TimiHealthProgram Empowering Consumers to Profit from their DNA Data Will Be Listed on LATOKEN Where Trading Starts Aug. 9, Part of a Two Million Timicoin Giveaway

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AUSTIN, TX. – Aug 8, 2018 – Timicoin/TimiHealth(www.timicoin.io),the first operating blockchain designed to empower individuals through itsTimiDNA platform to own, control, and monetize their genetic DNA data,will also be the first to actually pay them for it via LATOKEN (www.LATOKEN.COM).

On August 20, 2018,TimiHealthwill be launching the TimiDNA platform on LATOKEN and theTwo Million Timicoin Giveaway!at the Blockshow (https://blockshow.com/) in Las Vegas. The first 100,000 individuals who upload their DNA data to the TimiDNA platform will receive 20 Timicoins.

“Instead of the current model where consumers are paying for the privilege for others to profit from their DNA, we at TimiHealth will be the first to pay consumers for the honor to secure their DNA in our proprietary TimiDNA distributed blockchain. We want to pay individualsa similar amount to what GSK paid 23andMe for their data, and to also empower them as consumers to tokenize and continue to profit from the genetic data that truly belongs to them,” said Joyce Lignell, Chairwoman ofTimiHealth’sAdvisory Board.

The recent announcement that GlaxoSmithKline (GSK) is investing $300M in 23andMe to access the genetic DNA data of five million consumers for pharmaceutical drug development, with a 50/50 split on future profits, exemplifies the fact that the very consumers who are sourcing that DNA data are being left out in the cold (https://www.gsk.com/en-gb/media/press-releases/gsk-and-23andme-sign-agreement-to-leverage-genetic-insights-for-the-development-of-novel-medicines/).GSK paid a transactional value of approximately $60 per consumer to simply to access their data, with a tremendous future upside for the development of blockbuster drugs that potentially could be developed, none of which the consumer will see a dime.

“We know how truly valuable genetic and DNA data is to the future of medicineand believe that consumers who choose to share or sell their data should receive the lion’s share of the financial windfall that comes from it. TimiHealth is on a mission to tokenize consumers’ DNA information and allow them to first compile their data in a highly secure, distributed TimiDNAblockchain, while also giving them the ability to sell or refuse to sell that data to researchers. We are opening the eyes of consumers to the fact that genetics companies are cutting deals with big pharma for tremendous amounts of money that should belong to the people that are the very source of the data,” said Timicoin/TimiHealth’s, founder Will Lowe.

 

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Compelling Bestseller Helps Families Of Missing Children Cope With Unspeakable Grief

Houston, TX, August 8, 2018 ― Four years ago, Marie White's youngest child was abducted, and in that instant, White's family became one of a frightening statistic.

Over two million families in the United States have faced the unthinkable grief of losing a child through divorce, alienation, abduction, human trafficking or drug addiction. Some of those affected by such profound loss break down mentally, suffer from PTSD, become pathologically depressed, or turn to drugs and alcohol. Some even end their suffering through suicide.

White used the pain of her experience to reach out to others who are desperate for answers while their child is gone.

Her compelling book, Strength for Parents of Missing Children: Surviving Divorce, Abduction, Runaways and Foster Care, is a real, how-to guide for surviving the worst case scenario and finding joy and deeper purpose in the midst of pain.

The book features insights from renowned experts, including Dr. Sue Cornbluth, a nationally recognized expert in parenting and childhood trauma; Logan Clarke, one of the top investigators in the world; and Dr. Raymond Mitsch, psychologist and author of the bestselling book, Grieving the Loss of Someone You Love.

Peppered with reflections on her own personal experiences, White fearlessly covers topics like depression, PTSD, reunification and grief in a way that is both informational and inspirational. Woven throughout are Bible verses meant to strengthen, encourage and motivate families of missing children to find hope through their faith in God.

Strength for Parents of Missing Children is a raw, honest account written by a parent who has not only lived it, but is still living it and still managing to thrive in the midst of grief.

In addition to Strength for Parents of Missing Children, author Marie White has written six other books, including Ten Day Bible Study: Standing Firm on God's Word (Zamiz Press, 2017) and Changing Your Life in Just 10 Days: Creating the Life You Were Always Meant to Live (Zamiz Press, 2016). She is also a TEDx speaker, non-denominational Christian missionary, traveler, entrepreneur and reaches over half a million viewers through her YouTube channel, Bible Stories for Adults. She owns Zamiz Press (Za-h meez), a book publishing company.

