Natural personal-care line founder, Shannon Drake shares the dirt on ingredients to watch out for in toothpaste to keep your pearly whites white, and your body safe from toxins 

Have you ever read the ingredients in your toothpaste? Scary right? Founder, chief beautifucication officer and lead dirty girl Shannon Drake will help guide you  through the top toothpaste ingredients to look out for: the good, the bad and the ugly! She developed this super-natural line The Dirt, only four years ago, and swaps out only all-natural ingredients completely natural and free of gluten, soy, corn and grain. Drake invented the first ever MCT (coconut oil) based toothpaste and top selling clay toothpowder, and has developed a cult following accross the country and beyond.
"I want to change our morning routine into a self care ritual. We are gifted these amazing human bodies for our short trip around the sun, when we take care of ourselves we are showing our appreciation for this amazing opportunity we are given. By changing our routines into a self care ritual we are fundamentally changing our experience of reality into one based around a pleasurable, luxurious, engaged human experience. As a long time practitioner of the paleo lifestyle I noticed  something about my favorite natural products... they were pretty lame. Many used ingredients that were highly processed, questionably safe and just seemed 'green washed'. I felt really let down," explains Drake, "Using the principals of the paleo lifestyle; a 'whole foods' life style based on clean eating and high nutrients I drew inspiration from my passion for studying traditional beauty secrets from around the world to craft high quality, beautiful and natural products for women, men and kids too."

Here is the good, the bad, and the ugly on toothpaste and what to look out for:

The Good

Coconut Oil - Everyone’s favorite oil, it is anti-bacterial, anti-viral and helps to balance and moisturize the delicate skin on the mouth protecting against sores and dry mouth.

Bentonite Clay - An amazing edible clay that has been used to detoxify the body for hundreds of years!, It is a mild abrasive and is gentle on teeth.

Myrrh - Used since ancient times to heal and protect the gums, it is Anti-bacterial and naturally heals wounds and sores of the mouth like canker sores.

Clove - Is a natural toothache aide, a little bit of close will not only numb tooth pain but also helps to fight any infection that may be causing the pain.

The Bad

Artificial sweetener - Aspartame, saccharin, Sucralose, mother nature didn’t make these and you should avoid them in your toothpaste. They are associated with many chronic diseases like shrinkage of the thymus gland, reduced growth rate, dementia, some cancers and immune diseases. These sweeteners are in a lot of processed foods so many people already get a high dose of these sweeteners. They are easily avoided in toothpaste.

Artificial preservatives - Artificial preservatives can cause inflammation in some individuals, also some people have bad reactions to preservatives and may get dry chapped lips or break outs from these preservatives touching their lips during brushing.

The Ugly

Plastic Microbeads - Plastic is ruining our planet and while it may be hard to avoid completely it is easily avoided as an ingredient in toothpaste. sparkly bits, flecks or white dots clue you into plastic micro beads in your paste. Not only do these tiny beads get into our water system and poison fish but they also can wedge themselves in-between your teeth and gums, opening up space where bacteria can plaque can settle.

Propylene glycol -  When derived from petroleum Propylene glycol is an artificial substance the is not optimal for your system.

Triclosan - Used as an anti-bacterial agent triclosan kills not only the bad bacteria but also the good bacteria in your mouth. It also gets into the water system and kills microscopic organisms that are essential to the eco system. It was developed to be a pesticide and has been tied to endocrine disruption, thyroid disorders and one study showed it gave mice fetal bone disorder. People who use Triclosan toothpastes have been shown to have it in their urine, proving that although we spit out our toothpaste, the chemical ingredients still get into our system.

Click here to see our video with Shannon explaining the good, the bad and the ugly on toothpaste

Shannon's natural must-have solutions to keep your mouth minty fresh, teeth pearly white 

Oil Pulling Mouthwash - $40

Why yes, you read that right - this excellent elixir is both an oil pull and a mouthwash. Fancy a fix of fresh breath? Gargle a gulp for a stint to fend off the funk with clove and mint. On a quest to invest in your oral best? Savor a swig with glee to exile toxins with clove and sesame. So whether you need to rally for a stroll down makeout alley, or embark on a trek to dislodge bacterial drek, our Oil Pulling Mouthwash has that secret sauce that'll keep you saying 'dang, this stuff is BAWSE!'

MCT Oil Toothpaste - $10/$15/$30

The Dirt's MCT Oil Toothpaste, an effective and tasty alternative to synthetic oral care, is a small but mighty. The MCT Oil Toothpaste improves oral health through the use powerful, natural ingredients while building a unique flavour profile. For lovers of the classic toothpaste taste, Rose Cocoa Mint features a strong mint flavour.  Looking for a milder flavour? Give Sweet Cinnamon a try. Last but not least, Cocoa Mint boasts the unique flavour of both bold mint and sweet chocolate.

Dirty Balm Lip Treatment - $10

Can't get enough of the lip balm? The Dirt has got you covered with their Dirty Balm! You've tried every lip balm on the market but you're about to meet your match. The Dirt's lip balm uses traditional beauty secrets from around the world to provide the most effective lip care you have ever tried. This is the BEST lip balm on the PLANET!

Trace Mineral Tooth Brushing Powder - $30

Voted top tech beauty product of 2016 by Instyle on the Today Show,  give mom the  The Dirt's original and best spiced trace mineral tooth brushing powder! Did you know the glycerin in modern toothpaste can coat your teeth and prevent the natural process of re-mineralization that keeps your teeth strong and white? The Dirt is made to support your natural re-mineralization process and get your teeth back to their strong, sparkly selves. It has a sweet spiced orange flavour that will leave your mouth feeling clean and spicy!

Anti-Microbial Copper Tongue Scraper - $10

Give the gift of fresh breath with The Dirt's Copper Tongue Scraper. The Copper Tongue Scraper removes the gunk that brushing alone simply cannot. Why copper? Various forms of copper have been used for medicinal purposes throughout the history of mankind, the Egyptians used copper for their water pipes, ship builders used copper to keep algae off ships, copper has recently been tested in the fight against the deadly MRSA virus.

