New Canadian investments in ALS research reflect growing knowledge about the disease and increasing likelihood of effective treatments being developed
ALS Canada and Brain Canada award $4.5 million in research funding; nearly $20 million
invested in ALS research in Canada since 2014's Ice Bucket Challenge
The ALS Society of Canada (ALS Canada), in partnership with Brain Canada, today announced $4.5 million in funding for nine new ALS research projects. This means that since the Ice Bucket Challenge became a social media phenomenon in 2014, nearly $20 million has been invested in Canadian ALS research at a time when it has the potential to make the greatest impact.
ALS, or amyotrophic lateral sclerosis, is a disease that gradually paralyzes the body, leaving people without the ability to move, talk, swallow and eventually breathe. Most people die within two to five years of being diagnosed with ALS because the disease has no effective treatment or cure. However, ALS research has advanced to a point that many ALS research experts believe effective treatments are now a matter of 'when' not 'if.'
"We hear often from people and families living with ALS that the promise of research discovery is something they can be hopeful about. The challenge is that research takes time, which is exactly what people living with ALS don't have – and why the Ice Bucket Challenge has been such a game-changer," said Tammy Moore, CEO of ALS Canada. "Because of the increased funding that the Ice Bucket Challenge has made available, we have been able to make more significant research investments than ever before. We are grateful to Canadians who donated to the Ice Bucket Challenge, to our ALS Society partners across the country and to Brain Canada and the federal government's Canada Brain Research Fund for making this research investment possible."
"Brain Canada's partnership with ALS Canada has enabled greater investment in ALS research, which will in turn accelerate progress towards the development of effective treatments," said Inez Jabalpurwala, President and CEO, Brain Canada Foundation. "In addition, the discoveries that will result from this research funding have the potential to inform how we approach other neurodegenerative diseases with similar underlying mechanisms."
The nine projects include two large-scale, multi-year team initiatives – one of which is using stem cell technology to better understand and potentially treat ALS, while the other is studying in a new way the gene most commonly linked to ALS development – and seven smaller studies that enable investigators to explore out-of-the-box research.
"Five years ago, the breadth of ALS research we are funding today would not have been possible simply because we didn't know enough about the disease to be able to ask the kinds of questions that today's researchers are investigating in their work," said Dr. David Taylor, Vice President of Research at ALS Canada. "The fact that we now have the ability to explore ALS from different angles reflects the growing body of knowledge about the disease and the increasing likelihood of effective treatments being developed."
A research team led by Dr. Guy Rouleau of McGill University and the Montreal Neurological Institute has been awarded $2.2 million to study motor neurons and astrocytes created from people living with different forms of ALS via stem cell technology. Dr. Rouleau and his team, which includes other collaborators at McGill University and the Montreal Neurological Institute as well as Université de Montréal and Université Laval, will study the biology of these stem cells to determine if their characteristics in the laboratory can represent different forms of human disease and further develop them as a potential screening mechanism for therapeutics. The tools and tests created in this project will be valuable for both Canadian and global ALS researchers as new resources to understand the disease and find new ways to treat it.
A research team led by Dr. Janice Robertson of University of Toronto has been awarded $1.6 million to understand whether the most common genetic abnormality in ALS, which occurs in the C90RF72 gene, causes or contributes to the disease through a loss of the gene's normal biological function. The majority of the research community is focusing on how the genetic abnormality in C9ORF72 might lead to an extra, toxic function, but in this five-year study, the team – which includes other collaborators at the University of Toronto as well as Sunnybrook Health Sciences Centre, McGill University and the Montreal Neurological Institute, and the University of British Columbia – will comprehensively analyze the potential damage to motor neurons lacking C9ORF72, and examine if both loss and gain of function mechanisms combine to cause ALS. This knowledge could fundamentally alter how therapeutics are developed for common forms of ALS as well as frontotemporal dementia (FTD), which often occurs with ALS.
Other projects that have been awarded $100,000 each in funding are:
Dr. Gary Armstrong at the Montreal Neurological Institute and McGill University is using a state-of-the-art technique in genetic manipulation to create new zebrafish models of ALS for the most prominent genetic cause of the disease, which relates to mutations in the C9ORF72 gene.
Dr. Neil Cashman at the University of British Columbia is using a unique fruit fly model to study whether a key toxic ALS protein can leap between neurons to explain spread of disease throughout the body.
Dr. Charles Krieger at Simon Fraser University is studying a substance called adducin that is critically linked to health at the site of connection between motor neurons and muscle, in order to understand whether this substance might represent a target for treatment to slow the progression of ALS.
Dr. Éric Lécuyer at Université de Montréal is using a unique set of scientific tools to comprehensively analyze the contents of key structures in ALS called stress granules.
Dr. Marlene Oeffinger at the Institut de recherches cliniques de Montréal is studying structures called paraspeckles to understand their content and how they function, as well as how they are altered in neuronal cells that have ALS-causing mutations.
Dr. Alex Parker at the Université de Montreal is undertaking a study to understand how probiotics slow down the progression of ALS symptoms in worms.
Dr. Lisa Topolnik at the Centre Hospitalier de l'Université Laval will study how certain neurons called interneurons, which connect to motor neurons in the brain, might be implicated in the early stages of ALS.