To learn more, please visit www.MarieWhiteAuthor.com.

Strength for Parents of Missing Children: Surviving Divorce, Abduction, Runaways and Foster Care
Hawaii Way Publishing
ISBN-10: 1945384093
ISBN-13: 978-1945384097
Available everywhere books are sold

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TIP SHEET:

Suggested interview questions for Marie White:

1. When we think of missing children, we think of kidnapping or abduction. But you say there are other types of missing children. What are these other types?
2. What are parents of missing children going through physically?
3. What are the emotions that parents go through?
4. What can friends and family say to help hurting parents?
5. What are some things people should not say?
6. What three things can you tell parents living through this right now?
7. You're a veteran. How has your military training influenced how you handle this?
8. How has going through this impacted the way you look at life?

Reviews:

Rev. Daniel B. Gilbert, Ph.D., EmPowered Living International Ministries: "Reading this book is a must for all parents, whether a tragedy has happened or not! As a minister and professor, this book has helped me understand the grieving process even more so I can help others. Marie White writes with such compassion from her heart, yet not withholding the truth that individuals and parents must deal with during loss. I highly recommend Marie's book and hope it will help you as it has helped me.”

Marcy Pusey: "I'll start with noting that I am a clinical counselor. While this book is about families of abducted children, I found SO much value for ANYONE who has experienced loss or grief. The author does a great job communicating practical ways of surviving that trauma. I know anyone walking this living tragedy will find strength and companionship on these pages.”

L. Aiello: "As a parent of an alienated child, I appreciated having this situation profiled alongside other serious losses of children. Finding hope and inspiration to carry on is a real challenge when you are separated from your child, no matter what the reason. Marie's book supports parents in all situations where they are struggling with not knowing and not being with their children. Her book is truly a warm blanket on a very cold night!”

Marcie L. Humphrey: "I highly recommend this book to anyone who is going through parental alienation or any other type of parental loss."

Ontario's Organ and Tissue Donor Registry Tops Four Million

 

TORONTO, Aug. 7, 2018 /CNW/ - Trillium Gift of Life Network, Ontario's government agency responsible for organ and tissue donation and transplantation, announced a milestone today: four million Ontarians have registered consent to donation.

Ontario reached this achievement fittingly during BeADonor Month in April – a month devoted to celebrating and raising awareness for organ and tissue donation.

This past BeADonor Month was incredibly successful, with a 24 per cent increase in new registrations over an average month in 2017. In large part, this was owing to Ontario's overwhelming response to the Humboldt tragedy and Logan Boulet's lifesaving gift. Moved and inspired by his generous act, thousands of Ontarians became registered donors.

"Although we should be proud of our nation's outpouring of support, it should not take a tragedy to jolt people out of their complacency," said Ronnie Gavsie, President and CEO. "Every three days in Ontario we face a tragedy when someone on the waitlist dies because there are not enough organs to meet the need."

Registration is vital

Donor registration has been proven to save lives. Families overwhelming honour their loved ones' decision to donate organs and tissue at end of life, when they are registered. In the absence of registration, families consent to organ donation only half of the time.

"Through organ donor registration, Ontarians are saving lives. Also, registration relieves families of the burden of making a decision to donate organs and tissue on their loved ones behalf during an already difficult time," said Gavsie.

Partnering to save lives

This milestone is also a testament to the strong partnership between Trillium Gift of Life Network and ServiceOntario. Ontarians are offered the opportunity to register consent to donate when renewing a health card or driver's licence. This interaction is fundamental to the donation system because being asked by front-line staff to register consent accounts for 90 per cent of new donor registrations.

Culture of donation

While the vast majority of Ontarians support organ and tissue donation, only one in three have registered their consent to donate.

"Reaching four million registered donors is a momentous breakthrough and something we have worked very hard to achieve, so we certainly want to celebrate this achievement. However, a true culture of donation in the province can only be claimed when the majority of Ontarians are registered," said Gavsie.

Northern Ontario has set the bar with 49 per cent of the eligible population registered. Top-ranked communities include North Bay (56 per cent), Parry Sound (55 per cent) and Sudbury (54 per cent). Central Ontario, including Toronto (23 per cent), Mississauga (21 per cent) and Brampton (18 per cent), falls below the provincial average with only 25 per cent registered.

Ontarians are encouraged to join the four million individuals already registered for organ and tissue donation by visiting www.BeADonor.ca to register or learn more. Registration rates by community are available at www.BeADonor.ca/scoreboard.