Clean Mint or Sweet Cinnamon Natural Breath Spray - $10

Looking for an all natural breath spray free of alcohol, artificial flavoring, GMO glycerine or xylitol? The Dirt has the answer for you! Their Breath Sprays use only MCT Coconut oil, therapeutic grade essential oils, and solvent free stevia extract to give you that fresh minty breath you crave, plus a pick me up of healthy essential fatty acids. What other breath spray can do that?  And in honour of Earth Day, their 1oz amber glass bottle keeps your spray fresh while looking sleek and reducing the use of plastic. Recycle the bottle or re-purpose.

Pair with their Toothpowder or MCT Coconut Oil Toothpaste for fresh breath that can't be beat!

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About The Dirt: The Dirt Paleo Personal Care was founded to start a revolution. We were not satisfied with the natural product lines on the market, many a 'green washed' to look much safer than they actually are and most use soy or corn byproducts which are cheap and unnecessary fillers. We demand more!  We invented the first ever MCT (coconut oil) based toothpaste and top selling clay toothpowder, and has developed a cult following accross the country and beyond.

All of our products are Soy Free, Corn Free, Gluten Free, Grain Free, Cruelty Free and Natural. We don't use fillers, ever! Our essential oil blends are formulated to preform not just smell good (Sorry other guys). Everything about our product blends is intentional... and awesome.

Because, why should your healthy lifestyle stop at your plate? Fix your face! The dirt is 100% natural 200% kick-ass.

The line has been featured in many media outlets including InStyle, Vogue,  LouLou, Flare, Well+Good, Beauty Editor, The Kit, and The Today Show. Shannon is a great resource both on and off camera and is available for sound-bites or or interviews.

About Shannon Drake, owner and founder: I've been a long time practitioner of the paleo lifestyle. After sticking to an extremely healthy routine, I started to notice something about my favorite natural products... They kinda sucked. I felt let down, many used ingredients that were highly processed, questionably safe and just seemed 'green washed'.

Using the principals of the paleo lifestyle; a 'whole foods' lifestyle, clean eating and high nutrients I drew inspiration from my passion for studying traditional beauty secrets from around the world. I blended potion after potion until the ultimate formulas were created. 'The Dirt' Paleo Personal Care was born.

Ingredients: We're taking 'natural' to the next level. Our blends are made using the highest quality natural ingredients and they are also specially formulated to work with your body in very specific ways. We use essential oils for their healing properties, absolutes for their aromatherapy properties and oils and butters for their nutrients. While you may love a mint lip balm we would not recommend using menthol in a healing balm because it is a mild skin irritant. Likewise olive oil is high in Oleic acid which while moisturizing, can trigger acne in sensitive individuals. In a world full of amazing natural ingredients why settle for 'good enough' we strive for best.

The line can be found online, and can be shipped Nationally in both the U.S. and Canada

Can Pure Maple Syrup Help Reduce Chronic Inflammation?

First-ever Global Symposium Convenes to Review Latest Science on Natural Sweetener

LONGUEUIL, QC, April 3, 2017 /CNW Telbec/ - The first-ever global symposium solely dedicated to sharing the latest scientific discoveries on the potential health benefits of 100% pure maple products from Canada took place on April 2 in San Francisco at the 253rd annual meeting of the American Chemical Society (ACS), the largest scientific society in the world. At the symposium entitled, "Chemistry and Biological Effects of Maple Food Products," scientists from around the world shared the results of their research that expands the science of maple's potential impact on several areas affected by chronic inflammation. These include metabolic syndrome, brain health and liver disease, as well as maple's emerging link to a healthy gut microbiome.

The global symposium was organized by Dr. Navindra Seeram, who currently serves as chairman of the Division of Agricultural and Food Chemistry of the American Chemical Society, and has extensive experience examining the impact of phytonutrients in foods such as berries and pomegranates. In collaboration with the Federation of Quebec Maple Syrup Producers, Dr. Seeram has been studying the unique properties of maple in his laboratory at the University of Rhode Island since 2009. The results of his research stimulated the interest of the global scientific community, which has uncovered additional health benefits of pure maple products.

A new University of Rhode Island study highlighted at the symposium revealed the presence of inulin, a type of carbohydrate recently discovered for the first time in maple syrup. Inulin is a complex carbohydrate (natural dietary fiber) that acts as a prebiotic and works to encourage the growth of "good" or beneficial bacteria in the gut. Inulin joins the other beneficial polyphenols, vitamins and minerals already identified in pure maple syrup. This latest discovery could allow maple to be classified as a functional food.

In addition, a new study conducted on animals and also revealed at the symposium, focused on the beneficial effect of a symbiotic (prebiotic and probiotic) maple sap drink in recovering gut flora balance, which may have been lost for several reasons, including treatment with antibiotics.

"A healthy gut, with a balance of beneficial bacteria, helps to stimulate and support a healthy immune system. A healthy immune system, then, can help protect the body against chronic inflammation," said Dr. Seeram. "Chronic inflammation has shown a potential link to brain conditions such as Alzheimer's disease. As such, this research provides additional information linking pure maple syrup, a unique natural sweetener, to brain health. However, additional animal studies, along with eventual human studies, would be required to confirm these initial findings."

This year, two newly discovered additional compounds with antioxidant properties and potential health benefits have been identified in the lignan's family, bringing the total count of known phytonutrients in maple products to 65. This may help support discoveries made over the past few years on the inherent properties of maple syrup from Canada that comes directly from the sap of the maple tree, making it an all-natural product with unique health benefits. Discovered in 2011, a unique, polyphenolic molecule in maple syrup, Quebecol¹, and one of its analogues (isoquebecol, recently synthesized), have demonstrated that it significantly decreases the production of inflammation mediators.

"The 7,500 Quebec-based maple producers are committed to pursue the funding of new research to help further identify the positive health impacts of pure maple," said Serge Beaulieu, President of the Federation of Quebec Maple Syrup Producers. "This is why we have chosen to work with Dr. Seeram along with other researchers. Dr. Seeram's tremendous experience studying the impact of phytonutrients in plants and fruits has propelled maple research since he began studying the natural sweetener in 2009. There is still much to discover about maple's health benefits and the scientific community has only begun to uncover the tip of the iceberg. We will continue to allocate resources to research on maple products to discover its impacts on the human body."

