The Economic Club of Canada: The Life Sciences Industry of Tomorrow: Healthy Canadians, Healthy Future

OTTAWA, Oct. 30, 2017 /CNW/ - What is the true contribution of the innovative pharmaceutical industry to the Canadian economy and R&D investment? What are the potential impacts of federal policy changes aimed at lowering drug prices? Is there a middle ground where Canada is able to lower prices while still retaining its position as a top tier destination for clinical trials and the launch of new innovative medicines? Innovative Medicines Canada President Pamela Fralick and panelists will discuss the results of a Fall 2017 analysis by Ernst & Young about industry's contributions to Canada and how industry and government can work together to enhance affordable, equitable and timely access to new therapies.

The event will be broadcast live over the internet at http://collaboratevideo.net/imc-mnc

Innovative Medicines Canada President Pamela Fralick will be available for media interviews after the event.

 

WHO: Speakers

Pamela C. Fralick: President – Innovative Medicines Canada

Moderator
Connie Côté, Chief Executive Officer, Health Charities Coalition of Canada
Panelists
Dr. Bill Cameron, Senior Scientist, Division of Infectious Diseases and Respirology, Medical Director, Clinical Research, Ottawa Hospital Research Institute
Ed Dybka, President and CEO – AstraZeneca Canada Inc.
WHEN: Tuesday, October 31, 2017 (11:30am-1:30pm)
11:15 am Registration begins
12:15 pm Opening remarks begin
12:25 pm Keynote speech begin
12:40 pm Panel
1:10 pm Q&A
1:30 pm Event concludes
WHERE: Fairmont Chateau Laurier
1 Rideau Street, Ottawa
Drawing Room

 

About Innovative Medicines Canada

Innovative Medicines Canada is the national voice of Canada's innovative pharmaceutical industry. We advocate for policies that enable the discovery, development and commercialization of innovative medicines and vaccines that improve the lives of all Canadians. We support our members' commitment to being valued partners in the Canadian healthcare system.

I was recently sent a new product to try. And I will tell you right away that my honest review is I love it!

According to Genuine Health "Turmeric is the spice that’s been trending everywhere this year! Not only is it in facials, bowls and lattes, it’s also one of nature’s anti-inflammatory ingredients that helps with pain relief and joint function. Genuine Health’s NEW fast jointcare+ with fermented turmeric is an all-natural, non-GMO, gluten-free and soy-free alternative to Tylonel and Advil and improves physical functioning.

With the help of BiovaFlex®, natural eggshell membrane, Genuine Health’s fast jointcare+ with fermented turmeric relieves pain ranging from athletic injuries to headaches and cramps, while decreasing inflammation. BiovaFlex is the fastest, most effective natural pain relief ingredient on the market and it works in only 5 days! Don’t take remedies that just mask pain, but provide your body with whole food support to actually nourish and repair joints. With the addition of a simple, natural ingredient like turmeric – become pain free so you can lead a healthy active lifestyle moving forward."

Being a competitive athlete my entire life i have put body through vigorous strains of inflammation build up and tearing of muscles and joints. Before trying Fast joint care+ I found a sense of discomfort daily with symptoms of aches and pains. After incorporating Fast joint Care+ in my daily routine I found that just after 6 days I was able to notice a change in my overall range of motion as well as my pain discomfort decreased.

As a competitive athlete it is very crucial to keep my inflammation down through out my workouts. With that being said, I have quickly noticed fast pain relief and more flexibility within my joints. I strongly believe in Fast Joint care+, I recommend it to all my clients. Not only do I love the benefits of fast joint and pain relief but the fact that you only need to take one easy to swallow tablet a day. It has turmeric in it which has been known to be very good at reducing inflammation. I in fact use the space all the time when I cook.

Thanks or sending me the product to try Genuine Health! It's now part of my regular supplement Regiment!

 

Food Safety Tips—From Start to Finish—For Thanksgiving Dinner

For most people, Thanksgiving dinner is the biggest and most busily prepared meal they cook all year. From menu planning to handling leftovers, there are many opportunities for slip ups to contaminate food. Stop Foodborne Illness, a national, nonprofit, public health organization dedicated to preventing illness and death from foodborne pathogens, is giving cooks a hand with tips for reducing the risk of foodborne illness every step of Thanksgiving Day.