Trillium Gift of Life Network is a not-for-profit agency of the Government of Ontario responsible for planning, promoting, coordinating and supporting organ and tissue donation for transplantation across Ontario and improving the system so that more lives can be saved.

SOURCE Trillium Gift of Life Network

ProMIS Neurosciences Issues Narrated Commentary on Key Learnings from AAIC 2018

 

TSX: PMN; OTCQB: ARFXF

Encouraging results of recent clinical trials in Alzheimer's disease indicate importance of selectively targeting toxic amyloid-beta oligomers

TORONTO and CAMBRIDGE, MA, Aug. 7, 2018 /CNW/ - ProMIS Neurosciences, Inc. (TSX: PMN; OTCQB: ARFXF), a biotechnology company focused on the discovery and development of antibody therapeutics targeting toxic oligomers implicated in the development of neurodegenerative diseases, today announced it has issued a narrated commentary on key lessons from this year's Alzheimer's Association International Conference (AAIC).

Results of prior and current clinical trials with therapeutics targeting amyloid-beta (Aß), including encouraging Phase 2 results of Esai/Biogen's Ban2401 presented at AAIC, indicate that selective targeting of toxic amyloid-beta oligomers (AßO) is critical for therapeutic efficacy. The importance of neutralizing AßO toxicity represented a common theme across multiple oral presentations and posters at this year's AAIC.

"A growing body of evidence indicates that AßO, consisting of small aggregates of two, four or twelve Aß peptides are the toxic oligomers killing neurons in Alzheimer's disease. Numerous scientific studies have shown that other forms of amyloid-beta, plaque, single Aß monomers, and large Aß aggregates are not toxic to neurons.", stated Dr. Elliot Goldstein, ProMIS President and CEO.
"Our humanized PMN310 antibody shows unrivaled selectivity for toxic AßO derived from human AD brains, with no off-target binding to Aß monomers or plaque. We believe the oligomer selectivity of PMN310 supports a potential best in class product profile compared to other therapeutic antibodies currently showing promising results in clinical trials."

ProMIS' clinical candidate, humanized PMN310, is on track to enter Phase 1 clinical testing in the second half of 2019 and will include biomarker assessment as an integral part of the study design.

ProMIS narrated commentary can be found on the ProMIS Neurosciences website by clicking on the link below:
https://bit.ly/2OgyYlH

About ProMIS Neurosciences, Inc.

ProMIS Neurosciences is a development stage biotechnology company focused on discovering and developing antibody therapeutics targeting toxic oligomers implicated in the development and progression of neurodegenerative diseases, in particular Alzheimer's disease (AD), amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD). The Company's proprietary target discovery engine is based on the use of two complementary techniques. The Company applies its thermodynamic, computational discovery platform—ProMIS™ and Collective Coordinates — to predict novel targets known as Disease Specific Epitopes (DSEs) on the molecular surface of misfolded proteins. Using this unique precision medicine approach, the Company is developing novel antibody therapeutics for AD, ALS and PD.  ProMIS is headquartered in Toronto, Ontario, with offices in Cambridge, Massachusetts. ProMIS is listed on the Toronto Stock Exchange under the symbol PMN, and on the OTCQB Venture Market under the symbol ARFXF.
For further information please consult the Company's website at:  www.promisneurosciences.com

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Neither the TSX nor its Regulation Services Provider (as that term is defined in the policies of the TSX) accepts responsibility for the adequacy or accuracy of this release.  This news release contains certain "forward-looking statements" within the meaning of Canadian securities legislation. Forward-looking statements are statements that are not historical facts; they are generally, but not always, identified by the words "expects", "plans", "anticipates",  believes", "intends", "estimates", "projects", "aims", "potential", "goal", "objective", "prospective", and similar expressions, or that events or conditions "will", "would", "may", "can", "could" or "should" occur. Forward-looking statements are based on the beliefs, estimates and opinions of the Company's management on the date the statements are made and they involve a number of risks and uncertainties. Consequently, there can be no assurances that such statements will prove to be accurate and actual results and future events could differ materially from those anticipated in such statements. Except as required by the securities disclosure laws and regulations applicable to the Company, the Company undertakes no obligation to update these forward-looking statements if management's beliefs, estimates or opinions, or other factors, should change.

SOURCE ProMIS Neurosciences Inc.