Inflammation is a normal part of a healthy immune response and is a biological process that helps heal injury and fight infection. When inflammation becomes uncontrolled or chronic, it plays a role in exacerbating a variety of health-related issues. There are several ways to help prevent and combat chronic inflammation. A diet rich in foods that contain polyphenols, such as green tea, red wine, fruits and vegetables – and potentially pure maple syrup from Canada – may be beneficial for supporting a healthy immune system.

The Federation of Quebec Maple Syrup Producers does not promote an increase of sugar consumption. When choosing a sweetener for moderate use, it appears that 100% pure maple syrup from Canada has more healthful compounds compared to some other sources of sugar.

About the Federation of Quebec Maple Syrup Producers and Maple Products from Quebec

The Federation of Quebec Maple Syrup Producers (FPAQ) was founded in 1966. Its mission is to defend and promote the economic, social and moral interests of some 7,500 Quebec maple businesses, as well as to develop initiatives that collectively market the products that flow from Quebec's 44 million taps. The quality work of these maple producers has made Quebec the source, on average, of 72 percent of the world's maple syrup production and 90 percent of Canada's maple syrup output. Together, Ontario, New Brunswick and Nova Scotia contribute the other 10 percent of Canadian production.

FPAQ proudly promotes the reference brand Maple Products from Quebec in addition to coordinating the international promotion and value creation of Canadian maple products on behalf of Canada's maple industry. In this capacity, the FPAQ leads and directs the research efforts of the Réseau international d'innovation des produits d'érable du Canada.

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¹ Li, L., Seeram, N.P. Quebecol, a novel phenolic compound isolated from Canadian maple syrup. Journal of Functional Foods 2011, 3, 125-128.

SOURCE Federation of Quebec Maple Syrup Producers

2017 Canadian Green Car Award Finalists Announced

Overall winner to be revealed April 7^th at the Green Living show

TORONTO, Ont. — In what is likely the tightest competitions in its five-hear history, expert judges have selected six vehicles as finalists for the 2017 Canadian Green Car Award.

The overall winner will be revealed Friday, April 7^th, at the Green Living Show, in the Metro Toronto Convention Centre.

The finalists were selected after extensive testing and assessment by the judges, all leading Canadian automotive journalists, who picked the top entries in six technology and style categories.*

The finalists are:

The Canadian Green Car Award recognizes vehicles that offer impressive “green” attributes combined with strong mass-market appeal, based on the understanding that any product can have a significant environmental impact only if it sells in large numbers.

To achieve this result, the assessments combined “objective” criteria, such as fuel economy, emissions and price, with the judges’ evaluations of performance, driving experience, value, features and “green” qualities.

“The task for the Canadian Green Car Award judges gets more challenging as automakers continue to raise the bar in technology, fuel economy and quality,” says Laurie Simmonds, President and CEO of Green Living Enterprises, which operates the annual Green Living Show. “The six finalists are all outstanding ‘green’ vehicles, and the judges once again have their work cut out for them in making the ultimate choice.”

The competition began with the Award Steering Committee selecting three nominees in each of the six categories, based on meeting essential “green” criteria related to technology type and fuel economy. The judges then evaluated the nominees, including test drives, data from manufacturers and their own experience. Those scores produced the six category winners announced today.

“This year our judging panel was struck by how mainstream green cars have become,” notes Eric Novak, Co-creator of the Canadian Green Car Award. “The six finalists have demonstrated that by owning a vehicle with minimal environmental impact, one doesn’t need to feel they are making sacrifices in other areas.  Seeing green cars as normal instead of alternative is critical to achieve wide-spread acceptance among car buyers and our finalists this year go a long way towards proving that.”

This open process, in which eligibility doesn’t depend on whether a manufacturer is willing to pay a substantial entry fee, is in line with other global green car awards and makes the program a very meaningful gauge for consumers.

The overall 2017 Canadian Green Car Award winner will be revealed at 11:30 a.m., Friday, April 7, at the Green Living Show in the Metro Toronto Convention Centre, North Building.  Andrew Horsman, Executive Director of Ontario Tire Stewardship, will present the trophy. In addition to declaring the winner, Mr. Horsman will announce an exciting environmental achievement in tire recycling.

All six finalist vehicles will be on display throughout the three-day Show, last year attended by more than 35,000 visitors.

*Basic criteria for each category:

• Zero-emission: Battery electric, fuel cell or other zero-emission technology.
• Plug-in hybrid: Hybrid electric vehicle that uses rechargeable batteries, or another energy storage device, that can be recharged by plugging it in to an external source of electric power.
• Conventional hybrid-electric: Must have combined fuel economy of 6.0 litres per 100 kilometres or lower, according to the five-cycle Natural Resources Canada Fuel Consumption Rating or, if that is not yet available, the equivalent U.S. EPA rating.
• Gasoline or diesel internal combustion: Must have combined fuel economy of 7.0 litres per 100 kilometres or lower.
• Efficient Three-Row: A passenger vehicle of any propulsion technology with at least three forward-facing rows of seating, accommodating at least six occupants. If powered by gasoline or diesel internal combustion, or a conventional hybrid, it must have a combined fuel economy of 10.0 litres per 100 kilometres or lower.
• Fun car: Any passenger vehicle of any propulsion technology that accelerates from zero to 100 kilometres per hour in 7.5 seconds or faster. If powered by gasoline or diesel internal combustion, or a conventional hybrid, it must have a combined fuel economy of 8.1 litres per 100 kilometres or lower.

For more details on the 2017 Canadian Green Car Award, including the list of all vehicle nominees and the judges who assessed them, visit www.canadiangreencaraward.ca.

The Green Living Show takes place April 7^th to 9^th at the Metro Toronto Convention Centre. For more information on living a healthier more sustainable lifestyle, please visit greenlivingshow.ca. Join the conversation on Facebook, follow the Green Living Show on Twitter and Instagram @GreenLivingPage.

About Green Living Enterprises 

Green Living Enterprises is Canada’s leading cause-marketing agency focused on social and environmental program development. Our team is led by award-winning industry experts in the fields of brand and program development; custom content; advertising, marketing and communications; and event management. Green Living Enterprises also includes Greenlivingonline.com and The Green Living Show, Canada’s largest consumer show, dedicated to simple solutions for leading a healthy and sustainable lifestyle.

