Genetic study of epilepsy points to potential new therapies

RCSI researchers play key role in international collaboration

DUBLIN, Dec. 10, 2018:  The largest study of its kind, led by international researchers including scientists at RCSI (Royal College of Surgeons in Ireland), has discovered 11 new genes associated with epilepsy.

The research is published in today’s issue of Nature Communications (DOI: 10.1038/s41467-018-07524-z). It greatly advances knowledge of the underlying biological causes of epilepsy and may inform the development of new treatments for the condition.

Researchers compared the DNA of more than 15,000 people with epilepsy to the DNA of 30,000 people without epilepsy. This has created a better understanding of genetic factors that contribute to the most common forms of this condition, and the results tripled the number of known genetic associations for epilepsy and implicated 11 new genes.

The researchers found that the majority of current anti-epileptic drugs directly target one or more of the associated genes and identified an additional 166 drugs that do the same. These drugs are promising new candidates for epilepsy therapy as they directly target the genetic basis of the disease.

“This work illustrates the power of scientists collaborating across countries and continents. Discovering these new genes for epilepsy provides important information towards novel treatments for the condition. This is another important step on the road towards curing the epilepsies,” said Gianpiero Cavalleri, Associate Professor at the RCSI Department of Molecular and Cellular Therapeutics and Deputy Director of the FutureNeuro SFI Research Centre.

"In addition to the biological insights provided by the findings, this study will encourage researchers to develop personalised and precision therapies for patients with difficult and complex epilepsy. This will provide better seizure control and will enable improved quality of life for patients and families," said consultant neurologist Norman Delanty, Associate Professor at RCSI, FutureNeuro and Beaumont Hospital.

“We have appreciated for some time that genetics plays an important role in epilepsy, however, until now, relatively little was known about the specific genes responsible for the most common forms of the disorder.  Identifying the genes that cause epilepsy is particularly important when we consider that a third of the 65 million patients worldwide will not become seizure free using current treatment options,” said Dr Colin Doherty, National Clinical Lead for Epilepsy and a Principal Investigator at the FutureNeuro Centre.

Over 150 researchers, based across Europe, Australia, Asia, South America and North America, carried out the research.  They worked together as part of the International League Against Epilepsy (ILAE) Consortium on Complex Epilepsies. The ILAE Consortium was formed by researchers in 2010, recognising that the complexity of genetic and environmental factors underlying epilepsy would require research across massive datasets, and therefore unprecedented collaboration on an international scale. Science Foundation Ireland (SFI) part-funded the study.

“Conducting a study of this size and scope is an incredible accomplishment that RCSI and FutureNeuro were delighted to help lead.  We look forward to building on the results of this study and strengthening international collaborations,” said Professor Cavalleri.

“The next steps would be expanding these results in an even larger sample, which is underway, and then drilling down on specific groups of patients and the genes that influence their type of epilepsy to trial new therapies,” Professor Sam Berkovic, University of Melbourne.

ENDS

About RCSI

RCSI is ranked among the top 250 (top 2%) of universities worldwide in the Times Higher Education World University Rankings (2019) and its research is ranked first in Ireland for citations. It is an international not-for-profit health sciences institution, with its headquarters in Dublin, focused on education and research to drive improvements in human health worldwide. RCSI has been awarded Athena Swan Bronze accreditation for positive gender practice in higher education.

About ILAE

The International League Against Epilepsy (ILAE) was founded in 1909 and is an organisation of more than 100 national chapters.

The goals of the ILAE are:

• To advance and disseminate knowledge about epilepsy
• To promote research, education and training
• To improve services and care for patients, especially by prevention, diagnosis and treatment

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Uncovering Our Natural Strengths To Live Up To Our Fullest Potential

Discovery Bay, CA, December 8, 2018—For everyone's holiday list this year, the gift that keeps on giving is The Gifted Journey: Five Transformative Steps to Uncovering Your Unique Path by Gallup-certified strengths coach Stephanie Moore. Moore's proven steps to finding our own path to living a more purposeful, joy-filled life are based on decades of personal experience in career development.

Moore stays focused on all things positive, as she introduces her actionable five-step process designed to help readers Discover, Discern, Dream, Design and Do what they were always meant to do based upon their natural strengths—their gifts.