TimiCoin/TimiHealth Empowers Consumers to Retake Control of Their Genetic DNA Data


NEWS PROVIDED BY

TimiCoin/TimiHealth 

 


AUSTIN, Texas, Aug. 7, 2018 /PRNewswire/ -- Timicoin/TimiHealth, the first operating blockchain designed to empower every individual through the TimiDNA platform allows you to own, control, and monetize your genetic DNA data.

TimiHealth has developed the intellectual property that will protect individuals as they upload their data to the decentralized platform delivering on its trademark branding as the leader in "Tokenized Healthcare™."

There is no doubt that concerns about health care data-- particularly its security and privacy—have been escalating in recent years, said Will Lowe, founder and Managing Partner, Timicoin/TimiHealth.

The recent announcement that GlaxoSmithKline (GSK) is investing $300M in 23andMe to partner on leveraging genetic DNA data for pharmaceutical drug development with a 50/50 split on future profits further highlights the need for consumer ownership of their own data (https://www.gsk.com/en-gb/media/press-releases/gsk-and-23andme-sign-agreement-to-leverage-genetic-insights-for-the-development-of-novel-medicines/).

While we all support the development of beneficial, perhaps even disease-curing drugs, the subterfuge surrounding the use of people's personal health and genetic data is deeply concerning, said Lowe.

Millions of people pay companies like 23andMe, Ancestry.com, and Helix substantial fees to obtain information regarding their heritage, genetic disposition for certain disease states, or pharmacologic compatibility with drug regimens.  Unfortunately, most consumers are unaware that the personal data gleaned from such tests can then be sold to any number of research organizations for huge profits—none of which are realized by the consumers themselves.

"TimiHealth and its TimiDNA platform is driven by a mission to remedy these inequities by enabling consumers to own, control, and secure the totality of their health data, including that about their genetic DNA. TimiHealth is built on the principles of trust, transparency and empowerment, with a goal of putting control back into the hands of the true owners of this valuable data—consumers themselves," said Lowe.

TimiHealth's blockchain technology secures health data in an ecosystem that allows individuals to see who wants to purchase their data, to determine whether or not that data is shared and/or sold, and to actually profit from sharing their information by tokenizing and monetizing said data.

TimiHealth encourages all individuals to take immediate control of their data with an option to earn the majority of the profits from the sale of the data.

Retaking Control of your DNA Data:

  1. First, all available data should be downloaded from each genetics company website into the secure TimiDNA blockchain platform (available August 20, 2018 at www.timicoin.io).
  2. Next, consumers should opt-out of all data sharing and marketing activities for each organization that holds their DNA data and request that it be deleted from their databases (https://www.businessinsider.com/how-to-delete-dna-genetic-data-2018-5).

Starting August 20th the first 100,000 individuals who upload their DNA data to the TimiDNA private and secure platform will receive 20 Timicoins and unlike other DNA storage facilities, individuals participating in the Timicoin Giveaway will stay in total control of their DNA.

About Timicoin/TimiHealth:

The Mobile Health Record Platform provides decentralized medical records from storing to accessing instantly from anywhere in the world in a secure exchange. Timicoin/TimiHealth (Timicoin.io) is a patent-pending solution to securing patient data, while providing unprecedented portability. The company is actively working on pilot programs in the US, Mexico City and Monterrey, Mexico.

Media Contact: Adrienne Mazzone 561-750-9800 x2270; amazzone@transmediagroup.com

SOURCE TimiCoin/TimiHealth

Related Links

http://Timicoin.io

 

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Food and Health:

59% of Europeans and 68% of Americans are overweight

ReportLinker released a new report on eating habits, overweightness and obesity in developed countries:

  • Does living in a developed nation make people more self-conscious about what they eat?
  • Is obesity and overweightness approaching epidemic proportions?

 

Meat, Fruits and Veggies, what are the numbers?

- In the UK, veganism has become a trend. More people are favoring plant-based, low fat, and low sugar diets, and the weekly household consumption of beef has been divided by two since the 70’s (215g in 1975 vs 102g in 2015)

- In the US, red meat consumption has decreased since its peak of 198 lbs per person per year in 1971, to 141 lbs in 2015.

Also, the country saw a rise of 16% in vegetables consumption in the past 46 years.

Butter consumption has dropped too, going from 18 lbs consumed per person and per year in 1931, to an average of 4 lbs since the 80’s.

- Globally, the soy products consumption has highly increased since 2000 and is expected to    grow sharply through 2026.

What’s the impact on everyone’s weight?