About the Green Living Show

The Green Living Show is Canada’s largest consumer show dedicated to simple solutions for leading a healthy and sustainable lifestyle. This three-day event offers inspiration for all ages and features influential speakers; innovative products; eco home and garden design; local and organic food and wine tastings; health, wellness and yoga pavilions; eco fashion and green beauty makeovers; electric car test drives; nature exhibits and fun activities for the entire family.

Getting Outside is Good for You: Five Benefits

Spring is here and families will spend more time outside dining, playing, relaxing, and gardening as the weather improves. And while they may enjoy being outside, they may not know that getting outside is also good for their health. The Outdoor Power Equipment Institute (OPEI) outlines five health benefits of getting outside:

Reason #1: Your lawn can make you happier! Our stress levels fall within minutes of seeing green spaces. Knowing and experiencing nature makes us generally happier, healthier people.

Reason #2: Getting dirty is good for you! Mycobacterium vaccae in soil mirrors the effect on neurons that Prozac provides. Give your kids a pair of gardening gloves and have them work with you in your green spaces for a hefty dose of Vitamin N(ature) and G(reen). People who spend time gardening and have direct contact with soil feel more relaxed and happier.

Reason #3: Exposure to natural settings may be widely effective in reducing attention deficit/hyperactivity disorder (ADHD) symptoms in children. Children gain attention and working memory benefits when they are exposed to greenery.

Reason #4:  Living landscapes help people and pets be healthier. Playing outdoors increases fitness levels and builds healthy, active bodies. Research also shows that children reap numerous health, social and personal benefits from spending time outside playing.

Reason #5:  Your lawn produces lots of oxygen and cleans the air too. Fifty square feet of grass generates enough oxygen each day for a family of four, and reduces the “code red” effect since grass removes pollutants from the air we breathe.

“Our living landscapes not only provide beauty, but are a stress-reliever, a recreational space, a wildlife habitat, and an outdoor living area,” said Kris Kiser, president and CEO, OPEI. “Studies show that our green spaces contribute to our health, happiness and intellect.”

Our outdoor living spaces offer great health benefits to us. Trees, shrubs, grass and flowering plants are integral to human health. They provide a place for children and pets to play and directly contribute to our mental and physical well-being.

For more information please visit www.livinglandscapesmatter.com.

GeneNews Launches Blood-Based, Biomarker Test for Breast Cancer Risk Assessment

Women with Elevated Risk Scores are Encouraged to Move to Further Screening with 3D Tomography, Screening Breast Ultrasound and/or MRI

TORONTO, March 29, 2017 /CNW/ - GeneNews Limited (TSX:GEN) ("GeneNews" or the "Company") announced today the launch of BreastSentry™, a new risk stratification test for breast cancer, via its Virginia-based clinical reference lab, Innovative Diagnostics Laboratory ("IDL"). BreastSentry incorporates a blood-based biomarker test with a sophisticated algorithm to determine a woman's five-year and lifetime risk for developing breast cancer.

BreastSentry measures the fasting plasma levels of two biomarkers in the blood, proneurotensin ("pro-NT") and proenkephalin ("pro-ENK"), which are highly predictive of a woman's risk for developing breast cancer. Various longitudinal clinical studies have shown that elevated levels of pro-NT and decreased levels of pro-ENK are strong, independent risk factors for the development of breast cancer.^1-17 In addition, BreastSentry measures seven key risk factors, based on the Gail Model, for developing breast cancer to provide an additional level of personal data into the risk stratification algorithm to create an enriched, personalized score. The Gail Model is a statistical breast cancer risk assessment algorithm designed by scientists at the U.S. National Cancer Institute and the National Surgical Adjuvant Breast and Bowel Project to estimate a woman's risk of developing invasive breast cancer.

BreastSentry is intended for use in average risk women who have no family history of breast cancer. However, it is especially suited for the approximate 50% of women who have dense breasts and, therefore, require further risk stratification where mammography leaves off. Elevated risk scores can help physicians determine if further screening with 3D Tomography, Screening Breast Ultrasound and/or MRI are necessary. Women with elevated risk scores are also encouraged to adopt lifestyle changes in diet and exercise to reduce risk moving forward.

"We are excited to make this test available to women throughout the U.S. who are concerned with their risk for developing breast cancer, especially those 50% of U.S. women with dense breast tissue, who cannot rely on mammography alone to determine if they currently have the disease," said James Howard-Tripp, Chairman and CEO of GeneNews.

Approximately two-thirds of pre-menopausal and one-quarter of post-menopausal women have dense breast tissue, which makes it challenging to detect breast cancer by mammography alone.⁶ High breast density, as seen on a mammogram, is linked to an increased risk of breast cancer. Women with heterogeneously (40%) and extremely dense breast (10%) tissue are four-to-five times more likely to develop breast cancer than women with low breast density.^18,19

The American Cancer Society suggests women with dense breasts talk to their health care providers about whether they should consider adding MRI and/or Ultrasound to their annual mammography screening.²⁰  To help physicians determine what comes next following either an elevated or normal BreastSentry test score, GeneNews and IDL have also developed a BreastSentry Patient Advocacy Protocol.

"This is a significant breakthrough for women with dense breasts," commented Dr. Belinda Barclay-White, founder and medical director of Arizona Breastnet, a full service diagnostic breast center. "Any additional information that can be added to a patient profile to determine ongoing risk for developing breast cancer is very much needed to help physicians, radiologists and patients determine what the next course of action should be."

About GeneNews

GeneNews is committed to becoming a leader in advanced diagnostics and personalized medicine, serving as a strong commercialization outlet for early detection of cancer and other chronic diseases. Our mission is to identify, assess and make commercially available a comprehensive menu of diagnostics that provide physicians and patients with personalized clinical intelligence and actionable information to improve health out-comes through the early diagnosis of disease.  Our Richmond, Virginia-based Innovative Diagnostic Laboratory clinical reference lab specializes in traditional and advanced clinical evidence-based blood testing that helps find, understand, and address cancer risk in patient populations. Currently, IDL offers risk assessment blood tests for four major cancer types - colon, lung, prostate and breast. GeneNews' common shares trade on the Toronto Stock Exchange under the symbol 'GEN'. More information on GeneNews can be found at www.GeneNews.com.