Each of the five steps contains exploratory exercises that walk readers through personal reflection and the gathering of objective perspectives from trusted colleagues and friends. The result is a blend of self assessments and external input that makes The Gifted Journey uniquely adaptable to the needs of each individual.

Along the way, Moore shares professional and personal anecdotes to help drive home her impactful message that through embracing our authentic skill sets, we can move toward more promising futures with renewed passion and enthusiasm.

The Gifted Journey is for anyone questioning their direction in life, including those about to apply for colleges, those just starting out in their careers, downsizing statistics, or those who are simply unhappy with their current path and need some course correction. Each of these situations can be a powerful catalyst to seeking change, and the five steps in The Gifted Journey can help readers uncover their gifts and put them to work.

Stephanie Moore is a Gallup-certified strengths coach with more than two decades of experience in leadership development, career consulting and executive coaching. As a strengths-based practitioner, she has used her unique blend of expertise, passion and spirituality to help thousands of people discover more fulfilling and rewarding career paths. She has designed and currently delivers the highly successful and comprehensive development courses, Strengths-Based Development and Strengths-Based Teams, to organizations, universities and associations across the globe.

She launched The Moore Group, Inc., in 2000 and cofounded the nonprofit Catholic Strengths and Engagement Community in 2008. She is a native of Northern California and holds a bachelor's degree in psychology from St. Mary's College in Moraga, California. She is also a graduate of the School for Pastoral Ministry through the Diocese of Oakland. She is currently developing a series of retreats and workshops that follow The Gifted Journey process.

For more information, please visit www.thegiftedjourney.com.

The Gifted Journey: Five Transformative Steps to Uncovering Your Unique Path
Inspired Forever Book Publishing
Released: September 2018
ISBN-13: 9780999625880
ISBN-13: 9780999625897
Available from Amazon.com and other e-book retailers

Reviews:

Fredrick Gilbert, Ph.D., Let'er Rip Productions – "… Whether you are starting out life in high school or making major mid-life changes this book is the tool belt that will help you construct your future. It is all here: self-assessment tools; exercises to understand your strengths and passions; ways to evaluate where you fit into the world of work. Stephanie's writing style is so accessible. She feels like an old friend who is being straight with you by letting you inside her own life-changing struggles. … If you are struggling to understand how your past can chart your future happiness, read this book. Do the exercises. Put it into action. Then write a thank you note to Stephanie.”

Mary McGlynn, president and VP of learning, development and research, PowerSpeaking, Inc. – "Stephanie Moore's The Gifted Journey serves as your personal archaeologist. As you proactively become a searcher of clues, a seeker of patterns, and a creator for your own fulfilled future, you find the path to your own career satisfaction. With assessments, tools, and exercises, your story unfolds in a magical way.”

Jo Ann Miller, OSF Strengths Development Center, former 40-year Gallup employee – "The Gifted Journey, is an amazing contribution! As Stephanie shares from her own gifted journey, she will lead you to discover your own 'conscious competence' at whatever time in your life you meet her invitation. When individuals truly work in their 'strengths zone,' it feels 'just right to them and others like it too.' One can feel Stephanie's joy and pleasure—not only in her own life's multifaceted talent discoveries, but in her day-to-day experience of living them out. Walk with Stephanie through her 5-D strategy for life's journey. Find a GIFT on every page as you 'learn, love and live' your gifted journey.”

Rick Fersch, former president and CEO of Eddie Bauer – "The 'WOW' moment in this book is when you recognize that each day is a gift waiting to be opened and discovered. I strongly subscribe to Stephanie's thesis that our life journey should be used to uncover and emphasize our strengths—and to build upon these gifts for a more fulfilling and promising future. Executing this 5 stage process will allow us to live the life that was always intended just for us. I was a business leader for over 30 years, and as president and CEO of Eddie Bauer, I suffered a life threatening stroke that changed my world and led me to embrace these stages. Using this process allowed me to discern how best to change my course, and how to apply my gifts to the faith world as Executive Director of Stewardship and Development at the Archdiocese of Seattle. Through living my own life journey, I can readily embrace and endorse Stephanie's well laid out process. It is both refreshing and innovative—building on widely known and successful concepts for helping to find your true self. Her unique and easy to read format allows you to execute action points that help support your master life plan.”