All of the research projects were selected through a competitive peer review process, regarded as the international benchmark of excellence in assessing projects for research funding. The peer review process engages a panel of international experts in ALS and other neurodegenerative diseases in evaluating and ranking all proposed research projects based on their scientific merit and on the potential to most quickly advance the field of ALS research in order to develop effective treatments. All aspects of the peer review process are executed in full partnership with Brain Canada, whose funds are provided through a partnership with Health Canada known as the Canada Brain Research Fund.
Approximately 1,000 Canadians are diagnosed with ALS each year. At any time, there are approximately 2,500 to 3,000 people living with the disease in Canada, and the average cost of caring for one person with ALS is between $150,000 and $250,000. Every day, two to three Canadians will die of ALS.
About Canada's ALS Societies ALS Societies across Canada fundraise on a regional basis to provide services and support to people and families living with ALS and to contribute to the funding of the ALS Canada Research Program. The ALS Canada Research Program funds peer-reviewed research grants and fosters collaboration amongst Canadian researchers, helping to nurture new ideas and build capacity. ALS Societies advocate federally, provincially and locally on behalf of people and families living with ALS for better government support and access within the healthcare system.
About Brain Canada and the Canada Brain Research Fund
Brain Canada is a national non-profit organization headquartered in Montreal, Quebec, that enables and supports excellent, innovative, paradigm-changing brain research in Canada. For more than one decade, Brain Canada has made the case for the brain as a single, complex system with commonalities across the range of neurological disorders, mental illnesses and addictions, brain and spinal cord injuries. Looking at the brain as one system has underscored the need for increased collaboration across disciplines and institutions, and a smarter way to invest in brain research that is focused on outcomes that will benefit patients and families. Brain Canada's vision is to understand the brain, in health and illness, to improve lives and achieve societal impact.
The Canada Brain Research Fund is a public-private partnership between the Government of Canada and Brain Canada, designed to encourage Canadians to increase their support of brain research, and maximize the impact and efficiency of those investments. Brain Canada and its partners have committed to raising $120 million, which is being matched by Health Canada on a 1:1 basis for a total of $240 million. For more information, visit www.braincanada.ca.
SOURCE ALS Canada
EMILY MALE WANTS YOU TO HAVE YOURSELF
A FOODIE FITTIE CHRISTMAS
Gearing up to Roll Out Her Exciting New 21 Day Program
That's "A Journey To The Best You," The 16 Year Old
Health and Wellness Authority Offers Insightful Tips
To Deal With Holiday Eating Temptations and Depression
Emily Male, founder of Foodie Fittie
On a mission to help her fellow teens to overcome their low self-esteem and find a pathway towards good nutrition, fitness, confidence and hope, Emily Male is currently gearing up for the early 2017 rollout of FoodieFittie (www.foodiefittie.com), her extraordinary, multi-faceted new 21 Day program which she designed as a "Journey To The Best You."
But before all the excitement begins with that, the Georgia and Nashvillebased 16 year old health and wellness authority is looking forward to a wonderful holiday season with family and friends. Because of her incredible personal journey - including a dramatic 78 pound weight loss in a single year and a renewed commitment to healthy eating, staying physically fit - Emily has some great insights and tips on how to eat right, overcome those bad temptations when it comes to overeating and fatty and sugary foods and avoiding depression this holiday season.
Based on her experiences and the knowledge she has gained as she worked on her program, she believes that eating the proper foods while not denying oneself the pleasure of reasonable portions of the cookies, cakes and pies you want can go a long way towards combating the winter blues. She will make her choices this year based on what worked for her during the holidays in 2015.
"Last Christmas," she says, "I made healthier choices, like instead of eating high fat meat, I ate low fat turkey - but I still ate dessert. If I knew I wanted that dessert, during the main meal I would avoid eating mashed potatoes. Even though the temptation is there to gorge yourself because tasty things are hitting your eyes everywhere you look, I think moderation is the key. Still, it's the holidays and if you restrict yourself too much it might be hard on keeping a jolly holiday spirit!"
Emily adds that while she doesn't eat an unlimited amount of goodies anymore, she has given herself some restrictions. "We all have to do what works best for us," she says. "I work hard all year long to maintain a certain weight and stay fit, and I'm not going to NOT eat something during the holidays just because it's got low nutritional value. Holiday time with our friends and family is important, and food is part of those gatherings. I would avoid excessive snacking but allow yourself a small portion of dessert. And keep this in mind: even if on a few days you consume extra calories, your body will know what to do with it. If you eat badly for two days, but then on the third day go back to eating your normal amount and consuming your usual amount of calories, your body will drop the few pounds it may gain."
Emily is currently in training for a body building competition this coming February, so she's watching her sugar and fat intake this holiday season. But make no mistake, she won't deprive herself of a few decadent treats. She also advises that when you know you're going to eat a huge meal later in the day, like on Thanksgiving, it's a good idea to eat normally during the early part of the day. Starving yourself for hours until mealtime is a guaranteed ticket to overstuffing yourself later, which can make you gain weight and get sick.
"When you understand the FoodieFittie lifestyle, you know when to stop indulging and get back to the nutritional program that makes you healthy," she says. "Maybe it would make me happy in the moment to go crazy and eat more than one cupcake or piece of cake after dinner, but afterwards - you guessed it - I would feel bad. But if I allow myself to just have one, I won't feel bad about any of it, physically or psychologically. I always look at the big picture."