Forward-Looking Statements

This press release contains forward-looking statements identified by words such as "expects", "will" and similar expressions, which reflect the Company's current expectations regarding future events. The forward-looking statements involve risks and uncertainties that could cause the Company's actual events to differ materially from those projected herein. Investors should consult the Company's ongoing quarterly filings and annual reports for additional information on risks and uncertainties relating to these forward-looking statements. The reader is cautioned not to rely on these forward-looking statements. The Company disclaims any obligation to update these forward-looking statements, except as required by law.

References

^{1.        Melander O. et al., Plasma Proneurotensin and Incidence of Diabetes, Cardiovascular Disease, Breast Cancer, and Mortality, JAMA (Journal of the American Medical Association). October 10, 2012, Issue 308, 14, P. 1469-75.
2.        Melander O, et al., Validation of plasma proneurotensin as a novel biomarker for the prediction of incident breast cancer, Cancer Epidemiol Biomarkers Prev. August, 2014; 238 : P. 1672-6.
3.        Ernst, A, et al., Proneurotensin 1-117, a stable neurotensin precursor fragment identified in human circulation. Peptides. July, 2006, Issue 27, 7, P. 1787-93.
4.        Dupouy S, et al., The Neurotensin Receptor-1 Pathway Contributes to Human Ductal Breast Cancer Progression. PLoS ONE. 2009;41: e4223
5.        Souazé F, et al., Expression of Neurotensin and NT1 Receptor in Human Breast Cancer: A Potential Role in Tumor Progression. Cancer Res. June 15, 2006;6612: 6243-9.
6.        Carraway, R. et al., Involvement of neurotensin in cancer growth: Evidence, mechanisms and development of diagnostic tools. Peptides. October, 2006;2710: 2445-60.
7.        Devader, C. et al, The Anti-Apoptotic Role of Neurotensin. Cells. March, 2013; 21:
8.        Go, V. et al, Role of nutrients in the gastrointestinal release of immunoreactive neurotensin, Peptides. 1981;2 Suppl 2: 267-9.
9.        Dupouy S, et al, The potential use of the neurotensin high affinity receptor 1 as a biomarker for cancer progression and as a component of personalized medicine in selective cancers. Biochimie. 2011 Sep;939:1369-78. doi: 10.1016/j.biochi.2011.04.024. Epub 2011 May 17.
10.     Somai S. et al, Neurotensin counteracts apoptosis in breast cancer cells, Biochemical and Biophysical Research Communications, Volume 295, Issue 2, 12 July 2002, Pages 482â€"488
11.     Melander, O, et al, Plasma Pro-Enkephalin, a stable peptide of the precursor to the endogenous opioid Enkephalin, predicts breast cancer risk, Oncol Res Treat 2014;37(suppl 1): 4
12.     Melander, O. Plasma Pro-Enkephalin adds value to Proneurotensin for the risk prediction of incident breast cancer. Oncol Res Treat 2014;37(suppl 1): 6
13.     Ernst A, Proenkephalin A 119-159, a stable proenkephalin A precursor fragment identified in human circulation.Peptides. July, 2006;27: 1835-40.
14.     Faith, R. et al, Inhibition of Pulmonary Metastases and Enhancement of Natural Killer Cell Activity by Methionine-Enkephalin, Brain Behav Immun. June, 1988;2: 114-22.
15.     Schäfer, M. et al, Opioid therapy and tumor progression. Advances in Palliative Medicine 2009, 8, 53–56
16.     Mernenko OA, et al, Met-enkephalin induces cytolytic processes of apoptotic type in K562 human erythroid leukemia cells. FEBS Lett. April 1, 1996;3833: 230-2.
17.     Maneckjee R, et al, Opioids induce while nicotine suppresses apoptosis in human lung cancer cells Cell Growth Differ. October, 1994;510: 1033-40.
18.     Boyd NF, Guo H, Martin LJ, et al. Mammographic density and the risk and detection of breast cancer. N Engl J Med. 3563:227-36, 2007.
19.     Tamimi RM, Byrne C, Colditz GA, Hankinson SE. Endogenous hormone levels, mammographic density, and subsequent risk of breast cancer in postmenopausal women. J Natl Cancer Inst. 9915:1178-87, 2007.
20.     Saslow D, Boetes C, Burke W, et al. for the American Cancer Society Breast Cancer Advisory Group. American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. CA Cancer J Clin. 572:75-89, 2007.}

SOURCE GeneNews Limited

Women's College Hospital brings accessible BRCA genetic testing to Canadians

Women's College Hospital research study, The Screen Project, provides access to affordable population-based genetic testing

TORONTO, March 28, 2017 /CNW/ - Approximately one in 200 Canadians have a BRCA1 or BRCA2 mutation which puts women at a higher lifetime risk of developing breast and ovarian cancer, while male mutation carriers are at an increased risk of developing prostate and other cancers. Currently, genetic testing for these gene mutations is only offered to, and covered for, people who meet eligibility criteria based on several factors like a strong family history of cancer. Researchers in the Familial Breast Cancer Research Unit at Women's College Hospital (WCH) will lead a population-based study called The Screen Project that will offer genetic testing for BRCA1 and BRCA2 gene mutations to Canadians at a cost of $165 USD. U.S.-based Veritas Genetics, the global leader in genetic sequencing and interpretation, will be performing the BRCA genetic testing. The study hopes to determine the feasibility of guided direct-to-consumer population-based genetic testing for BRCA1 and BRCA2 gene mutations and also to estimate the number of cancers that would be prevented through such a program.

Hereditary mutations in the BRCA1 or BRCA2 gene are responsible for five to 10 per cent of breast cancers and 10 to 15 per cent of ovarian cancers. Although knowledge about hereditary cancers has improved, referral rates for genetic testing remain low among primary care physicians. A recent study found that only 23 per cent of eligible ovarian cancer patients were referred for genetic assessment. Research on the underutilization of genetics in clinical care shows that the majority of BRCA mutation-carriers in the population will go undetected.