Rock Solid Research On How To Prevent Dementia And Maintain A Healthy Brain

Chattanooga, TN, Dec. 7, 2018 ― Dr. Timothy R. Jennings speaks expertly on a subject that concerns over 5.5 million people across the nation: how to prevent dementia and keep our mind sharp as we age. A psychiatrist and international speaker, Jennings introduces his new book, recently rated #1 by Amazon in books on dementia, The Aging Brain: Proven Steps to Prevent Dementia and Sharpen Your Mind.

Dr. Jennings prescribes simple, everyday actions we can take to stave off disease, promote vitality, and prevent dementia and late-onset Alzheimer's. "The choices we make now can help us to keep our minds sharp and maintain our independence as we age,” says Jennings.

An easy-to-use guide to maintaining brain and body health throughout life, The Aging Brain is based on solid, up-to-date scientific research, and the interventions discussed can prevent progression toward dementia, even in those already showing signs of mild cognitive impairment. The recommendations also may help reduce disability and depression.

"This book isn't just for people hoping to slow the aging process,” says Jennings. "It's also for anyone who is a caregiver to someone at risk of or already beginning to suffer from dementia. It offers a hopeful, healthy way forward.”

Jennings, who maintains a private practice in Chattanooga, TN, has authored several books, including The God-Shaped Brain and The God-Shaped Heart. He is a Distinguished Fellow of the American Psychiatric Association and Fellow of the Southern Psychiatric Association, and is president and founder of Come and Reason Ministries.

For more information about Dr. Jennings, please visit the website: https://www.agingbrainbook.com.

To connect with Dr. Jennings, please visit: https://www.facebook.com/DrTimJennings/ and https://twitter.com/timjenningsmd.

The Aging Brain: Proven Steps to Prevent Dementia and Sharpen Your Mind
Baker Books
Released: June 2018
ISBN-10: 080107522X
ISBN-13: 978-0801075223

###

Reviews for The Aging Brain: Proven Steps to Prevent Dementia and Sharpen Your Mind:

Dr. Caroline Leaf, Cognitive Neuroscientist, Communication Pathologist and Author: "Great advice and excellent science on aging! It's well worth following and applying these principles so as to age the way we are supposed to.”

Rodney A. Poling, MD, DFAPA, medical director, Behavioral Healthcare Center, Columbia TN., and board-certified geriatric psychiatrist: "A well-researched and commonsense book aimed at helping one understand the complexities of dementia, while offering recommendations for maintaining healthy brain function into our later years.”

Michael Lyles, psychiatrist, author, and speaker: "Dr. Jennings clearly describes how to practically manage the medical and lifestyle variables that can positively impact brain health and the process of aging. Age is a number, but getting old is a lifestyle.”

Sweat it Out: How to Increase Fat Loss during Your Workout

If you have been exercising for any length of time, you know how good regular movement is for your body. It can keep you feeling limber, give you more energy, improve your mood and lower your risk of many chronic health conditions. However, if you want to ensure that your workouts are specifically targeting extra fat that you have, try these four smart workout tips.

Try Strength Training

Muscle burns more calories than other tissues do. Therefore, it is in your best interest to focus plenty of your workout time on strength training each week. You can try using light weights with high reps, or you can choose to use very heavy weights to max yourself out in under eight reps. Both types of strength training can help you get lean without bulking up dramatically.

Try High Intensity Interval Training

High intensity interval training, or HIIT workouts, have been gaining in popularity over the past few years. Not only are they a fun new way to spice up your workout, but also they have been shown to be better at burning calories and fat off your body in a shorter amount of time than you would see with regular cardio. Try working out at your highest intensity for two minutes before leveling off for the third minute. Do this over and over throughout your workout time.

Try More Cardio Exercise Overall

Despite the benefits of HIIT workouts, it is still important for you to get in your regular cardio workouts as well. After every cardio workout, you continue to burn fat calories at an increased rate for several hours. You will notice that your metabolism is boosted. Therefore, it is important to raise your heart rate regularly several times every week. Even in cold weather, you can continue your outdoor cardio workouts when you wear warm running leggings and long sleeve performance shirts.

Exercise Hungry

Although this may initially make you feel quite uncomfortable, you can ensure that your body is using fat stores for energy if you exercise on an empty stomach. This is especially effective in the morning when you are sure that your body has burned through all of its food from the prior night. Go for a run or do your cardio workout first thing in the morning before having a protein-packed breakfast to get you ready for the rest of the day.