Food safety starts at the grocery store. Brush up on these preparation tips to ensure dinner starts on a safe note.

  • Separate goods when shopping . Keep raw poultry, meat and seafood away from other food as much as possible. A simple way to prevent meat juices from dripping onto other groceries is by putting these items in separate plastic bags (brought from home or provided by the store) as you shop. Pro Tip: put perishable items, like meat and poultry, in your cart last.
  • Buy the right bird . Whole turkeys are sold fresh or frozen and buying the right one is crucial. For those who do their Thanksgiving shopping in advance, Stop suggests selecting a frozen bird to reduce the risk foodborne illness. Those who prefer serving a fresh turkey should purchase it within two days of Thanksgiving dinner.
  • Shop and drop (groceries off at home). Though it can be tempting to run errands or browse early Black Friday sales after grocery shopping, food should not be left in the car for long periods of time as dangerous microorganisms can contaminate produce and poultry. Go home immediately and store food in the refrigerator, freezer or pantry before doing anything else.
  • Defrost safely . There are three safe ways to defrost a turkey: in the refrigerator, cold water or microwave. Refrigerator thawing takes the longest—24 hours for every 5 pounds of turkey—but is the best method since it uses the least amount of labor and will defrost at a consistent, safe temperature (a 15 lb. turkey will take 3 days). To thaw in cold water, submerge the bird in its original wrapper in cold water, changing the water every 30 minutes. This method takes less time, but requires more attention. Estimate 30 minutes per pound (a 15 lb. turkey will take 7.5 hours, and 15 water changes). For those who forgot to defrost until the last minute and need to thaw fast, refer to your owner’s manual for instructions on microwave defrosting. Pro tip: defrost in advance. A thawed turkey can be kept in the fridge (40°F or below) for up to 4 days.

On Thanksgiving, there is no such thing as too many cooks in the kitchen; having family home to prep, cook and bake together is one of the best things about the holiday. However, having so many helping hands increases the chance of spreading germs. Avoid disaster by reviewing these helpful food safety hints with your kitchen crew.

  • Wash hands, not the bird. According to an FDA Food Safety Survey, 68% of people wash whole turkeys before cooking. However, rather than getting rid of bacteria, the splashing water allows harmful pathogens to contaminate other areas—like sinks and food prepping surfaces—up to three feet away. Banish bacteria by washing hands before and after handling raw poultry, meat or seafood.
  • Know your stuff. Traditional stuffing is one of the Thanksgiving foods most susceptible to foodborne illness since harmful bacteria can survive in stuffing that does not reach 165°F. Avoid disaster by putting the stuffed bird in an oven, set to 325°F or higher, immediately after preparation and use a food thermometer to ensure the stuffing reaches the safe minimum internal temperature (165 °F).
  • Better yet, think outside the turkey. Although dressing—preparing stuffing outside of a turkey—is safer, cooks still need to be aware of potential foodborne illness. If using raw meat, poultry or shellfish in the dish, precook the raw ingredients separately first.
  • Cook to the right temperature . The only way to determine if meat, poultry or seafood is cooked safely is to check the internal temperature with a food thermometer. Whole turkeys should register 165°F in three locations—the innermost part of the thigh, the innermost part of the wing and the thickest part of the breast.

The best part of Thanksgiving is leftovers! Don’t let post-dinner drowsiness get in the way of food safety and packing up remaining food properly.

  • Chill out. We mean your food, not you! Refrigerate uneaten food within two hours of cooking to prevent bacteria growth. Stop suggests storing leftovers in shallow containers to decrease cooling time and prevent food from spending too much time at unsafe temperatures (40 °F to 140 °F). Pro tips : cut turkey off the bone before refrigerating and store stuffing separately from the meat.
  • BYOC (Bring Your Own Cooler). Thanksgiving means refrigerator space is at a premium. Anticipate little to no refrigerator space and bring a cooler from home. Even if you live in a cold climate, do not use the outdoors as a fridge since temperatures can fluctuate. The best way to keep extra food pathogen-free is in a packed cooler at a safe temperature (40°F or below).
  • Leftovers last safely for four days in the refrigerator. For those who need a week before eating Thanksgiving again, pack food into airtight containers and freeze.
  • Sending guests home with leftovers? If they will be traveling for more than two hours, give them ice or frozen gel packs to make sure the food in their coolers stays at or below 40°F.