"The technology for identifying BRCA1 and BRCA2 mutation-carriers has improved dramatically since their discovery in the mid 1990s. However, we have not yet achieved our potential in preventing breast and ovarian cancers among women using genetic testing," says Dr. Steven Narod, co-principal investigator and the director of the Familial Breast Cancer Research Unit at WCH. "Population-based genetic testing is a new approach for widespread testing in Canada that we hope will change that paradigm."

Narod is a co-discoverer of BRCA1 and BRCA2 genes and the recipient of the 2016 Basser Global Prize for his work on breast and ovarian cancer genetics.

"The Screen Project aims to address the health gaps in eligibility criteria that currently exist by offering this genetic test to any interested Canadian at a more accessible price," says Dr. Mohammad Akbari, co-principal investigator and director of the Research Molecular Genetics Laboratory at WCH. He led the international team discovered RECQL as the latest breast cancer susceptibility gene in 2015.

Individuals who are interested in BRCA genetic testing can participate in the study by registering online at www.thescreenproject.ca. On the registration site, patients will have access to an informational video and educational materials to learn more about hereditary cancer and genetic testing. Once participants have provided the necessary information and consent, they will be directed to Veritas' website to submit payment and have a saliva collection kit shipped to their home. Those who are unable to afford the cost of the test will be eligible for financial assistance. Saliva samples will then be tested at Veritas' laboratory and the results will be reported to the patient within two to four weeks. Individuals who test positive for the BRCA mutation will be contacted by the Familial Breast Cancer Research Unit at WCH, while those who receive a negative or inconclusive result will receive a report from Veritas Genetics.

"The current barriers to accessing genetic testing in the healthcare system can prevent or delay people from obtaining knowledge that can significantly reduce their cancer risk," says Nicole Gojska, genetic counsellor at Women's College Hospital. "Several options are available to detect cancers early or reduce the risk of cancer from happening. For example, for women, these options can include intensified screening, taking medications to reduce cancer risks or preventative surgery. As genetic testing for cancer predisposition is becoming increasingly more common in clinical practice, men and women with BRCA mutations may also benefit from tailored cancer treatments."

Direct-to-consumer genetic testing needs to be guided by a medical professional with long-term follow-up and management. All participants who are identified as BRCA mutation-carriers through this study will be offered a follow-up consultation with a WCH genetic counsellor to review their test and discuss the implications of their diagnosis. By providing genetic testing that is equitable and accessible to all Canadians, WCH hopes to demonstrate a new model of care for breast, ovarian and prostate cancer prevention that will close the gaps that exist within the healthcare system.

About Women's College Hospital For more than 100 years Women's College Hospital (WCH) has been developing revolutionary advances in healthcare. Today, WCH is a world leader in the health of women and Canada's leading, academic ambulatory hospital. A champion of equitable access, WCH advocates for the health of all women from diverse cultures and backgrounds and ensures their needs are reflected in the care they receive. It focuses on delivering innovative solutions that address Canada's most pressing issues related to population health, patient experience and system costs. The WCH Institute for Health System Solutions and Virtual Care (WIHV) is developing new, scalable models of care that deliver improved outcomes for patients and sustainable solutions for the health system as a whole.

Women's College Research Institute (WCRI) is tackling some of the greatest health challenges of our time. Its scientists are conducting global research that advances the health of women and improves healthcare options for all, and are then translating those discoveries to provide much-needed improvements in healthcare worldwide.

For more information about how WCH and WCRI are transforming patient care, visit www.womenscollegehospital.ca and www.womensresearch.ca

About Veritas Genetics Veritas Genetics is a global leader in providing in genetic testing, interpretation, and storage services to individuals, physicians, and medical researchers. By removing barriers to genetic screening and whole genome sequencing, Veritas Genetics empowers individuals and doctors to make informed lifestyle decisions that help people live longer, healthier lives. The company was recognized by MIT Technology Review as one of the top "50 Smartest Companies" in 2016. Veritas was founded by leaders in genomics from Harvard Medical School and operates globally from its offices in the U.S., Europe and China. Learn more at www.veritasgenetics.com.

SOURCE Women's College Hospital

Patient advocacy experts gather to start a conversation on cancer immunotherapy in Canada

Inaugural patient summit brings together experts across oncology to collaborate on patient access to innovative cancer treatments and foster collaboration amongst patient groups and the medical community to improve patient outcomes

TORONTO, March 27, 2017 /CNW/ - The Immuno-Oncology Network for Patient Organizations today announced its inaugural Patient Leader Education Summit, scheduled for Friday, March 31 to Saturday, April 1, 2017 at the St. James Cathedral Centre in Toronto. The Summit will bring together some of Canada's leading patient advocates in oncology for a two-day meeting intended to educate and identify solutions to expand access to cancer immunotherapy treatments.

"Cancer immunotherapy medicines have been one of the greatest advancements in cancer treatment, allowing patients with metastatic and advanced disease a real chance of survival, and I am living proof of this reality," says Kathy Barnard, Founder and President at the Save Your Skin Foundation. "Now, we must unify the patient voice and empower patient advocates and patients to be fully engaged in healthcare decision-making, to work together with all the stakeholders involved towards solutions for a sustainable system, and to ensure that cancer patients have access to innovative cancer therapies."

A highlight of the event will be a discussion about the landscape of cancer therapy today and a look at the future of cancer therapy led by world-leading cancer immunotherapy researcher Dr. John Bell from the Ottawa Hospital. Dr. Bell will be joined by renowned medical oncologist Dr. Marcus Butler from the Princess Margaret Cancer Centre, University Health Network, where he is also the director of the immune monitoring laboratory.

"Cancer immunotherapy is a class of treatments which stimulate a person's own immune system to target and attack cancer cells," says Dr. John Bell. "Right now, immunotherapy treatments have been used in patients with melanoma, lung and kidney cancers, and research continues to extend their use to include different types of cancer. The possibility for immunotherapy has yet to be realized. We also continue to evolve our research in other areas of care, as we know immunotherapy won't work for everyone. Having a wide range of options for patients continues to be important."