One of the days in Emily's FoodieFittie program is devoted to depression, and Emily chronicles the painstaking route she took out of some very dark places inside her. Now that she's on the other side of things, and wakes up every day full of joy and determination to live a better, healthier life, she is happy to offer a few bits of advice to make yourself feel better during the holidays (but if you have diagnosed chemical depression, that is something beyond the scope of her expertise).
"My message is pretty simple even if getting here isn't easy sometimes: love yourself," she says. "There are so many little things you can do during the holidays to combat whatever blues you are feeling. You can give yourself a facial, read a book you love, go for a walk, go to the gym, do yoga, watch a great movie, listen to music, write things you are grateful for in a journal..Any of those things are good. My story is that I say I ran myself out of depression. I learned that molecular biologists and neurologists have begun to show that exercise may alter brain chemistry in much the same way that antidepressant drugs do -- regulating the key neurotransmitters serotonin and norepinephrine. So even if you live in a cold climate and have to do it inside, get moving and you'll experience some surprising results! The one thing you cannot do when you're depressed is sit around the house thinking of how depressed you are. That will start a downward spiral."
Because her oldest brother Ryan has been battling drug addiction for many years, Emily is keenly aware of the toll family tensions can take on the holiday season. Family meals can be uncomfortable for some, but Emily says it's best not to blame yourself for things outside your control and to simply "take relationships with your loved ones one day at a time." She adds: "I might have been sad to see my parents fight or feel like I was losing my brother because of what he was going through, but I got through some hard times simply by doing what I had to do, like going to school, doing chores, working and living life normally in spite of the problems. You have to live your life no matter what troubles are going on."
Happily, Emily is looking forward this holiday season to spending time with her family and her grandparents, who will be visiting from Florida along with her visiting brothers Ryan and Max. "It will be nice having everyone together," she says. "Everyone knows I love to cook, and I'll have the opportunity to make cheesecake and chocolate fudge cake, buffalo cheese dip and a bunch of other things - which I will eat in moderation of course! Cooking is another thing I find very therapeutic and when in doubt, that always makes my spirits bright around the holidays."
Having survived the trauma of being bullied, feeling lost and feeling sluggish and fearful of being mocked because of her extra weight, Emily's FoodieFittie program reflects her longtime desire to let her fellow teens (and others) in on many of the insights she's learned and put into practice that completely transformed her life. With the help of various mentors and fitness, nutrition and self-help experts, she created a detailed step by step process designed to change the lives of her peers.
"For the first time in my life," she says, "I'm on a mission, and that mission is a pathway to hope, a way for teens like me to make a comeback in their lives. I started FoodieFittie to help teen girls struggling with their weight and self-image, to help them feel more confident in who they are. From all of the challenges I have faced, I have learned that if you take control of your dieting habits and are consistent with your fitness activities, you will have great results."
United Breast Cancer Foundation (UBCF) Releases New #FlauntYourFight Public Service Announcement in NYC’s Times Square PSA focusing on body positivity in breast cancer patients and survivors
The United Breast Cancer Foundation (UBCF) follows their recent PSA campaign on the importance of early breast cancer detection with the empowering PSA, #FlauntYourFight airing in New York City’s Times Square. The PSA is a call to action for all breast cancer patients and survivors to be proud of their bodies, their struggles, and their journeys in the fight against the disease. The provocative imagery of women dressed as warriors is airing on a full HD billboard located prominently at 1500 Broadway now through January 5, 2017. The 10 second ad that runs 3 times an hour, 20 hours a day, relays a visual message of UBCF’s goal to relieve the stresses of all those who are affected by breast cancer. Neutron Media assisted with creative production.
The images were first seen in a UBCF-sponsored art show, “The Faces of Breast Cancer,” by Frenchphotographer Pascal Latil, in August 2015. Women may face psychological stress for remaining vigilant intheir appearance after losing either their breasts or hair. The #FlauntYourFight campaign gives a voice to manyclients served at UBCF and far beyond. Stephanie Mastroianni, UBCF President and Executive Director, says, “Our hope is to continue to debunk the stereotype of beauty and what defines a woman and her femininity.” Mastroianni continued, “This is milestone for UBCF; [continuing] a branding opportunity in Times Square,which is truly the center of the world. Over 26 million people visit Times Square every year – that’s nearly 50,000 per day seeing UBCF's #FlauntYourFight PSA.”
Maintaining a normal lifestyle can be the most comforting service provided by UBCF programs. This new messaging is intended to empower breast cancer patients and survivors to be proactive about treatment and aftercare. UBCF’s seven programs offer financial and emotional support, as well as a comprehensive approach to managing many aspects of living with cancer. About Neutron Media
Neutron Media, Inc. has thrived for fourteen years by providing outstanding customer service and introducing business and non-profit organizations to the exciting, far-reaching possibilities of advertising through LED Outdoor Media. Neutron Media’s current jewel in the crown is the stunning HD screen at the corner 1500 Broadway and West 43rd Street, in the heart of Times Square in New York City. http://www.neutronmedia.com About UBCF
UBCF is committed to offering breast health and wellness services focused on cancer prevention, screening, treatment and over-all wellness. UBCF’s mission, to make a positive difference in the lives of those affected by breast cancer, is carried out every day through seven life-supporting patient and family programs available to women, men and families nation-wide. UBCF never denies services to anyone regardless of age, race, gender, ethnicity, income or medical insurance coverage. If you are in need of breast health services, please visit UBCF at http://www.ubcf.org or call toll-free, 877-822-4287. Tax-deductible contributions may be made towards UBCF’s programs. UBCF accepts vehicle and property donations as well. Contributions may be mailed to UBCF, P.O. Box 2421, Huntington, NY 11743, or donate through the Combined Federal Campaign, #77934.