About Stop Foodborne Illness
Stop Foodborne Illness is a national nonprofit, public health organization dedicated to preventing illness and death from foodborne pathogens by advocating for sound public policies, building public awareness and assisting those impacted by foodborne illness. For more food safety tips please visit www.Stopfoodborneillness.org/awareness/. If you think you have been sickened from food , contact your local health professional. You may subscribe to receive Stop Foodborne Illness e-Alerts and eNews here: www.Stopfoodborneillness.org/take-action/sign-up-for-e-alerts/.

Follow Stop’s latest news at www.newsline360.com/stopfoodborneillness.
Follow Stop on Facebook at www.facebook.com/stopfoodborneillness.
Follow Stop on Twitter: www.twitter.com/StopFoodillness.

Change the Clocks Not Your Mood with These 5 Steps

As we prepare to switch the clocks and “fall back” this November 5, many of us may give up more than an hour of daylight. We may be giving up our good mood. Many people mark the clock change as the start of more darkness, cold weather and anxiety over holiday schedules and holiday shopping and travel. Dr. Saman Hafeez, a NYC based licensed clinical psychologist, teaching faculty member at the prestigious Columbia University Teacher’s College and the founder and Clinical Director of Comprehensive Consultation Psychological Services explains how setting the clocks back is, for many people the start the winter blues and offers tips on how not to slip into a funk.

Set a sleep regimen.

Less daylight affects our mood and the further north you go the more intense it is. Dr. Hafeez explains that around 3 million people are affected by some form of Seasonal Affective Disorder. It’s more common in women than in men and it often lingers throughout the entire winter. How to beat it? Dr. Hafeez suggests getting to bed an hour earlier and adding in some time to wind down an hour before bed. “Don’t watch the news before sleep; read a book, write in a journal or meditate. Do something that eases you into a restful state,” she says.

Change up your exercise schedule.

It’s normal for the brain to get thrown off when it gets darker earlier. Less daylight means that the motivation to get outside for that early morning jog may fade. This is normal. “It’s important that you give your brain new stimulation. Try working out after work instead of in the morning or, if possible join a work out app that brings at home exercise routines right to your phone.

Book your calendar.

The more you have to look forward to the better your mood will be. Schedule weekly dinners with family and friends. Wintertime is hibernation time so set up a family movie schedule or game nights. It’s important to have weekends booked up with fun activities to keep the mind looking forward to fun events. “Social withdrawal is common in the winter when temperatures drop. Take turns hosting dinner events and get around people,” Hafeez encourages.

Study up!

Interested in learning a new skill? Use the wintertime to take seminars, attend workshops and commit to learning something new. When you engage the part of your brain responsible for learning you’re more inspired and alert. Even listening to podcasts and participating in interesting webinars on a topic you’re interested in will increase energy, Hafeez says.

Experiment with new recipes.

When the temperatures drop and we enter hibernation mode we tend to crave more comfort foods. According to Dr. Hafeez, a great way to lift our moods and stimulate our brains is through taste. Winter is a great time to explore new foods. With so many fresh food delivery companies out there you can get pre-portioned healthy food options with step-by-step prep instruction delivered to your doorstep. “I really like this idea because it engages the senses which stimulates the brain. You’re releasing positive brain chemicals triggered by excitement, adventure, task execution and enjoyment, plus you’re eating healthy.

About the doctor:

Dr. Sanam Hafeez PsyD is a NYC based licensed clinical psychologist, teaching faculty member at the prestigious Columbia University Teacher’s College and the founder and Clinical Director of Comprehensive Consultation Psychological Services, P.C. a neuropsychological, developmental and educational center in Manhattan and Queens. 