"As the landscape in cancer treatment evolves to include cancer immunotherapy and other innovative treatment options, medical professionals have a responsibility to collaborate with patients and patient advocates to meet the current and future needs of patients," says Dr. Marcus Butler. "If we work together, we have the potential to improve access to treatments, companion diagnostics, and supportive care and, most importantly, ensure the highest safety and effectiveness of care for everyone."

Summit topics will include the importance of taking a patient-focused approach to care, a panel discussion about the role for patient advocates in the regulatory process, and issues of access to cancer immunotherapy and innovative treatments. The group will develop an action plan that will identify tangible areas of improvement in cancer care delivery.

The event will feature speakers offering diverse perspectives and opinions based on their experience, including:

• Dr. Marcus Butler, Medical Oncologist, Princess Margaret Cancer Centre, University Health Network
• Dr. John Bell, Researcher, The Ottawa Hospital
• Monette Greenway, Principal & Co-Founder, Precision Rx-Dx
• Imran Ali, Senior Manager, pan-Canadian Pharmaceutical Alliance (pCPA)
• Scott Gavura, Director, Provincial Drug Reimbursement Cancer Care Ontario (CCO)
• Alexandra Chambers, Director, pan-Canadian Oncology Drug Review (pCODR)
• Marie Hotte, Scientific Coordinator, Institut national d'excellence en santé et en services sociaux (INESSS) via video
• Heather Logan, Executive Director, Canadian Association of Provincial Cancer Agencies (CAPCA)
• Dr. Reiner Banken, Senior Fellow, Institute for Clinical and Economic Review (ICER)
• Joanne Castonguay, Research Director, Institute for Research on Public Policy (IRPP)
• Dr. Femida Gwadry-Sridhar, Founder & CEO, Pulse Infoframe
• Ryan Peck, Executive Director of the HIV & AIDS Legal Clinic Ontario (HALCO)
• Martine Elias, Director Access, Advocacy & Community Relations, Myeloma Canada

About the Immuno-Oncology Network for Patient Organizations
The Immuno-Oncology Network for Patient Organizations emerged when several patient organization leaders from across Canada began to discuss the needs for a collaborative strategy focused on access to cancer immunotherapy treatments for patients in Canada. The Immuno-Oncology Network for Patient Organizations is dedicated to raising awareness of the needs of cancer patients and their families. Our goal is to work together to promote greater education and understanding of therapies to ensure that Canadians have equal, timely access to these therapies, companion diagnostics, and supportive care.

Steering Committee members of the Immuno-Oncology Network for Patient Organizations include the following:

• Kathy Barnard, Save Your Skin Foundation
• Canadian Cancer Survivor Network
• Heather Chappell, Kidney Cancer Canada
• Annette Cyr, Melanoma Network of Canada
• Martine Elias, Myeloma Canada
• Elizabeth Lye, Lymphoma Canada
• Christina Sit, Lung Cancer Canada
• Barry Stein, Colorectal Cancer Association of Canada

SOURCE The Immuno-Oncology Network for Patient Organizations

From Elizabeth DeRosa of Finding The Way Integrative Nutrition Health Coach & Author 

http://findingtheway.net

The Gifts I Received from Having a Benign Brain Tumor

“I am sorry to tell you this Elizabeth but, you have a large acoustic neuroma”. Those were the unexpected and terrifying words that came out of my doctor’s mouth when I went to see him after having an MRI to determine the cause of my symptoms. As you can imagine, my world stopped and I immediately thought I was going to die.  What is a person to do after receiving news like this?

This journey has had many challenges and moments of uncertainty, but it has also taught and continues to teach me many important and valuable lessons that I have incorporated into my daily life and self-care practice. I believe some of these gifts or lessons can be applied to anyone’s life regardless of their health or medical issues.

The lessons I have learned include not only the reality of physical strengths and challenges but more importantly, it is teaching me the genuine and heartfelt importance of emotional wellness.

I share with you now some of the actions, tips, and ideas that I was gifted with during this time to help me overcome my diagnosis and surgery side effects. I do that to bring awareness to the idea that healing is a journey of the body, mind, and spirit. Healing is a process that requires your attention and commitment.

Gifts

• Life is a beautiful and mysterious gift. Being diagnosed with a medical condition is not a punishment (regardless of outcome) and there can be gifts that you find along the way if you are willing to open your eyes.

• Somehow during this difficult time in my life, I was surprised and blessed to feel the Grace of God in ways that I had never experienced before on a conscious level.  I was a witness to Grace and it’s many forms including humility, love, patience, faith, vulnerability, forgiveness, struggle, patience, empathy, freedom, laughter, gratitude, and hope.

• I have learned to begin to understand my body in a different way moving forward. I listen more closely to the messages it is sending me.
• Receiving. Moms typically give of themselves first before they ever think about their own needs. To be the person who needed help and allowing others to give to me was one of the most valuable lessons.
• Advocacy. I identified what I wanted in regard to outside support and began putting that in place to help with pre-surgery concerns and post-surgery side effects. I researched my type of brain tumor, doctors and hospitals, procedures, insurance coverage, post-surgery specialists, and so on to help me make the best decision regarding these important issues. I was an active participant in my treatment plan. Ask questions and get second and third opinions, if necessary.
• Use an integrative approach to health. I utilized alternative modalities including acupuncture, holistic therapy, cranial sacral massage, castor oil packs and homeopathic remedies, holistic nutrition, reiki, and aromatherapy. I also worked with neurosurgeon, ENT, occupational and physical therapist, audiologist, and neuro-opthamologist.  I worked with incredible people and healers to assist in my recovery.
• Communication. I learned the importance of effectively communicating with others. I gained an ability to express myself in a way that allows for more personal freedom in deciding what is right for me.
• Boundaries. I learned the importance of setting appropriate boundaries with people and myself. Being able to set boundaries allows me the freedom to live from an authentic place of being.
• Healthy eating has provided me with proper nutritional balance and has lowered inflammation in my body.
• Life is not so serious and there is room for laughter and to view the world through the eyes of a child.
• Simplicity - We have overcomplicated most aspect of our lives. We can reduce stress and the “busyness” to create more harmony in our lives or we can learn to live in harmony with ourselves despite the stress and chaos.
• Perfection - I have learned that there is no need to try and be perfect. It takes so much our daily energy to strive for others to see us as “having it all together”. I embrace the thought that I am not the perfect mother, wife, neighbor, or person. I do my best but also know that I do not have to waste my time and energy trying to create that image for myself. Letting go of this thought has created independence in my life. I believe it has also allowed others around me to be who they are without the pressure of being “perfect”.
• We are all in this together!
• A diagnosis or medical issue does not define who you are as a human being. It is part of your life’s journey, but we don’t need to limit our beliefs about ourselves. We are so much more than our physical limitations.
• Our bodies are bio-computers with the ability for self-healing. We can learn how to activate those healing powers within to bring well-being to many areas of our lives.