  • Almost 70% US adults are considered to be overweight, way up from 41% in 1974.
  • We witness the same trend in Europe with 39% of people being overweight  in 1976 to 59% thirty years later.

 

To read the full story click here.

Health Food Innovator Edward & Sons Trading Company, Inc. – First To Introduce Miso-Cup® Instant Soup & Gluten-Free Baked Brown Rice Snaps® To American Consumers – Marks 40thAnniversary Milestone

CARPINTERIA, CA., AUGUST 6, 2018 - The first Whole Foods Market wouldn’t open in Austin, Texas, for another two years. The first Sprouts wouldn’t make its debut in Arizona for another 24 years. Vegetarians were relegated to the shadows in most supermarket settings, and for much of the population, the term Vegan sounded like something out of “Star Trek.”

The year was 1978 and the health food revolution was in its infancy. But a young man named Joel Dee with a vision of what the industry could one day become saw the future. And it was delicious.

As a young man, Joel worked alongside his two brothers and their father, Edward, in the family’s iconic New Jersey-based business, Smarties Candy Company. But, as fate would have it, Joel’s interests extended well beyond the confection industry.

“I was responsible for export sales at the candy company and found it difficult to maintain a healthy, satisfying diet while on-the-road,” Joel recalls today. “Health food stores sold wholesome foods that required a kitchen and a long cooking time, both in short supply to a `road warrior’ such as myself. Conventional supermarkets sold convenience foods that were laced with preservatives and artificial ingredients, which I was determined to avoid. To make things even tougher, I had recently become vegetarian, so my restaurant menu options were often limited to salad and potatoes... not exactly a balanced diet.”

Adds Joel, “I was a traveling salesman who needed portable, nourishing, easy to prepare vegetarian food without artificial ingredients, but I couldn’t find it anywhere in 1976 America. I wondered: Could I be the only person who wants this? I hadn’t planned to start a new business, but I felt somewhat obliged to.  If I wouldn’t take on the job of creating wholesome, vegetarian convenience foods, it occurred to me that no one else would either.”

With that motivation in mind, Joel began a two year effort to develop Miso-Cup® instant soup mix and, with its launch in 1978, Edward & Sons Trading Company, Inc. was born.

A History of “Firsts”  

As it turned out, introducing instant Miso-Cup soup would be only the first of numerous company innovations that would continue for the next forty years. In 1979, for example, Edward & Sons introduced Baked Brown Rice Snaps® whole grain, gluten free crackers, decades before American shoppers would demand gluten free groceries on a massive scale. Numerous “first-to-market” vegan organic products followed, including canned coconut milk, hearts of palm, pineapple chunks and mandarin oranges, Worcestershire sauce, croutons, panko, ice cream cones and many more.

According to Joel, “We tend to do`firsts’ because that’s what we’re passionate about. We are driven to provide new options to our health-aware consumers, while creating markets for our ethical organic farmers and packers around the globe. We’re proud of our activities that protect native forests and support conversion from conventional to organic farming, which nourishes the environment while enhancing the well-being of everyone along the supply chain from farm to table”

Indeed, Joel and his team have successfully developed so many different products over these past 40 years that they’ve chosen to create subsidiary brands to market and distinguish them all, including the flagship Edward & Sons® brand as well as Native Forest®,  Let’s Do Organic®, Let’s Do Gluten-Free®, More Than Fair®, Nature Factor®, Road’s End Organics®, Premier Japan® and The Wizard's®.

Regardless of the brand name on the package, however, all products under the Edward & Sons umbrella are defined by the company’s longstanding commitment to excellent vegetarian food and to its enduring motto: Convenience Without Compromise.®

As Joel sums up, “We remain a vegetarian company that’s mission-driven to offer consumers delicious and nourishing convenience foods free of artificial ingredients. That’s how we’ve run the business for the past 40 years and it’s how I envision Edward & Sons to be run for the next 40 years - and beyond.”

For more information, please visit www.edwardandsons.com

It’s Time To Permanently Legalize Hemp

 

[Kansas City, MO, August 6, 2018—] CBD American Shaman stands hand-in-hand with the U.S. Hemp RoundtableHelp us permanently legalize hemp across America by contacting your local representatives at hempsupporter.com/resources.

 

Every grass roots enterprise in our country was made possible by the passion, support, and love from its supporters and that’s why we are reaching out to you now.