Dr. Hafeez masterfully applies her years of experience connecting psychological implications to address some of today’s common issues such as body image, social media addiction, relationships, workplace stress, parenting and psychopathology (bipolar, schizophrenia, depression, anxiety, etc…). In addition, Dr. Hafeez works with individuals who suffer from post-traumatic stress disorder (PTSD), learning disabilities, attention and memory problems, and abuse. Dr. Hafeez often shares her credible expertise to various news outlets in New York City and frequently appears on CNN and The Doctors.

According to a report published by Grand View Research, the Global Aromatherapy Market is anticipated to reach USD 2.35 billion by 2025 and includes inhalation as a third of the market size. Aromatherapy is expected to play a significant role in the field of alternative medicines with a gradual shift from man-made drugs toward essential oils to gain therapeutic values.  WHY?

Because life is a rat race and requires a deeper integration of science and wellness in order to battle our everyday stresses.

Kinin offers a portable wellness accessory that delivers the benefits of an essential oil diffuser in a portable package no larger than the size of a pen. Each of our blends are designed to be inhaled using vapor technology to mobilize the benefits from nature’s naturally occurring aromatic compounds to immediately create a positive physiological effect: relaxing effortlessly, recovering quickly, and achieving a superior focus.

The Science Behind It:

You’re affecting the kynurenine pathway, hence KININ.  In essence, the integration of these chemicals through the intranasal delivery system allows for the chemicals to be shared quickly (minutes) with the hypothalamus and amygdala and a little later to the superior temporal gyrus. The immediate effect regardless of the chemical is an instant reduction in the inflammatory pathways dependent on kynurenine and its metabolites. This is neuroprotective and provides the body with a bit of a reset.

Then, based on the type of volatile active ingredient, other pathways will be invoked. For Kinin Relax, it’s GABA. For Kinin Focus, it’s the norepinephrine, and for Kinin Recover, it’s the terpenes that our body sense as indicators of health.

Kinin is the most effective way to use natural chemicals to invoke neurological responses and here's how to use in life's daily activities:

FOCUS: Before exercise or intensive mental activity like writing

RECOVER: Post Workout or to fight off an oncoming cold

RELAX: Before Bed or during high stress/anxiety sensations throughout the day

BD - Canada Marks Canadian Patient Safety Week, Joining the Call for a Safer Health Care System

MISSISSAUGA, ON, Oct. 26, 2017 /CNW/ - In recognition of Canadian Patient Safety Week (CPSW), occurring Oct. 30 – Nov.3, BD (Becton, Dickinson and Company), a leading global medical technology company, is joining the national effort to raise awareness of patient safety in Canada, with a specific focus on medication safety and patient empowerment.

It is estimated that patients experience preventable harm in one of every 18 hospitalizations, and up to 37 percent of these may be attributable to errors in the management of medications1. To help reduce and eliminate these occurrences, the theme for this year's Canadian Patient Safety Week is Take with Questions – where patients are encouraged to ask questions and have an open dialogue with their health care provider about medication.

"BD - Canada is supporting patient safety by standing behind health care providers, to help improve the patient experience and patient outcomes," says Anuj Pasrija, vice president, Market Access and Government Affairs for BD - Canada. "We believe that quality health care is a team effort. Both patients and health care workers benefit when health care workers are provided with the right tools and systems for quality care."

Canadian Patient Safety Week is led by Canadian Patient Safety Institute (CPSI), an organization dedicated to advocating for safer health care practices across the nation. BD - Canada is supporting CPSI's list of "5 questions to ask about your medications," as well as encouraging health care providers in the workplace to be informed.

"Medication use is so common, and a fact of life for many people these days, that we were compelled to find better ways to keep people safe," said Chris Power, CEO, Canadian Patient Safety Institute. "We believe these five questions will bring much needed clarity to complex situations, and we encourage everyone to ask them in every care setting across Canada."

Canadian Patient Safety Week is an annual, nation-wide event, first launched in 2005. Canadians can join the conversation by using #asklistentalk.