ROBERT F. KENNEDY, JR. LAUNCHES THE WORLD MERCURY PROJECT Vows to change government policies that injure children.
Washington, DC—Robert F. Kennedy, Jr. announced today the launch of the World Mercury Project (WMP), a public health advocacy organization dedicated to ending exposure to neurotoxic mercury in fish, medical products, dental amalgams and vaccines. The group will focus on making sound science the driver of public policy.
“We will expose the government and corporate corruption that has led to increasing exposures to neurotoxic mercury in foods and medicines,” said Lyn Redwood, RN, MSN, the group’s executive director.
WMP joins these organizations calling for the repeal or radical reform of NCVIA. “This act provided vaccine manufacturers blanket immunity for any harm caused by injuries from vaccines, no matter how wanton, reckless or negligent the manufacturing, how anemic the testing or how grievous the injury,” Kennedy said. “That act and the mountains of pharma cash going to politicians, regulators and the press have helped obliterate all the checks and balances that normally stand between a rapacious industry and vulnerable children in a free and Democratic society. The complete vacuum of accountability caused by the NCVIA has emboldened the worst kind of behavior by vaccine makers including the continued use of mercury in vaccines.”
“We want robust and transparent science, independent and honest regulators, safe vaccines and healthy children,” Kennedy added. “Although Congress intended this law to make children healthier and safer, it has paradoxically made them less healthy and less safe, allowing them to receive mercury-contaminated vaccines that other countries have long outlawed.”
ExamOne joins Manulife Vitality to provide free annual wellness checkup
"Vitality Check" provides another opportunity to earn Vitality Points
Manulife today announced that ExamOne has joined the Manulife Vitality program as a provider of Vitality Check, a physical fitness checkup for Manulife Vitality members. The goal of this free service is to give members an update on their general health and health risks. Manulife Vitality members who choose to participate in this optional service will also earn Vitality Points toward their Vitality Status, which can lead to rewards including discounts on their life insurance premiums.
Manulife Vitality members choosing to have a Vitality Check can do so through their preferred health provider (accredited medical practitioner/doctor) or by ExamOne, in a location of the member's choice.
"Vitality Check provides an additional level of insight into one's overall health," said Blake Hill, Head of the Manulife Vitality program. "Not all provincial health care systems cover the requirements and cost of a health review equivalent to Vitality Check so we have joined with ExamOne to provide it free of charge to Manulife Vitality members."
Vitality Check includes a collection and reporting of members' blood pressure, glucose, cholesterol and body mass index, and provides members with personal health information they can use to better understand their overall health and to make informed choices about their health care. Manulife Vitality rewards members with Vitality Points for simply choosing to complete a Vitality Check and learning about their health. Members can be further recognized with additional Vitality Points if their biometric measures are within healthy ranges.
Members connect with ExamOne through the Manulife Vitality secure member website, and will be connected with a local paramedical professional. The ExamOne representative will arrange for the checkup in a location of the member's choice, including their home or workplace. Results are only provided to the member and to The Vitality Group Inc., the administrator of the program in order to award the Vitality Points.
Manulife Vitality is a whole new approach to life insurance. It is a personalized wellness program that offers rewards when you make choices to live a healthier life. You can accumulate Vitality Points for routine activities you may already be doing to stay healthy. With Manulife Vitality, your life insurance has the potential to save you money and reward you for living a healthier life. Members of the Manulife Vitality program earn Vitality Points when they complete healthy living activities, such as health education courses, exercising, getting an annual health checkup, or even a flu shot. The number of Vitality Points a member accumulates over the course of a year determines their Vitality Status level. The greater the status that the member attains in the Manulife Vitality program the more they can enjoy the program rewards and benefits.
About Manulife Manulife Financial Corporation is a leading international financial services group providing forward-thinking solutions to help people with their big financial decisions. We operate as John Hancock in the United States, and Manulife elsewhere. We provide financial advice, insurance and wealth and asset management solutions for individuals, groups and institutions. At the end of 2015, we had approximately 34,000 employees, 63,000 agents, and thousands of distribution partners, serving 20 million customers. At the end of September 2016, we had $966 billion (US$736 billion) in assets under management and administration, and in the previous 12 months we made more than $24.4 billion in benefits, interest and other payments to our customers. Our principal operations are in Asia, Canada and the United States where we have served customers for more than 100 years. With our global headquarters in Toronto, Canada, we trade as 'MFC' on the Toronto, New York, and the Philippine stock exchanges and under '945' in Hong Kong. Follow Manulife on Twitter @ManulifeNews or visit manulife.com or johnhancock.com.
About Vitality The Vitality Group is a member of Discovery Ltd., a global financial services organization offering an incentive-based health and well-being program to employers, as part of their benefits program, and to insurers. With a foundation based on actuarial science and behavioral economic theory, Vitality encourages changes in lifestyle that reduce healthcare costs, both in the short run and long term, by rewarding members for addressing their specific health issues. Vitality well-being programs serve companies in a wide range of sizes and industries, improving individuals' health and wellbeing as well as employers' bottom lines.
Vitality brings a global perspective through successful partnerships with large employers and best-in-class insurers around the world, in countries including the United States, United Kingdom, South Africa, China, Singapore, Australia, Hong Kong, and the Philippines. Additional information can be found at thevitalitygroup.com.