While anyone knows that weight loss occurs when you burn more calories than you take in, it is not always that easy to focus on fat loss, especially if you want to keep up your muscle mass. However, by focusing on smart strength training, using HIIT workouts frequently, amping up your cardio workouts, and knowing when to eat around your workout time, you can ensure that your body is working its hardest to burn through your unwanted fat stores. Slowly start integrating these changes into your regular workouts, and watch your body become lean and strong.

Disability leave due to mental health issues can be avoided

5 Things You Need to Kow About Probiotics

By Eddie Fatakhov M.D. (a.k.a. Dr. Fat-Off)

What is a probiotic?

Probiotics are not only live microorganisms found in supplements and some fermented foods such as yogurt and pickles, they have also been found to have a variety of health benefits. These benefits include vitamin K and B production, the breakdown of insoluble (indigestible) fiber, immune system support, the improvement of mental health, improvement of heart health, reduction of certain allergies and skin conditions, and (possibly one of the most sought after effects) the reduction of belly fat.

What is the link between probiotics and body fat?

There are large populated families of primarily friendly microorganisms (bacteria) living in your digestive system, two of which are families tied to the management of body fat – bacteroidetes and firmicutes. According to a wide variety of studies, body weight is related to the balance of these two families of bacteria.

These studies look at the difference between the gut bacteria in normal-weight people versus overweight or obese people. The major difference found was that obese subjects had an imbalance in their firmicute levels versus their bacteroidetes.

Which probiotics help you lose weight?

Not all probiotics are created equal. While there are many strains available, only a few have been proven to have positive effects on weight. One strain that studies have found to assist in weight loss is the Lactobacillus family. Studies have found the following to be true:

• When paired with diet and exercise eating yogurt with Lactobacillus fermentum or Lactobacillus amylovorus helped to reduce body fat by 3–4% over a 6-week period.
• The effect of Lactobacillus rhamnosus supplements was measured on 125 subjects for weight loss and weight maintenance. The study found women taking the probiotics over a three month period lost 50% more weight than the placebo group.
• Lactobacillus gasseri is one of the most productive probiotic when it comes to weight loss. This specific probiotic inhibits dietary fat absorption. This means the calories your body would otherwise “harvest” are excreted instead.

How can probiotics help you lose weight?

While research is still ongoing, here are some of the ways probiotics are thought to assist in weight loss:

• They release GLP-1. Probiotics may play a part in the release of GLP-1 (appetite-reducing hormone). Studies have shown increased levels of GLP-1 may actually help you burn calories and fat.
• They increase production of ANGPTL4. Levels of the protein ANGPTL4 may rise from probiotic use. This production might actually lead to decreased fat storage.

Are probiotics safe?

There are many types of probiotics available today. Because of this it’s good to remember that some have a lot research behind them and some do not. Here are somethings to know before you buy a probiotic:

• Mild side effects are possible such as gas or bloating within the first few days of use.
• All foods with probiotics are not created equal.
  While these foods usually have good levels of live bacteria – “live and active cultures” yogurt, kefir, aged cheeses, brined pickles, sauerkraut, tempeh, and miso – products that claim to have probiotic benefits might not. Enriched juices, cereals, and snack bars may have less than promised levels, or weakened forms of the organisms.
• Probiotics might not be safe for everyone.
  People with weakened immune systems, such as cancer patients in treatment, should avoid probiotics.
• Expiration dates and storage are very important.
  Because probiotics are living organisms they have a limited shelf life. Using probiotics before their expiration dates and following the suggested storing advised on the product label maximizes their potency.

Before taking any supplements we recommend talking to your doctor to ensure you are taking one that is right for you.

If you would like more information on probiotics, please contact The Center for Internal and Integrative Medicine 

ABOUT DR. FAT-OFF…

Eddie Fatakhov, M.D., a.k.a. Dr. Fat-off, is a Board-Certified Physician, Nutritionist, and Best-Selling Author of "The Doctors' Clinic-30 Program. His latest book is “Dr. Fat-Off Simple Life-Long Weight-Loss Solutions.”