About BD

BD is a global medical technology company that is advancing the world of health by improving medical discovery, diagnostics and the delivery of care. BD leads in patient and health care worker safety and the technologies that enable medical research and clinical laboratories. The company provides innovative solutions that help advance medical research and genomics, enhance the diagnosis of infectious disease and cancer, improve medication management, promote infection prevention, equip surgical and interventional procedures, optimize respiratory care and support the management of diabetes. The company partners with organizations around the world to address some of the most challenging global health issues. BD has nearly 50,000 associates across 50 countries who work in close collaboration with customers and partners to help enhance outcomes, lower health care delivery costs, increase efficiencies, improve health care safety and expand access to health. For more information on BD, please visit bd.com.

1 Canadian Institute for Health Information, Canadian Patient Safety Institute. Measuring Patient Harm in Canadian Hospitals. What can be done to improve patient safety? Authored by Chan B, Cochrane D. Ottawa, ON: CIHI; 2016. Baker GR, Norton PG, Flintoft V, Blais R, Brown A, Cox J, et al.

SOURCE BD - Canada

Manulife Study Finds Canadians Struggle to Discuss Financial Challenges Due to Shame and Embarrassment

 

  • 93 Per Cent of Counsellors* Believe Financial Challenges Affect Work and Productivity

TSX/NYSE/PSE: MFC
SEHK: 945

WATERLOO, ON, Oct. 25, 2017 /CNW/ - Manulife today announced the results of its latest study on health and wealth, this year finding that feelings of shame and embarrassment often impede Canadians from acknowledging their personal financial struggles. According to professional Counsellors surveyed in this study, conducted in partnership with Homewood Health Inc., these emotional barriers often have a negative impact on the health of Canadians.

The study shows that these feelings can lead to a perpetual cycle of mental and physical health problems, reducing both quality of life and productivity at work. The professional Counsellors responded that many Canadians are unable to talk about their own financial challenges because of their intimate nature, with one stating "It's very personal, sometimes more personal than sex. When I ask clients if they want to talk about money they are not very open."

"The stigma, shame and embarrassment of being financially unwell often prevents people from taking action to address and overcome these issues," said Sue Reibel, Executive Vice President & General Manager, Group Benefits & Retirement Solutions at Manulife. "We believe that the industry as a whole has a bigger role to play in helping remove these stigmas. Only once an individual is comfortable discussing their own money problems, can they begin to take steps to address them."

Key Findings of the Emotional Barriers to Financial Wellness – 2017 Study Include:

  • Nearly half (46 per cent) of professional Counsellors feel it is difficult for individuals suffering from financial health issues to reveal these issues mainly due to shame and embarrassment;
  • 74 per cent of professional Counsellors feel that personal finances have a high impact on emotional and mental health;
  • Half the time financial challenges are an underlying element beneath the issues for which people seek support from Counsellors;
  • Only one in three professional Counsellors see people making the connection between their finances and other life problems.

"Our industry can help remove these stigmas by encouraging those going through financial challenges to discuss these problems more openly, and to take advantage of free and accessible tools that help alleviate financial distress, which can lead to anxiety, depression and stress," added Reibel.

*Professional Counsellors are defined as those professionals that address a full range of mental health issues including but not limited to family and relationship issues, trauma, depression, anger management, life transitions and personal issues.

Methodology

The study was conducted between April 2016 and July 2017 in three phases, starting with qualitative interviews with nine professional Employee and Family Assistance Program (EFAP) Counsellors.  This was followed by a quantitative survey of 223 EFAP Counsellors.  The final phase was five key qualitative interviews with professional EFAP Counsellors.

About Manulife

Manulife Financial Corporation is a leading international financial services group that helps people achieve their dreams and aspirations by putting customers' needs first and providing the right advice and solutions. We operate as John Hancock in the United States and Manulife elsewhere. We provide financial advice, insurance, as well as wealth and asset management solutions for individuals, groups and institutions. At the end of 2016, we had approximately 35,000 employees, 70,000 agents, and thousands of distribution partners, serving more than 22 million customers. As of June 30, 2017, we had over $1 trillion (US$780 billion) in assets under management and administration, and in the previous 12 months we made $26.7 billion in payments to our customers. Our principal operations are in Asia, Canada and the United States where we have served customers for more than 100 years. With our global headquarters in Toronto, Canada, we trade as 'MFC' on the Toronto, New York, and the Philippine stock exchanges and under '945' in Hong Kong.