Medtronic the first to offer complete portfolio of full-body MR conditional neurostimulation systems for chronic pain in Canada
Medtronic SpecifyTM SureScanTM MRI Surgical Leads Rounds Out Exclusive Portfolio Designed for Access to Full-Body MRI*
BRAMPTON, ON, Nov. 8, 2016 /CNW/ - Medtronic Canada, a subsidiary of Medtronic plc (NYSE:MDT), announced the Health Canada licence and the first Canadian implants of the new Specify™ SureScan™ MRI surgical leads, which are indicated for use as part of Medtronic's implanted neurostimulation systems (also known as spinal cord stimulation, or SCS) for chronic pain. In 2013, Medtronic introduced the first implantable neurostimulation systems for use in the treatment of chronic, intractable back and/or limb pain that are licenced for full-body Magnetic Resonance Imaging (MRI) scans under specified conditions. The licencing of Specify SureScan MRI surgical leads establishes Medtronic as the only company in Canada with a full portfolio of SCS systems licenced by Health Canada for full-body MRI.* This means physicians in Canada can now offer a Medtronic full-body MR Conditional SCS system best suited for their patients regardless of the type of neurostimulator (rechargeable or non-rechargeable) or lead type (percutaneous or surgical).
"The majority of patients implanted with SCS devices will need MRI studies in the future, and until now they have either undergone other more invasive examinations or had the SCS device explanted. Physicians and patients can now approach this therapy with the confidence that their ability to access future diagnostic procedures won't be lost. This innovation has raised the bar in the delivery of neuromodulation for treatment-refractory neuropathic pain" said Dr. Mohammed F. Shamji MD, PhD, FRCSC, neurosurgeon at the Krembil Neuroscience Centre at Toronto Western Hospital.
"An important development in the field of neuromodulation is the availability of MRI conditional devices. These devices allow for patients to undergo routine MRIs and continue to benefit from neuromodulation therapy - a previously unmet need for many of our patients. Our team is pleased that we can now offer this technology as a potential treatment option." said Dr. Suneil Kalia, MD, PhD, FRCSC, neurosurgeon at the Krembil Neuroscience Centre at Toronto Western Hospital.
Back pain is estimated to affect 8 out of 10 people at some point during their lives.1 For some people, noninvasive options, such as medication and physical therapy, provide adequate relief; others may require surgery, nerve blocks, or medical devices, such as spinal cord stimulators or drug pumps. Spinal cord stimulators are medical devices implanted under the skin that send mild electrical pulses to an area near the spine. These pulses disrupt the pain signals traveling between the spinal cord and the brain, offering patients effective pain relief and improved function.2
"The use of MRI as a diagnostic tool has grown significantly. Studies show that 82 percent of patients implanted with a SCS are expected to need an MRI within five years of receiving their implant.3 Medtronic appreciates the opportunity to offer physicians the only full portfolio of SCS systems in Canada that allow patients access to full-body MRIs, facilitating optimal patient care and timely interventions," said Sandrine Moirez, senior business director of the Restorative Therapies Group at Medtronic Canada. "Medtronic remains committed to the advancement of spinal cord stimulation therapy overall and continues to drive technological advancements to ensure greater access to MRIs across many of our implanted Medtronic systems, such as pacemakers, ICDs and deep brain stimulation systems."
While the benefits of neurostimulation therapy are well documented, some individuals with an SCS system have traditionally been limited when receiving MRI scans, as the scans produce electromagnetic fields that can damage the device or cause injury to the patient. These patients have the option of undergoing computerized tomography (CT) scans, which work well for imaging bones and other hard materials, but are less effective in examining soft tissue. In some cases, people needing an MRI have had the system explanted prior to imaging.
Additional benefits of the Medtronic Spinal Cord Stimulation Therapy include:
Technology that is proven to significantly relieve pain for the long term4 and help patients get back to the everyday activities they enjoy.2
The opportunity for patients to "test drive" spinal cord stimulation with an external stimulator for a 3 to 10 day trial period during which they can assess how well the therapy relieves their pain during daily activities before committing to long-term therapy.
RestoreSensor™ SureScan MRI systems feature Medtronic's AdaptiveStim™ technology, which adjusts stimulation automatically. Patients no longer have to use their programmer to make manual adjustments every time they change position.
Personalization that empowers patients to manage their own pain therapy by adjusting their stimulation within pre-set limits.
About Medtronic Medtronic Canada (www.medtronic.ca), headquartered in Brampton, Ontario is a subsidiary of Medtronic plc, which is among the world's largest medical technology, services and solutions companies — alleviating pain, restoring health and extending life for millions of people around the world. Medtronic is proud to employ over 1,600 people in Canada, serving physicians, hospitals and patients across the country. The company is focused on collaborating with stakeholders around the world to take healthcare Further, Together.
Any forward-looking statements are subject to risks and uncertainties such as those described in Medtronic's periodic reports on file with the Securities and Exchange Commission. Actual results may differ materially from anticipated results.