 

Shortly, the decision will be made as to whether or not hemp will be viewed as the agricultural commodity it is, and not as a controlled substance. We are asking that you lock arms with us and join the movement to permanently legalize hemp

 

Our movement received strong backing as we recently learned that Mitch McConnell (R-KY) will be helping to lead the charge as he has personally named himself to the conference committee which means he will be in the room when the final decision regarding hemp will be handed down.

 

If you have been watching the impact hemp has been having on our friends, community, and even our economy, the decision to join us in support becomes a simple one. It was a leading cash crop grown by many of our nation's founders, and was critical to U.S. efforts in both world wars. While farming hemp was made illegal in the 20th century, imported hemp products have been sold in every state for decades, an almost billion-dollar import industry. We believe those jobs and economic opportunity belong in the U.S

 

Also, nothing is more grass roots than the farming industry and farmers are calling out to legalize hemp. The American Farm Bureau Federation and the National Farmers Union are calling for the passing of bi-partisan House and Senate bills that remove hemp from the Controlled Substances Act, and once that is done – with your help – it will release an exciting new industry that will stand for generations to come.

 

Senator McConnell went on record back in June regarding hemp to say, "Consumers across America buy hundreds of millions in retail products every year that contain hemp," McConnell said in a floor speech on Thursday. "But due to outdated federal regulations that do not sufficiently distinguish this industrial crop from its illicit cousin, American farmers have been mostly unable to meet that demand themselves. It's left consumers with little choice but to buy imported hemp products from foreign-produced hemp."

 

Support our great nation: American farmers producing American hemp supported with American dollars!

 

If you were one of the many who supported the legalization of hemp by writing your senator; donating time and other resources; we thank you and we’re asking that you continue to share with everyone you know. We need to make a strong push to support the Hemp Farming Act so that Senator McConnell is armed with not only his voice; but yours as well.

 

Help us legalize hemp across America and visit the website to make your voice heard. If you’ve experienced the incredible things hemp has done for you in your life, please share those stories as nothing will have a greater impact than personal testimonies.

 

Can we count on you to make sure this landmark bill passes by making your voice heard?

 

Visit hempsupporter.com/resources for additional information.

 

In 2009, then Governor of California Arnold Schwarzenegger signed the Donda West Plastic Surgery Law, requiring health checks be conducted prior to all major plastic surgery procedures in the state. This was following the death of rapper Kanye West’s mother. It was later determined that her heart attack was spawned by a combination of numerous postoperative complications and pre-existing coronary artery disease.  Today, women especially peruse Instagram and covet a perfect pout, perky derriere and firm breasts seen on Insta models. Just because you may desire cosmetic surgery does not mean you are physically or mentally fit for it NOW.  Dr. Stanley Poulos is a board certified San Francisco area plastic surgeon who takes steps to ensure the health and safety of his patients during surgery and post- operatively.  Here are some indicators Dr. Poulos looks for to assess patients for surgery.

 

Dr. Poulos stresses that it is essential for a surgeon to take a good medical history and exam of the patient.  Current and past illnesses, especially cardiac or pulmonary problems, surgeries, and medications should all be discussed.   Lab tests may be required on a case by case basis depending on patient history and planned procedures.

 

Urinalysis

When it comes to preparation for a plastic or cosmetic surgery procedure, a urinalysis can inform the doctor if you have certain types of infections, like a urinary tract (UTI), bladder, or kidney infection. Urine tests are also effective in detecting high blood pressure and diabetes.

 

Blood Count Test

Also known as a complete blood count (CBC), this blood test literally counts your blood. It takes note of the number of red blood cells, white blood cells, and platelets. This tells physicians if you’re anemic (red blood cell deficiency) or have a blood clotting disorder like hemophilia. CBC tests also detect infectious bloodborne diseases like HIV or hepatitis.

 

Heart function

Electrocardiogram (ECG or EKG)

Essentially, the ECG is a medical test that tells if your heart is in good condition through detecting any heart abnormalities by measuring the electrical activity of the heart when it contracts. Cosmetic surgery basically causes tremendous stress on the body, with the heart being one of the most important organs when it comes to stress response. That is why it is crucial for the doctor to assess whether your heart can endure the trauma during the operation.

 

Chest X-Ray

The Chest X-Ray is also one of the tests that may be required for your procedure. This is usually carried out to check the condition of your lungs and see whether you have breathing difficulties when you are put in anesthesia. This test is especially requested if you are a smoker or have a history of smoking. Signs of pneumonia or any breathing disorder may result to the postponement or cancellation of your surgery.