SOURCE Manulife Financial Corporation

From Couch to 5K

I would say I'm your average couch potato. I eat a lot of junk, I rarely ever exercise and I'm overweight... actually obese. So when my friends came to me with the idea to run a 5K, all I really could do was laugh. I doubted myself, but I accepted the challenge. I started training, but life happened, I learned though that this was just another excuse and one of the reasons I had gained so much weight and found myself unhappy. I decided to run the 5K anyway. After the experience, I have simply one statement to make: life changing.
I learned 5 things that I want to share with fitness enthusiasts and couch potatoes both. Check them out below:
*It's all mind over matter
It's not if you can do it, it's all about if you believe in yourself. As I found myself running and being passed up by those old enough to be one of my grandparents and those even bigger in size than me, I realized it was literally all mind over matter. It wasn't about if I was super athletic. It was about if I could push myself and believe that I could finish. It was apparent with myself and all the others that participated in the race.
*Excuses are not legit reasons you didn't do something, they're EXCUSES
After this experience, I realized so much about myself. I was in the position I was (not just physically but mentally, financially and spiritually) because of the story and stories that I had been telling myself. They were all excuses. Too busy, an excuse. Tired, an excuse. Not feeling well, an excuse. Too early, an excuse. Too late to train, an excuse. The reason I or you aren't in the place you want to be, no matter the place, is because of you. Don't come up with reasons why you aren't doing what you need and want, they're just excuses.
*The only opinion that matters is my own. 
I've noticed in my life that I'm always concerned with what others think. What they think about me, what I'm doing, etc. Well as I found myself running in that 5K I realized that it didn't matter. Especially when most of the time, people aren't even thinking about you. The girl heavier than me, outrunning me, wasn't concerned about what I thought about her, she didn't even care. It was apparent that all she was concerned about was doing her best and completing the task at hand of which she did fabulously at completing that task! If you're putting forth effort, and doing your best, it doesn't matter what people say or think.
*It's All About Putting One Foot in Front of the Other
Literally and figuratively. It's about doing. Putting forth effort. Putting forth energy and effort just brings more energy and brings you closer and closer to your goal. Not just in running and in fitness and exercise, but in LIFE!
*There's always someone cheering you on, even if you don't know them. 
The support and camaraderie that's at a race is unbelievable. You have people that you've never seen in your life, you don't even know, will never see again, pushing you and encouraging you to do your best and finish. Maybe one of the best feelings in the world. In life sometimes we tend to focus so much on "the haters" and "proving someone wrong" when there's someone someone that doesn't even know you cheering for you!
These are just some of the things I learned as I pushed myself through my physically daunting task that I wanted to share... anonymously! Hope this encourages you to sign up for a 5K with a great cause or push yourself to do something that you never thought you could do! It just may lead to the spark that will change your life.
Happy running!

FDA Approves Soliris to Treat

Generalized Myasthenia Gravis

 

Press Release: FDA Approves Soliris (Eculizumab) For The Treatment of Patients With Generalized Myasthenia Gravis (gMG)

Summary: Alexion Pharmaceuticals announced Sept. 23, 2017, that the U.S. Food and Drug Administration (FDA) has approved eculizumab (brand name Soliris) as a treatment for adult patients with generalized Myasthenia Gravis (gMG) who are anti-acetylcholine receptor antibody-positive. Soliris is the first in a new class of drugs to be approved for MG in the U.S.

Soliris is not a cure for MG, but it may lessen the symptoms experienced by people living with generalized MG. Soliris was tested in clinical trials in patients who had previously failed immunosuppressive treatment and continued to suffer from significant unresolved disease symptoms such as difficulties seeing, walking, talking, swallowing and breathing. Patients taking Soliris had improved scores on scales designed to assess quality of life and symptom burden including double vision, ptosis (drooping of the eyelids), swallowing, speech, breathing, and use of arms and legs.

Statement from MDA President and Chief Executive Officer Lynn O’Connor Vos: 

MDA celebrates the approval of Soliris to treat generalized myasthenia gravis — the first in a new class of drugs to be approved for MG in the U.S. — and we offer our deepest thanks to the dedicated researchers, and the individuals and families who participated in clinical trials to make this development possible.