References 1 Web site: https://www.nlm.nih.gov/medlineplus/backpain.html Accessed: February 10, 2016 2 Kumar K, Taylor RS, Jacques L, et al. Spinal cord stimulation versus conventional medical management for neuropathic pain: a multicentre randomized controlled trial in patients with failed back surgery syndrome. Pain. 2007;132:179-188. 3 Desai MJ, Hargens LM, Breitenfeldt MD, Doth AH, Ryan MP, Gunnarsson C, Safriel Y. The rate of magnetic resonance imaging in patients with spinal cord stimulation. Spine. 2015 May 1;40(9):E531-. 4 Kumar K, Taylor RS, Jacques L, et al. The effects of spinal cord stimulation in neuropathic pain are sustained: a 24-month follow-up of the prospective randomized controlled multicenter trial of the effectiveness of spinal cord stimulation. Neurosurgery. 2008;63(4):762-770. * Under specific conditions. Refer to Instructions for Use.
SOURCE Medtronic of Canada, Ltd.
Life Financial and Toronto Rehab Foundation to make an exciting announcement improving wellness around the globe through innovative diabetes prevention and management program
TORONTO, Nov. 9, 2016 /CNW/ - Sun Life Financial and the Toronto Rehab Foundation will be making an exciting donation and announcement about improving wellness around the globe through better diabetes prevention and management. This innovative program will extend diabetes care beyond hospital walls and empower individuals living with the disease to take control of their health, regardless of barriers such as geography, financial constraints and language. Hockey Hall of Famer Darryl Sittler and former NHL player Brandon (BJ) Crombeen will be on-hand to help launch this exciting new initiative.
Darryl Sittler, former NHL Player and Hockey Hall of Famer
Brandon (BJ) Crombeen, former NHL Player
Lisa Ritchie, Senior Vice-President & Chief Marketing Officer, Sun Life Financial
Dr. Peter Pisters, President & CEO, University Health Network
Dr. Paul Oh, Medical Director, Cardiac Prevention & Rehabilitation Program, TRI-UHN
Space is limited - members of the media are requested to RSVP to Alessandra Nigro at alessandra.nigro@sunlife.com.
About Sun Life Financial Sun Life Financial is a leading international financial services organization providing a diverse range of protection and wealth products and services to individuals and corporate customers. Sun Life Financial has operations in a number of markets worldwide, including Canada, the United States, the United Kingdom, Ireland, Hong Kong, the Philippines, Japan, Indonesia, India, China, Australia, Singapore, Vietnam, Malaysia and Bermuda. As of June 30, 2016, the Sun Life Financial group of companies had total assets under management of $865 billion. For more information please visit www.sunlife.com.
Sun Life Financial Inc. trades on the Toronto (TSX), New York (NYSE) and Philippine (PSE) stock exchanges under the ticker symbol SLF.
About Toronto Rehabilitation Institute As the world-leading rehabilitation research centre, Toronto Rehabilitation Institute is revolutionizing rehabilitation by helping people overcome the challenges of disabling injury, illness or age related health conditions to live active, healthier, more independent lives. It integrates innovative patient care, ground breaking research and diverse education to build healthier communities and advance the role of rehabilitation in the health system. Toronto Rehab, along with Toronto General and Toronto Western Hospitals, the Princess Margaret Cancer Centre and The Michener Institute for Education at UHN is a member of the University Health Network and is affiliated with the University of Toronto. www.uhn.ca.
When most people think of Botox the first thing that usually comes to mind is wrinkle reduction. Indeed, Botox is the world’s most popular treatment for eradicating wrinkles and fine lines. The toxin is specifically FDA approved for treating frown lines between the eyebrows (glabellar lines) and lines around the eyes (crow’s feet). In addition to being the gold standard for wrinkle reduction, Botox can also be used to treat a variety of issues, both cosmetic and non-cosmetic. Dr. John Zannis is a New Bern, North Carolina board certified plastic surgeon. He provides a list of conditions that Botox has been used to treat.
Acne
Botox can curb oil production, reducing breakouts. "To totally treat acne, you'd need to use doses of Botox so large they'd prevent you from constricting your facial muscles," says Dr. Zannis. "But tiny amounts of Botox injected very superficially help reduce oil production, and you can still have facial expressions." Though he'd recommend it for almost any patient struggling with acne, Zannis would likely advise trying another dermatologist-prescribed treatment, like spironolactone or birth control pills, first. And though it can technically be used to quell oil production anywhere on the face, he cautions against using it all over because of potential effects on muscular activity (a.k.a. frozen face). The most effective and common area for using Botox to curb oil production, he says, is the forehead.
Gummy smile (not FDA approved)
A "gummy" smile, one that's characterized by a smile that shows too much of the gums, usually results from "excessive lip elevation" when the upper lip rises too far above the upper teeth when smiling. Injecting Botox into the upper lip weakens the upper lip's retractor muscles so that it won't raise as high and your smile will seem better-balanced. It can be done in about five minutes. Usually lasts for four to six months. Costs range from $200-$300. Dr. Zannis says, "This technique is not for the novice Botox injector. Too much, and your lip won’t raise enough, too little and you will need more, or if injected asymmetrically, you might have a funny asymmetrical smile."
Urinary incontinence.
Overactive bladder problems affect up to 20% of women over 40. For severe cases where medications do not provide complete relief, Botox injections into the bladder wall may provide relief lasting about 6 months.
Psoriasis
Psoriasis is uncomfortable, itchy, and not exactly easy on the eyes. Luckily, this flaky skin condition could be a thing of the past thanks to Botox. Though psoriasis is technically incurable, Botox minimizes the activity of inflammatory cells that bring on outbreaks.