 

Smoking Use and History

Mixing nicotine with plastic surgery can result in problems:

Loss of cheek skin, nipples or tummy skin after a facelift, breast lift, breast reduction, or tummy tuck surgery

Infections

Death of fat cells (fat necrosis), causing hard lumps

Delayed wound healing

Thick, wide scars

Blood clots, which can be fatal

Increased pain

Permanent small vessel damage adding risk even if you quit

Loss of breast implants

Life-threatening complications like stroke, heart attack, blood clots, and pneumonia.

Mammogram

The mammogram is typically required for women who want to get breast augmentation or breast lift done. This is to help detect signs of breast cancer.

 

Psychological Screening

Although there is no formal psych test to assess a patient’s readiness and motives for cosmetic surgery, Dr. Poulos takes time with his patients to learn their reasons for desiring cosmetic change. Immediate red flags include, having surgery to try to keep a wayward spouse, an exaggerated concern over a minor problem, someone who seems addicted to cosmetic surgery, or a patient with body dysmorphic disorder. This syndrome is most appropriately treated by psychological treatment not surgical intervention.

 

Alcohol Habits

It is important not to drink alcohol before undergoing plastic surgery – or any type of surgery for that matter - as it can cause unforeseen complications and seriously impact final results and the way you heal. Alcohol, especially when consumed to excess, can dry out your skin, which can then result in cracks appearing. If you're having a plastic surgery procedure where skin is stretched (facelift, breast augmentation or abdominoplasty for example) then dry, cracked skin will make it harder for the surgeon to staple or stich the skin together, resulting in a less than optimum result and possibly scar.

 

Body Weight

Sometimes patients will enter a plastic surgeon’s office excited about a decision to finally move forward with breast or body contouring surgery, but then afterwards emerge having found out they are not currently a candidate because of excess body fat. This scenario is not only disappointing, but it can be an emotionally deflating and potentially embarrassing experience for patients. Dr. Poulos sympathizes with the emotional pain that such patients feel, and he wants to help them realize their goals. However, there are several specific reasons that your plastic surgeon might recommend weight loss prior to undergoing a procedure.  In addition, the results that you can achieve are likely to be much better if your weight is in a better range. Consider an overweight woman who wants breast reduction surgery.  Even when the breasts become smaller and more uplifted, it is extremely difficult for us to deal with the fullness lateral to the breasts (the “bra roll”), which significantly compromises the aesthetic result. In addition, it is much harder to get a beautiful transition between the breast and the abdomen due to the excess weight. On the other hand, let’s consider the patient that is overweight and wants a tummy tuck or liposuction. In this instance, the surgeon will not be able to remove all the excess fat in these areas, as it is technically challenging and can look odd as it is out of proportion to the surrounding fatty deposits. Even large volume liposuction cannot fully solve this problem. Body contouring surgery is great for shaping your body, but it is not a method or substitute for weight loss or weight control.  At Dr. Poulos’ clinic there is a full-time wellness/weight loss coordinator who helps patients achieve a healthy body composition ( body fat percentage and lean muscle mass balance) prior to undergoing body contour procedures.

 

What is an option for those who need to lose weight to be a better candidate for cosmetic surgery?

There is an FDA approved “Gastric Balloon” procedure that Dr. Poulos performs. It is appropriate for patients with a BMI of 30 to 40 that have not had previous weight loss surgery. Patients diagnosed with bulimia, binge eating, compulsive overeating, high liquid calorie intake habits or similar eating related psychological disorders are not good candidates. Dr. Poulos has now treated numerous patients who have successfully lost up to 20% of their body weight with the balloon procedures and have gone on to aesthetic body contouring with much improved results.

 

How does the balloon method work?

This non-surgical outpatient procedure begins with a diagnostic endoscopy to ensure that there are no contraindications and that it is safe to perform. Once the patient is mildly sedated and comfortable, the procedure can begin. The deflated gastric balloon is inserted through the esophagus and into the stomach. A syringe is then used to fill the balloon with a sterile saline solution. Once the weight loss balloon has been filled with saline, it expands to approximately the size of a grapefruit. The entire procedure takes about 20 minutes. Patients can usually return home after the placement or removal procedures within 30 minutes. Over the last 20 years this procedure has helped over 277,000 people. The gastric balloon encourages portion control while patients make healthy changes to diet and lifestyle.

 

How long does the balloon stay in place?

The balloon remains in the stomach for the first six months after the procedure. With the stomach balloon and Dr. Poulos’ support team, patients usually see the most drastic results in the first six months. It is very important to use this time to develop healthy habits that will continue for not only the 12-month weight loss program, but for the rest of one’s life.