Email: eddie@drfatakhov.com

Office: 404-836-9906
Website: www.eddiefatakhovmd.com
Facebook: https://www.facebook.com/fatakhov

Instagram: http://instagram.com/eddiefatakhovmd/

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7 Ways to Boost Energy Without an Energy Drink

By Dr. Niket Sonpal NYC Internist and Gastroenterologist

https://tourocom.touro.edu/academics/faculty/harlem/niket-sonpal.php

After seeing the news about a research study out of the University of Texas Health Center in Houston, which found the diameter of blood vessels to become “dramatically smaller” 90 minutes after consuming a 24-ounce energy drink, I decided to offer some ways to boost energy without an energy drink.

While the 24-ounces used in the study of 44 healthy, non-smokers in their 20’s, is 3 times the size of a typical 8-ounce energy drink, there is plenty of research out there that shows chugging energy drinks is not the best way to get more energized.

When we look at the levels of sugar and caffeine in these energy drinks and the habitual nature in which they are consumed, we see issues such as increased heart rate, elevated blood pressure, thickening of the blood, gastrointestinal irritation plus anxiety, sleep disruption and restlessness.

Here’s what I suggest consuming for a more sustainable and healthy way to energize.

1. Hydrate with water. The idea is to follow the 8x8 rule. Eight ounces of water 8 times per day which adds up to a half gallon. Most people are not getting anywhere near this water intake opting for coffee, juices, sodas or energy drinks instead. I challenge my patients to try the 8x8 rule and even declare going “H20 Only.” By the third day, they notice they’re feeling more energized.

2. Exercise 30 minutes per day.

Something as simple as going for a fast-paced walk elevates heart rate and healthy blood flow. This improves stamina and gets energy flowing throughout our bodies. A lot of people claim they don’t have time to exercise which calls for creative ways to get exercise in. I had a client add dancing for 30 minutes upon her arrival from work with her 4-year-old daughter. This provided a way for both mom and daughter to get moving in a fun easy way right at home.

3. Sprinkle in chia seeds.

These low carb seeds have an energy packing blend of protein, fats, and fiber. Chia seeds regulate blood sugar, so you won’t have these spikes then drops. They deliver big time nutrients with very low calories. Loaded with antioxidants, chia seeds were a highly valuable energy staple for Mayan and Aztec warriors in ancient Mexico who consumed them knowing they would be sustained, not hungry and energized for hours and hours.

4. Eat foods rich in Omega 3 Fatty Acids.

Omega 3’s are big-time energy enhancers. Eating salmon, sea bass, tuna, oysters, shrimp, seaweed salad, walnuts, edamame, and cauliflower are just a few Omega 3 rich staples to add to the shopping list.

5. Get good quality sleep.

Many of my patients who see me for gastrointestinal issues often benefit from getting disciplined with setting a bedtime, wake time and enhancing the quality of their sleep. This could be simple things such as pre-sleep meditation with an app, removing the television from the bedroom, buying curtains that block light, setting the temperature to suit your body best, buying new sheets and even a new mattress.

Making the bedroom a comfortable haven for quality deep sleep is incredibly important. Sleep is our time to recharge and when it is disturbed, we will feel sluggish during the day.

6. Get more magnesium.

Magnesium activates adenosine triphosphate (ATP) which can be thought of like the “magic button” of energy within our cells. According to studies, about half of the people in the USA and Europe aren’t getting the recommended amount of magnesium (300 milligrams for women and 350 for men).

Interestingly, most Americans and Europeans complain of energy drains and sluggishness and typically attribute their lack of energy to busier, more demanding lifestyles. However, the problem, most commonly, is a lack of magnesium which helps us convert food into energy, create proteins from amino acids, and helps regulate our nervous system.

7. Get more B12.

Known as the “energy vitamin” it’s important to note that the only time B12 will give you energy is if you’re deficient in B12. It’s wise to get complete blood work done to see if you are in fact deficient in B12 in addition to other key vitamins and minerals.B12 is found in beef, fish, and dairy and these days more and more people are cutting red meat and dairy out of their diets.

B12 helps to make red blood cells, which carry oxygen, so when there’s a dip in red blood cell production we’re being deprived oxygen which leads to feeling run down, the first tell-tale sign of B12 deficiency. Body weakness, shortness of breath brain fog, forgetfulness and lack of focus are also symptoms. Yogurt, Swizz cheese, fortified cereals, Shiitake mushrooms, and clams are other great sources of B12.