This has been a long and challenging road as I learn to navigate my world differently with physical challenges, but, changing my thoughts, being an advocate on my behalf, communicating more effectively, and accepting where I am today has given my life a new purpose and allowed me to humbly see the beauty and mystery of life.

From Elizabeth DeRosa of Finding The Way Integrative Nutrition Health Coach & Author 

http://findingtheway.net

Patient to Advocate Lessons

Today most Americans rely on healthcare professionals to “manage” their health and well-being. We listen to the experts about our physical concerns and follow the treatment plan laid out to us with strict guidance. We do it without asking many questions or getting a second opinion. Most of us follow the medical advice in an attempt to eliminate symptoms or disease, to feel better, and so that we can get back to our daily lives quickly.

While it is necessary to follow the protocol advised by your doctor, it is also important to become your own advocate in terms of your health. Our healthcare system now employs patient advocates as part of a multi-disciplinary team that specialize in supporting patients with issues ranging from consent, privacy and confidentiality, and patient rights.

But, did you know that you can be your own advocate? Not many people understand that you can become your own advocate and contribute to your own healthcare decisions that make you an active member of any medical team working on your behalf. You can do this whether you are visiting the doctor for a well check-up, sick visit, surgical procedure, post-operative care, or being followed for a chronic disease.

Tips to Become Your Own Self-Advocate

• We are all uniquely different and a treatment plan that works for one person may not work for another. This does not mean you or your doctor have failed, it means that another approach must be taken to activate your body’s own ability to heal itself. The doctor is the medical expert but you are an expert on you and your body.
• Become an active and engaged participant in your treatment plan. Do not be a passive by-stander. This is your life! You are paying the doctor to work for you. If it doesn’t feel right, seek out a different doctor or get a second opinion.
• Get a copy of your medical and/or prescription issue. Review your history! Keep a medical journal if desired.
• Communication is crucial. Ask questions and don’t be afraid to ask for clarification or to tell your doctor, “I don’t understand”. Your doctor must take the time to answer any and all question that you have regarding your concerns.
• Be prepared and come to your appointment with a list of questions. It is easy to forgot them during the appointment.
• Understand how your insurance plan works. The insurance industry is a complex system within the medical umbrella that can leave patients frustrated and exhausted. Know what services are covered and plan accordingly with you doctor.
• Know your doctor’s medical background. Where and what did they study? Observe their manners and behaviors. Do they listen to your concerns, show respect for this partnership, communicate effectively, and have a commitment to your well-being?

The doctor-patient relationship is changing today. This relationship is essential and must be utilized effectively for delivering high-quality healthcare to you. It is important to forge an improved dialogue, become an active participant, and ask questions so that you can become knowledgeable and empowered in regard to your health and wellness.

New Documentary ‘What the Health,’ the health film that health organizations don’t want you to see, hits top spot on Vimeo

SAN FRANCISCO, Calif., – “What the Health,” a new feature-length documentary, captured Vimeo On Demand’s number one trending spot, and racked up more than 6.5 million social media shares, following its release Thursday. “What the Health” exposes the collusion and corruption in government, big business, and the nation’s leading health organizations. With heart disease and cancer the leading causes of death in America, diabetes at an all-time high, costs and healthcare costs in the trillions, “What the Health” reveals possibly the largest health cover-up of our time.

Proceeds from online views raised more than $45,000 for hunger relief organization Food Not Bombs.

Intrepid filmmaker Kip Andersen tracks down the leading and most trusted American health nonprofits to find out why these groups are staying silent, despite a growing body of evidence. Audiences will be shocked to learn the insidious roles played by pharmaceutical companies, agribusiness, and processed animal food companies in the nation’s health, especially in the most vulnerable communities, and will cheer at the transformation and recovery of those who took their lives into their own hands.

“Like a lot of Americans, I have a family history of diabetes, heart disease, and cancer, so it was important to me to learn more,” said Andersen, who co-directed the film with Keegan Kuhn. “We are astonished by the support for ‘What the Health’ and hope it contributes to the national conversation about our health, and how big business influences it.”

Surprising, and at times hilarious, the documentary features the insights of urgent care physician Dr. Milton Mills; bariatric medicine specialist Dr. Garth Davis (“Big Medicine”); Dr. Neal Barnard, president of the Physicians Committee for Responsible Medicine; physician and bestselling author Dr. Michael Greger (“How Not to Die”); NYU School of Medicine professor Dr. Michelle McMacken; public health attorney Michele Simon (“Appetite for Profit: How the Food Industry Undermines Our Health and How to Fight Back”), and many more.

“We're so grateful to Kip and Keegan for making us part of this incredible film and for their generosity in supporting our efforts to share healthy vegan food with the public, many who are hungry and homeless, struggling to find nourishment in communities across North America and the globe,” said Keith McHenry, co-founder of Food Not Bombs.

For a press kit, photos, and other media resources visit https://app.box.com/s/7um6eicrfbnw6tnviblemc00b7lfjode

For the trailer visit https://vimeo.com/ondemand/whatthehealth

For more information visit http://www.whatthehealthfilm.com.

About AUM Films and Media

AUM Films and Media is a 501c3 non-profit focused on creating films and media that promote thrivability, compassion, and harmony for all life. “Cowspiracy: The Sustainability Secret,” its first production, premiered in late 2014. This documentary uncovers the most destructive industry facing the planet today – and investigates why the world's leading environmental organizations are too afraid to talk about it. For more information visit http://aumfilms.org.