 

What to expect after the balloon placement.

Over the first 14 days after placement, patients may experience nausea or vomiting. Dr. Poulos recommends a liquid diet for his patients during the first week to help manage these symptoms.  Also prescribed are effective anti-nausea drugs to help the patient through the initial stage.

 

How is the balloon removed?

Once the stomach balloon has been in place for six months the balloon is removed. The simple and non-surgical procedure is very similar to the placement process. Once the gastric balloon has been removed, it is very important to continue working closely with Dr. Poulos’ team and coaches to follow the personal diet and exercise plan provided. This will help to keep you in a positive and healthy mindset while achieving your weight loss goals.

 

About Dr. Stanley Poulos

Dr. Poulos specializes in cosmetic breast surgery and body contouring procedures. He helped pioneer the quick lift facial rejuvenation surgery in California and is recognized as one of the leading plastic surgeons in Marin County and the entire San Francisco Bay area.  Dr. Poulos and Plastic Surgery Specialists have extensive experience in body contour procedures. A graduate of the University of Texas Medical School, Dr. Poulos completed his internship and residency at UC San Francisco. He completed a plastic surgery fellowship at St. Francis Hospital in San Francisco and is certified by the American Board of Plastic Surgery. www.psspecialists.com

 

Menarini Ricerche to Sponsor Cancer Trial in Acute Myeloid Leukemia in USA

 

ROME, Aug. 6, 2018 /CNW/ - Menarini Ricerche, a company of the Menarini Group, announced today that the sponsorship of the ongoing Phase I/II study that is investigating MEN1703/SEL24 for the treatment of patients with relapsed/refractory (R/R) AML in the USA has been transferred from Selvita to Menarini Ricerche on June 30th 2018.

(Logo: http://mma.prnewswire.com/media/520214/Menarini_Ricerche_Logo.jpg)

Selvita S.A. and Menarini Group entered into a global licensing agreement for SEL24/MEN1703 on March 28th, 2017. Menarini Ricerche has assumed full responsibility for clinical development activities after a period of very productive collaboration with Selvita. "We are delighted at the achievement of this very important milestone in our collaboration with Selvita. Together with our partners at Selvita, we look forward to progressing in the development of MEN1703/SEL24, and to expanding our knowledge of its potential to improve the lives of patients affected by AML," said Andrea Pellacani, M.D., Ph.D. (General Manager, Menarini Ricerche).

MEN1703/SEL24 is a first-in-class orally available dual PIM/FLT3 kinase inhibitor with a unique activity profile currently investigated for the treatment of AML and with preclinical data suggesting potential activity in other hematological malignancies and solid tumors.

About Menarini

Menarini Group is an Italian pharmaceutical company, 13th in Europe out of 5,345 companies, and 35th company in the world out of 21,587 companies, with a turnover of more than 3.6 billion Euro and 17,000 employees. The Menarini Group has always pursued two strategic objectives: research and internationalization, and has a strong commitment to oncology research and development. As part of such commitment to oncology, Menarini, is developing four investigational new oncological drugs. Two of them are biologics, namely the anti CD157 antibody MEN1112, and the toxin-conjugated, anti CD205 antibody MEN1309. In addition, Menarini has recently added two small molecules to its oncology pipeline, the dual PIM and FLT3 kinase inhibitor MEN1703, and the PI3K inhibitor MEN1611, in clinical development for the treatment of a variety of hematological and/or solid tumors. Menarini is active commercially in the most important therapeutic areas with products for cardiology, gastroenterology, pneumology, infectious diseases, diabetology, inflammation, and analgesia.

With 16 production sites and 7 Research and Development centers, the Menarini Group has a strong presence throughout Europe and Asia, Africa, Central and South America. Menarini's products are available in 136 countries worldwide.

For further information please visit http://www.menarini.com

About Selvita

Selvita S.A. is a clinical stage drug discovery company engaged in the research and development of novel cancer therapies, as well as provision of integrated drug discovery services. Selvita is headquartered in Krakow, Poland, with offices in the USA (Greater Boston, San Francisco Bay), and in the UK (Cambridge). Selvita has currently several projects at early or late discovery stage. Drug discovery clients of Selvita include numerous large and medium-sized pharmaceutical and biotechnology companies from USA and Europe. The company is listed on the Warsaw Stock Exchange (WSE:SLV).

For more information please visit https://selvita.com/

SOURCE Menarini Ricerche