“This is truly an unprecedented time, when more experimental therapies than ever before are reaching late-stage development and moving through the regulatory review process. In just the past few years, our community has seen six FDA approvals for drugs to treat neuromuscular diseases in MDA’s program — including periodic paralysis, Duchenne muscular dystrophy, ALS, spinal muscular atrophy and now myasthenia gravis. The origins of four of those six drugs can be traced directly to MDA research dollars.

“We are closing in on solutions for people living with neuromuscular diseases and will continue to fund critical scientific research, facilitate clinical trial participation, and advocate for policies that enable safe and effective therapy options to be made available as quickly as possible.”

Background: Patients with generalized MG experience muscle weakness in the head, neck, trunk, limb and respiratory muscles. An estimated 10-15 percent do not respond to treatments that are typically helpful in other MG patients.

Profound weakness throughout the body often is accompanied by slurred speech, impaired swallowing and choking, double vision, upper and lower extremity weakness, disabling fatigue, shortness of breath due to respiratory muscle weakness, and episodes of respiratory failure. Patients with generalized MG may require hospitalization, often involving intensive care unit stays.

Soliris is a terminal complement inhibitor that targets a part of the immune system called the complement system, which is responsible for helping antibodies clear damaged cells and potentially toxic microbes that could cause infections. In MG, antibodies whose job it is to target these toxic pathogens, instead inappropriately recruit the complement system and target the space across which nerve fibers transmit signals to muscle fibers, called the neuromuscular junction (NMJ). In patients with anti-acetylcholine receptor antibody-positive MG, the body’s own immune system turns on itself to produce antibodies against the acetylcholine receptor, a receptor located on muscle cells at the NMJ, activating the complement system. Soliris is thought to work in MG by inhibiting the complement pathway to prevent destruction of the neuromuscular junction.

MDA has not been directly involved in the development of Soliris for MG, but we have invested in previous research investigating complement inhibition as a therapeutic strategy for MG. In addition, MDA currently is funding research focused on developing improved complement inhibitors. (Soliris is a complement inhibitor drug.)

A hard look at Ontario's health system

 

TORONTO, Oct. 23, 2017 /CNW/ - Measuring Up 2017 – Health Quality Ontario's 11th yearly report on the health of Ontarians and how the health system is performing – shows that people in the province are living longer and are losing fewer years of their lives to premature death.

The report contains other positive findings that show many parts of Ontario's health system are working well or better than before:

  • More patients are receiving cancer surgery within maximum wait time targets.
  • More people are getting high-priority MRI and CT diagnostic scans within maximum wait time targets.
  • Care for residents in long-term care homes is improving.
  • More people are being screened for colorectal cancer.
  • People are receiving primary care consistently from the same doctor.

However, Measuring Up 2017 also shows Ontario's health system still faces significant challenges, such as people having to wait too long for certain forms of care, not getting the care they need as they transition between parts of the system, or not having equitable access to care. The report identifies several areas where improvements in access, transitions and equity are needed:

  • More hospitals beds are occupied by patients waiting for care elsewhere.
  • Patients are experiencing longer delays when they need to be moved from the emergency department to an inpatient hospital bed.
  • People with a mental illness or addiction continue to face difficulties in accessing mental health care.
  • People who live in certain regions or have lower incomes sometimes have poorer access to health care.
  • Informal caregivers of home care patients are increasingly distressed.
  • Fewer patients are having surgery within target wait times for hip and knee replacements.

Compared to other provinces and countries, Ontario's performance is mixed. Ontario has the lowest rate of premature mortality of any province in Canada, and performs best or second-best in key aspects of long-term care. However, compared to 10 socioeconomically similar countries, Ontario ranks last in access to primary care appointments on the same day or next day when patients are sick, and in the middle of the pack when it comes to patients' ability to pay medical expenses not covered through private or provincial insurance plans.

"This year's Measuring Up report shows that the work done in Ontario to improve health system performance in key areas such as wait times for cancer patients and resident care in long-term care homes has clearly brought positive results," says Joshua Tepper, president and CEO of Health Quality Ontario. "The report also shows many challenges remain that need to be the focus of ongoing efforts to provide the best health care for all Ontarians."