Excessive Sweating
For those who suffer from excessive sweating, however, summer isn’t always the sunniest time of the year. Thankfully, Botox could be a saving grace for those attempting to manage this condition, which is officially known as axillary hyperhidrosis. Studies show that just a handful of injections can reduce underarm sweat for up to TWO years. Um, where do we sign up?
Breast Lift
Are your breasts in need of a pick-me-up? Instead of going under the knife and getting permanent augmentation, some experts have suggested a quick and easy Botox lift. Dr. Zannis says that, “Those looking for a modest improvement are said to be able to temporarily plump their assets thanks to injections into the pectoralis minor chest muscle.”
Depression
The benefits of Botox® may be more than skin deep; two recent studies suggest that it may help alleviate the symptoms of depression. In a study published in the May 2014 issue of the Journal of Psychiatric Research, more than half of participants who had moderate-to-severe depression showed a substantial improvement in depressive symptoms following one injection of Botox® between the brows. This improvement lasts longer than the cosmetic effects, suggesting that the effect may be more than just feeling better about your appearance. Botox® is not approved to treat depression.
Teeth Grinding
Injections of Botox® were used to control involuntary muscle tension and spasms long before it became the go-to wrinkle buster. Dr. Zannis says that, “these neurotoxin injections may weaken the chewing muscles enough to reduce bruxism (teeth grinding) without affecting your ability to chew, talk and smile. Results last about four months. Botox® is not yet approved to treat bruxism.”
Migraine Headache
Botox® is approved by the FDA to treat chronic migraine headaches in adults who have 15 or more headache-days a month, each lasting four hours or more. Studies that led to this indication show that BOTOX®® prevents up to nine headache-days a month (vs seven for dummy injections). Other research hints that the neurotoxin may also help with low cerebrospinal fluid headaches and cluster or "suicide" headaches.
Brow Boost
Much like lines form over time, your brow may also drop or droop. Botox cosmetic treatments can also be used to improve the appearance of the brow. Dr. Zannis explains that, “the treatment essentially freezes the sagging muscles in place and gives the brow more stability. Lifting the brows in this way leaves you with a less tired and younger, fresher appearance.”
Jaw Reduction (off label use)
Botox can be used to perform jaw reduction (commonly called jaw line softening). Injecting Botox into the masseter muscle (the primary muscle used in chewing actions) reduces its overall size; transforming an overly square and masculine appearing jawline into a more feminine oval or heart shape.
Dr. John Zannis is a New Bern, North Carolina board-certified plastic surgeon and best selling author. A graduate of Stanford University and The University of Cincinnati Medical College, he received his formal training in General Surgery and Plastic and Reconstructive Surgery at Wake Forest University in Winston-Salem, North Carolina under the guidance of world-renowned plastic surgeon Dr. Louis Argenta. During this time, he performed over 5,000 surgical procedures and covered all aspects of plastic surgery including cosmetic surgery of the face and body, complex reconstructive procedures of face and body, cleft lip and palate surgery, hand surgery, facial and jaw fracture repair, and reconstruction following massive weight loss. He blends his interests and studies of classical art and symmetry to his surgery practices. Connect with him via twitter@JohnZannisMDor his website www.zannisplasticsurgery.com
HAVE TROUBLE COPING WHEN THE CLOCKS “FALL BACK?”
YOU MAY HAVE SEASONAL AFFECTIVE DISORDER AKA.. SAD
The clocks “fall back” November 6, 2016 which means that there will be less day light. Many people chalk up feeling blue in winter as simply a fact of cold weather and lack of sunshine. But 4 to 6 percent of people may have a winter depression which is clinically referred to as Seasonal Affective Disorder. Another 10 to 20 percent may have mild SAD. SAD is four times more common in women than in men. Although some children and teenagers get SAD, it usually doesn't start in people younger than age 20. Your chance of getting SAD goes down as you get older.SAD is also more common the farther north you go. For example, it's seven times more common in Washington State than in Florida. Dr. Sanam Hafeez is a neuro-Psychologist in NYC (Manhattan and Forest Hills, Queens), and treats patients in her practice who display and express mood changes once October rolls around.
Dr. Hafeez explains that, “In most cases, seasonal affective disorder symptoms appear during late fall or early winter and go away during the sunnier days of spring and summer. However, some people with the opposite pattern have symptoms that begin in spring or summer. In either case, symptoms may start out mild and become more severe as the season progresses.”
The following are symptoms to look for to see if you are suffering from SAD
Depression
Hopelessness
Anxiety
Loss of energy
Heavy, "leaden" feeling in the arms or legs
Social withdrawal
Oversleeping
Loss of interest in activities you once enjoyed
Appetite changes, especially a craving for foods high in carbohydrates
Weight gain
Difficulty concentrating
How is SAD treated?
Many people with SAD will find that their symptoms respond to a very specific treatment called bright light therapy. For people who are not severely depressed and are unable—or unwilling—to use antidepressant medications, light therapy may be the best initial treatment option says Dr. Hafeez.
Light therapy consists of regular, daily exposure to a “light box,” which artificially simulates high-intensity sunlight. Practically, this means that a person will spend approximately 30 minutes sitting in front of this device shortly after they awaken in the morning. If patients do not improve, a second exposure of 20-30 minutes may be added in the early afternoon. Treatment usually continues from the time of year that a person’s symptoms begin, such as in fall, on a daily basis throughout the winter months. Because light boxes are created to provide a specific type of light, they are expensive and may not be covered by insurance. Unfortunately, having lots of lamps in one’s house and spending extra time outside is not as effective as this more expensive treatment.
