."

As cells age, they become increasingly damaged and less effective for use with cell therapy treatments. That's why consumers have already started to collect, preserve and store their cells as soon as possible — locking in their cells at their best. Unfortunately, existing methods of collecting live cells are highly invasive: from bone marrow extractions to liposuction surgery, and from venous blood draws to tissue harvesting. These procedures are painful and require medical teams, making live cell collection widely out of reach for most people.

To demonstrate how easy and accessible live cell collection can be, Acorn will debut its in-person live cell collection experience at a series of events across Canada this year including: MaRS Health Innovation Week, Total Health '19, Technology & The Future Of Healthcare 2019, Collision, BigData Toronto and Elevate, among others. At these events, consumers can personally experience Acorn's easy, non-invasive live cell collection service by having their own cells collected on-site.

Also starting today, Acorn has started taking pre-orders for its at-home live cell collection kit which is due to ship this year. The innovative kit design, supported by Acorn's non-invasive method, will allow consumers to collect their own live cells easily and non-invasively in the comfort of their homes by plucking their own hair follicles. Consumers can hold their place in line for the first run of kits by pre-ordering today at www.acorn.me.

Acorn demonstrated their unique capability today on stage at MaRS Health Innovation Week with a hair follicle collection demo where they plucked hairs of attendees in front of a live audience - safely collecting their cells for future medical use.

Today's popular saliva-based DNA home-collection kits are low cost cell collection alternatives, but only capture dead human cells, limiting their use. These DNA and ancestry tests currently focus on less than 1% of a full genome making it impossible to leverage those cells for anything other than ancestry and basic health reports.

Acorn's non-invasive method of plucking hair on your head allows for full genome collection, in addition to banking your live cells - all without traveling to a clinic or needing a physician or surgery, making live cell collection significantly more affordable and accessible for everyone.

Easily accessible, progressively more powerful. Your own cells are the next currency in healthcare.

About Acorn Biolabs, Inc.
Founded in 2017 by Steven ten Holder, Patrick Pumputis and Dr. Drew Taylor and born out of years of research, Acorn is a healthcare technology company. Based at Johnson & Johnson INNOVATION - JLABS in Toronto, in the MaRS Discovery District – the heart of innovation in medicine and biotechnology - Acorn is focused on giving every human being the best chance to experience more healthy years with its easy, affordable and non-invasive live cell collection, analysis and cryopreservation service. Acorn helps you save your cells today, to live a longer, healthier tomorrow. Visit acorn.me

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SOURCE Acorn Biolabs

Almost two thirds of Canadian men aged 18-34 don't know their testicular cancer risk

2019 Canada Gairdner Awards Recognize World-renowned Scientists for Transformative Contributions to Research that Impact Human Health

peopleCare Wins Innovation of the Year Award for the First Clinical Pharmacy Model in Canadian Long-Term Care

The World's First Affordable At-home Live Cell Collection Kit Now Available, Readying Everyone for the Future of Cell Therapy & Genetics

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