About Dr. Niket Sonpal:

Dr. Niket Sonpal is an Adjunct Assistant Professor at Touro College of Osteopathic Medicine and Clinical instructor at Kingsbrook Jewish Medical Center, Brooklyn who specializes in Gastroenterology. He is a graduate of the Medical University of Silesia – Hope Medical Institute in Poland. After completing his residency in Internal Medicine at Lenox Hill Hospital, he was selected to be the 2013‐2014 Chief Resident at Lenox Hill Hospital–Northshore LIJ Health System. Dr. Sonpal has completed his Fellowship in Gastroenterology & Hepatology at Lenox Hill Hospital and continues his work in the field of medical student and resident test preparation. He now serves as the associate program director for the Internal Medicine Residency Program at Brookdale University medical center.

He is the co‐author for the best-selling Master the Boards: USMLE Step 2 CK, Master the Boards Step 3, And Master the Boards: Internal Medicine. He is also the Chief Operating Officer for Medquest Test Prep, Director of Medical Education for Picmonic Test Prep, and a recognized expert on medical test prep.

This article, 7 Ways to Boost Energy Without an Energy Drink appeared first on KMRPR.

One Woman's Mission To 'Quiet The Anger' And Reduce Stress As We Approach The New Year

Charlotte, NC, December 6, 2018 ― Charlotte pastor and face of the popular Car Chronicles Movement, Jameliah Young-Mitchell has penned The Death of the Angry Black Woman—a book published by Warren Publishing that discusses stereotypes faced by African-American women. The book released at #1 on Amazon.com for New Releases in the Anger Management category.

Anger can get the best of many women, but when anger erupts into rage and leads to shouting, fighting, and name-calling, it's time to look within and make a change. The Death of the Angry Black Woman boldly acknowledges stereotypes faced by women in the black community and uncovers the seeds that lead many to live anger-filled lives. Instilled with Biblical scripture and jaw-dropping honesty, this debut book from Pastor Jameliah Young-Mitchell, the voice behind the popular Car Chronicles Movement, will empower you to bury your anger, reject false labels, and embrace the new you.

"I wrote this book for all the women out there who are dealing with anger that they have yet to find the source of,” said Young-Mitchell. "Many women in the black community come from backgrounds of abuse, mistreatment, violence––and they become fighters. Through my book I hope to be that voice in their head, the one we all hear but rarely acknowledge, encouraging them to move on, let go of anger, reject hateful labels, embrace their powerful femininity, and live the life God intended them to live.”

Pastor Jameliah Young-Mitchell is the daughter of the late Evangelist Violetta B. Young and Pastor James I. Young, and grew up in Brooklyn, NY, as the youngest of four kids. She has preached across the United States and internationally and is the pastor of Unity Church Charlotte. Young-Mitchell is an experienced keynote speaker for women's empowerment, teen and youth mentoring, corporate America, and relationships. She is the voice behind the popular Car Chronicles Movement where she can be seen live on Facebook Monday through Friday at 7:30 a.m. Young-Mitchell is the proud mother of a son and daughter and resides in Charlotte, NC, with her husband, Calvin W. Mitchell.

The Death of the Angry Black Woman is available at warrenpublishing.net, Amazon.com, or wherever books are sold. Jameliah Young-Mitchell is available for book signings and interviews.

The Death of the Angry Black Woman
978-1943258-92-5
Released: 2018
Soft Cover
$15.00

Select excerpts from many five-star reviews on Amazon.com:

"This book is an awesome read! The transparency and life examples of Pastor Jameliah Young- Mitchell gives [sic] the reader a firsthand view of what an overcomer looks like. There is something for everyone to learn and apply to their lives to become better people.”

"At first I wasn't interested in reading this book because I felt that I was not 'Angry' but as I read I discovered that I was angry and suffered some of the same things but learned how to mask the pain. This book allowed me to begin the process of a new me. I highly recommend this book to anyone that is in need of refocusing.”

"I recently joined a book club with a few other ladies and this was one of the first books recommended. I could relate to a lot of the content in the book and was able to dig a little deeper and have a little self-reflection afterwards. I highly recommend this!”

"I liked everything about the book. From the start to the end... it's a mind-blowing moment for real I tell you! This is a 10-star book.”

"This book is just awesome. It has definitely set me free, it has been a blessing to My Mind & Soul.”

"[Jameliah] is very candid in this book. She has a way of leading, teaching, and encouraging, all while openly acknowledging that she too is still learning. It is written in such a way that EVERYBODY can understand. I love it!!”