Measuring Up 2017 also includes stories detailing the personal experiences of patients, caregivers and health care providers to illustrate the real-life impact of the health system on real people.

Quick facts

Findings in areas that are doing well or improving

  • The rate of potential years of life lost (in deaths before age 75) improved by 17.6% in Ontario between 2003 and 2013, to 4,221 years per 100,000 people, from 5,120. Ontario has the lowest rate of potential years of life lost among Canadian provinces.
  • The proportion of cancer surgeries completed within provincial maximum wait time targets increased overall between 2008/09 and 2016/17. Depending on the priority level of the surgery, the number of cancer patients who had surgery performed within target ranged from 78% to 93%.
  • Between 2012/13 and 2016/17, the proportion of patients who had their diagnostic scan completed within the provincial maximum wait time target increased to 82% from 79% for Priority 2 MRI scans, and to 96% from 92% for Priority 2 CT scans.
  • The proportion of long-term care home residents without psychosis who were given antipsychotic medication fell to 22.9% from 35.0% between 2010/11 and 2015/16, while the proportion physically restrained on a daily basis declined to 6.0% from 16.1%, and the proportion who experienced moderate pain daily or any severe pain fell to 6.1% from 11.9%.
  • The proportion of Ontarians overdue for colorectal cancer screening decreased to 38.7% in 2015 from 43.6% in 2011.
  • Among Ontarians who had at least three primary care visits to a physician within the previous two years, 57.3% had high continuity of care from the same doctor, 27.4% had medium continuity, and 15.2% had low continuity, in 2015/16.

Findings in areas that need improvement

  • An average of 3,961 Ontario hospital beds per day were occupied by patients waiting to receive care elsewhere in 2015/16. Those 3,961 beds were the equivalent of 10 large hospitals.
  • For patients who were admitted to hospital, the average length of stay in emergency increased 10.9% to 15.2 hours in 2016/17 from 13.7 hours in 2015/16.
  • Between 2006 and 2015, about a third of people who went to the emergency department for a mental health condition had not received mental health care from a primary care doctor or psychiatrist over the previous two years.
  • The rate of potential years of life lost was nearly 2.5 times higher in the area of the province with the highest rate – the North West Local Health Integration Network (LHIN) region – at 7,647 years per 100,000 people, than in the region with the lowest rate – the Central LHIN region – at 3,026 years per 100,000 population, during the 2010-2012 period.
  • Among urban residents, those who lived in the lowest-income neighbourhoods had the highest rate of being overdue for colorectal cancer screening in 2015, at 46.5%, while those who lived in the highest-income neighbourhoods had the lowest rate of being overdue, at 32.7%.
  • In the first half of 2016/17, among long-stay home care patients with at least one informal caregiver, 24.3% had caregivers who experienced continued distress, anger or depression in relation to their caregiving role, compared to 21.2% in the first half of 2012/13. That was a 14.6% increase over a four-year period.
  • In 2016/17, the proportion of patients who had Priority 4 knee replacement surgery within the wait target fell to 80% from 85%, so that 1 in 5 had to wait longer than the maximum wait target of six months. Priority 4 is the category of knee replacement with the greatest number of surgeries.

To read the full report visit: www.hqontario.ca/MeasuringUp2017

About Measuring Up
Measuring Up 2017 is Health Quality Ontario's 11th yearly report to Ontarians on health system performance. Its findings are based on data from a set of about 50 health system indicators, called the Common Quality Agenda, developed in association with health care experts and health system partners such as doctors, nurses, hospitals, local health integration networks and home care providers, as well as patients and their families and caregivers. This year's report highlights findings from 28 indicators.

About Health Quality Ontario
Health Quality Ontario is the provincial advisor on the quality of health care. With the goal of excellent care for all Ontarians, Health Quality Ontario reports to the public on how the system is performing, develops standards for what quality care looks like, evaluates the effectiveness of new health care technologies and services, and promotes quality improvement aimed at sustainable positive change. Visit www.hqontario.ca for more information.

SOURCE Health Quality Ontario