Dr. Hafeez states that, “Side effects of light therapy are uncommon and usually reversible when the intensity of light therapy is decreased. The most commonly experienced side effects include irritability, eyestrain, headaches, nausea and fatigue.”
Scientific studies have shown light therapy to be very effective when compared to placebo and as effective as antidepressants in many cases of non-severe SAD. Light therapy may also work faster than antidepressants for some people with notable effects beginning with in a few days of starting treatment. Other people may find that it takes a few weeks for light therapy to work, which can also be the case for most people who take antidepressant medications. Although not explicitly recommended, some people may elect for treatment with both light therapy and antidepressant medications. The combination of these treatments may be synergistic and a more robust way to address the symptoms of SAD.
In her practice Dr. Hafeez has found that antidepressant medications have been useful in treating people with SAD. Of the antidepressants, fluoxetine (Prozac) and bupropion (Wellbutrin) have been studied in the treatment of SAD and shown to be effective. The U.S. Food and Drug Administration (FDA) has approved these medications for treatment of major depressive disorder. Dr. Hafeez cautions that, “Any person considering treatment with an antidepressant medication should discuss the benefits and risks of treatment with their doctors.”
Individuals with a predisposition to bipolar disorder should be more cautious in approaching treatment for SAD and depression in general. Light therapy, like antidepressant therapy has been associated with increased risk of experiencing a manic episode. The specifics of this are beyond the scope of this review and again, should be discussed with one’s doctors.
Finally, a healthy lifestyle, including regular exercise, a good diet and a strong social network, is also likely to help you cope with SAD.
Sanam Hafeez Psy.D
New York State Licensed Neuropsychologist and School Psychologist
Dr. Sanam Hafeez is a New York City based Neuropsychologist and School Psychologist. She is also the founder and director of Comprehensive Consultation Psychological Services, P.C. She is currently a teaching faculty member at Columbia University.
Dr. Hafeez graduated from Queens College, CUNY with a BA in psychology. She then went on to earn her Master of Science in Psychology at Hofstra University. Following that she stayed at Hofstra to receive her Doctor of Psychology (Psy.D.) She later completed her post-doctoral training in Neuropsychology and Developmental Pediatrics at Coney Island Hospital.
Dr. Hafeez’s provides neuropsychological educational and developmental evaluations in her practice. She also works with children and adults who suffer from post traumatic stress disorder (PTSD), learning disabilities, autism, attention and memory problems, trauma and brain injury, abuse, childhood development and psychopathology (bipolar, schizophrenia, depression, anxiety, etc…) In addition, Dr. Hafeez serves as a medical expert and expert witness by providing full evaluations and witness testimony to law firms and courts.
Dr. Hafeez immigrated to the United States from Pakistan when she was twelve years old. She is fluent in English, Urdu, Hindi and Punjabi (Pakistani and Indian languages.) She resides in Queens, New York with her husband and twin boys.
FinTech lender Health Smart Financial Services announces new senior credit facility with CWB Maxium Financial
Health Smart Financial Services ("Health Smart"), a technology-enabled specialty lender, announced today that it has closed a new senior revolving credit facility with CWB Maxium Financial ("CWB Maxium").
Health Smart's technology platform allows healthcare providers to offer their customers affordable monthly payments for services and products that require private out-of-pocket expense. Health Smart has a rapidly growing base of over 1500 merchant partners who benefit from the company's instant credit approval and paperless transaction capability.
"CWB Maxium is a great partner for our business," said Wayne Pommen, President & CEO of Health Smart. "This new revolving facility replaces our existing facilities and provides us with substantially increased funding capacity to grow our consumer loan portfolio. Combined with the growth equity investment we received from iA Financial Group last month, we are very well capitalized to continue our pace of growth in 2017 and beyond."
"We are pleased to be a funding partner for Health Smart as they capture the point-of-sale financing opportunity in Canada," said Neil Cruickshank, Vice President at CWB Maxium. "Health Smart has tremendous potential to attract quality financial assets. The transaction aligns with our strategy for creative and innovative financing, and supports our growing portfolio in the Canadian financing sector. We look forward to ongoing growth opportunities and collaboration."
About Health Smart: Health Smart Financial Services is a leading Canadian point-of-sale consumer lender focused primarily on the healthcare sector. Using Health Smart's platform, healthcare providers can have their customers approved for affordable monthly payments on-location or remotely using desktop, tablet, or smartphone interfaces. By partnering with Health Smart, merchants provide their customers with greater access to services while growing their sales. Health Smart's major segments include dentistry, fertility, audiology, mobility devices, veterinary services, and cosmetic procedures, in addition to selected segments outside the healthcare sector. Health Smart has approved over $170 million in consumer credit since inception.
About CWB Maxium: CWB Maxium Financial is a CWB Group company and offers creative structured financing that responds directly to the specific needs of each customer. Maxium Financial Services Inc. was founded in 1993, and on March 1, 2016, it became a CWB Group company. Today, the portfolio exceeds $1 billion. With over 35,000 customers, CWB Maxium is earning a reputation for innovative lending solutions coupled with an unparalleled ability to build long-term relationships. Learn more at www.cwbmaxium.com
TRAIN IT RIGHT NEWSLETTER
Sign Up and get a free 7 day Train it Right HIIT Program!
